Determination of the Monomer-Dimer Equilibrium of Interleukin-8 Reveals It Is a Monomer at Physiological Concentrations

Biochemistry

Volumn 33, Issue 43, 1994, Pages 12741-12745

  Burrows, Stephen D ^a,b,c,d   Doyle, Michael L ^a,b,c,d   Murphy, Kenneth P ^a,b,c   Franklin, Samuel G ^a,b,c,d   White, John R ^a,b,c,d   Brooks, Ian ^a,b,c,d   McNulty, Dean E ^a,b,c,d   Scott, Miller O ^a,b,c,d   Knutson, Jay R ^a,b,c,e   Porter, Denise ^a,b,c,e   Young, Peter R ^a,b,c,d   Hensley, Preston ^a,b,c,d  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF IOWA   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d SmithKline Beecham Pharmaceuticals   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; COMPLEMENTARY DNA; DIMER; FURA 2; INTERLEUKIN 8; INTERLEUKIN RECEPTOR; MONOMER;

ANISOTROPY; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DISSOCIATION CONSTANT; HUMAN; HUMAN CELL; MICROCALORIMETRY; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY;

CALORIMETRY; COMPARATIVE STUDY; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; HUMAN; INTERLEUKIN-8; MACROMOLECULAR SYSTEMS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; THERMODYNAMICS; ULTRACENTRIFUGATION;

EID: 0028102938     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00209a002     Document Type: Article

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