SCOPUS 정보 검색 플랫폼

Volumn 35, Issue 50, 1994, Pages 9387-9390

A facile preparation of 2- and 5-substituted 3-bromothiophenes

Author keywords

[No Author keywords available]

Indexed keywords

3 BROMOTHIOPHENE DERIVATIVE; ORGANOBROMINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0028096576 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4039(00)78549-2 Document Type: Article

Times cited : (27)

References (19)

1
- 1542523441
- John Wiley and Sons, New York
- (1992) Thiophene and its Derivatives , vol.5 , pp. 802
- Gronowitz¹

2
- 0003714767
- M. Dekker, New York
- (1986) Handbook of Conducting Polymers
- Skotheim¹

3
- 84912960082
- Synthetische Versuche mit Thiodiglykolsäureester
- (1910) Berichte der deutschen chemischen Gesellschaft , vol.43 , pp. 901
- Hinsberg¹

6
- 84945078929
- Polyacetylenverbindungen, LX. Über die Kondensation von Acetylencarbonsäureestern mit Mercaptanen
- (1964) Chemische Berichte , vol.97 , pp. 2109
- Buhlmann¹ Bresinsky²

7
- 0004205237
- Interscience Publishers, New York
- (1952) Thiophene and Its Derivatives
- Hartough¹

8
- 33845278626
- Synthesis of main group heterocycles by metallacycle transfer from zirconium
- (1988) Journal of the American Chemical Society , vol.110 , pp. 2310
- Fagan¹ Nugent²

10
- 84986405913
- Acid-Catalyzed Cyclization Reactions of Substituted Acetylenic Ketones: A new Approach for the Synthesis of 3-Halofurans, Flavones, and Styrylchromones
- (1989) Helvetica Chimica Acta , vol.72 , pp. 447
- Obrecht¹

12
- 84912958622
- As an alternative approach, we prepared in analogy to 1 (Scheme 2) tert-Butyl prop-2-ynyl sulfide 9 as a synthetic equivalent of 1, starting from 2-Methyl-2-propanthiol and propargyl bromide. 9 allowed us to synthesize the corresponding acetylenic ketones 4 and the acetylenic acetals of 6 in high yields, which smoothly cyclized to the 3-bromothiophenes 7 and 8. Due to the foul stench of 9 and its derivatives, we focussed primarily on the development of 1.

13
- 84912971537
- 2S (408.515) : C 79.38, H 4.93, S 7.85 ; found : C79.11, H 4.80, S 7.69.

16
- 0002714675
- Rapid chromatographic technique for preparative separations with moderate resolution
- (1978) The Journal of Organic Chemistry , vol.43 , pp. 2923
- Still¹ Kahn² Mitra³

17
- 84912983626
- 2Br (245.152) : C 39.20, H 2.06, S 26.16 ; found : C39.32, H 2.16, S 25.91.

18
- 84912968313
- 19SBr (275.25) : C 52.36, H 6.96, S 11.65 ; found : C 52 18, H 7.10, S 11.84.

19
- 84912992046
- The 3-bromothiophenes should be stored in the freezer and protected from light. They are best used immediately after their preparation for further transformations.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.