TNF and its receptor antibody agonist differ in mediation of cellular responses

Journal of Immunology

Volumn 153, Issue 5, 1994, Pages 2248-2257

  Totpal, Klara ^a   LaPushin, Ruth ^a   Kohno, Tadahiko ^b   Darnay, Bryant G ^a   Aggarwal, Bharat B ^a,c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; CYTOKINE RECEPTOR; RECEPTOR ANTIBODY; RECOMBINANT TUMOR NECROSIS FACTOR;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN K 562; DRUG ACTIVITY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIBODIES; CELL DIVISION; CELL LINE; CYCLOHEXIMIDE; GENE EXPRESSION; HUMANS; MOLECULAR WEIGHT; RECEPTORS, IGG; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0028094824     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Carswell, E. A., L. J. Old, R. L. Kassel, S. Green, N. Fiore, and B. Williamson. 1975. An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Nail. Acad. Sci. USA 72:3666.
2. Aggarwal, B. B., W. J. Kohr, P. E. Hass, B. Moffat, S. A. Spencer, W. J. Henzel, T. S. Bringman, G. E. Nedwin, D. V. Goeddel, and R. N. Harkins. 1985. Human tumor necrosis factor: production, purification and characterization. J. Biol. Chem, 260:2345.
3. Pennica, D., G. E. Nedwin, J. F. Hayflick, P. H. Seeburg, M. A. Palladino, W. J. Kohr, B. B. Aggarwal, and D. V. Goeddel. 1984. Human tumor necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 312:724.
4. Tracey, K. J., B. Beutler, S. F. Lowry, J. Merryweather, S. Wolpe, I. W. Milsark, R. J. Hariri, T. J. Fahey III, A. Zentella, J. D. Albert, G. T. Shines, and A. Cerami. 1986. Shock and tissue injury induced by recombinant human cachectin. Science 234:470.
5. Le, J., and J. Vilcek. 1987. TNF and IL-4 cytokines with multiple overlapping biological activities. Lab. Invest. 56:234.
6. Aiyer, R. A., and B. B. Aggarwal. 1988. Tumor necrosis factors. In CRC Handbook on Cytolytic Lymphocytes and Complement: Effectors of the Immune System. E. R. Podack, ed. CRC Press, Inc., Boca Raton, FL, p. 105.
7. Goeddel, D. V., B. B. Aggarwal, P. W. Gray, D. W. Leung, G. E. Nedwin, M. A. Palladino, J. S. Patton, D. Pennica, H. M. Shepard, B. J. Sugarman, and G. H. W. Wong. 1986. Tumor necrosis factors: gene structure and biological activities. Cold Spring Harbor Symp. Quant. Biol. L1:597.
8. Sugarman, B. J., B. B. Aggarwal, P. E. Hass, I. S. Figari, M. A. Palladino, and H. M. Shepard. 1985. Recombinant human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro. Science 230:943.
9. Vilcek, J., V. J. Palombella, D. Henriksen-DeStefano, C. Swenson, R. Feinman, M. Hirai, and M. Tsujimoto. 1986. Fibroblasts growth enhancing activity of tumor necrosis factor and ils relationship to other polypeptide growth factors. J. Exp. Med. 163:632.
10. Aggarwal, B. B., and J. Vilcek. 1992. Tumor Necrosis Factor: Structure, Function and Mechanism of Action. Marcel Dekker, New York, pp. 1-624.
11. Loetscher, H. Y., C. E. Pan, H. W. Lahm, R. Gentz, M. Brockhaus, H. Tabuchi, and W. Lesslauer. 1990. Molecular cloning and expression of the human 55-kd tumor necrosis factor receptor. Cell 61:351.
12. Schall, T. J., M. Lewis, K. J. Koller, A. Lee, G. C. Rice, G. H. Wong, T. Gatanaga, G. A. Granger, R. Lentz, H. Raab, W. J. Kohr, and D. V. Goeddel. 1990. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61:361.
13. Smith, C. A., T. Davis, D. Anderson, L. Solam, M. P. Beckmann, R. Jerzy, S. K. Dower, D. Cosman, and R. G. Goodwin. 1990. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248:1019.
14. Nophar, Y., O. Kemper, C. Brakebusch, H. Engelman, R. Zwang, D. Aderka, H. Holtman, and D. Wallach. 1990. Soluble forms of tumor necrosis factor receptors (TNF-Rs): the cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. EMBO J. 9:3269.
15. Heller, R. A., K. Song, M. A. Onasch, W. H. Fischer, D. Chang, and G. M. Ringold. 1990. Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor. Proc. Natl. Acad. Sci. USA 87:6151.
16. Kohno, T., M. T. Brewer, S. L. Baker, P. E. Schwartz, M. W. King, K. K. Hal, C. H. Squires, R. C. Thompson, and J. Vannice. 1990. A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor. Proc. Natl. Acad. Sci. USA 87:8331.
17. Himmler, A., I. Maurer-Fogy, M. Kronke, P. Scheurich, K. Pfizenmaier, M. Lantz, I. Olsson, R. Hauptmann, C. Stratowa, and G. R. Adolf. 1990. Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein. DNA Cell Biol 9:705.
18. Gray, P. W., K. Barrett, D. Chantey, M. Turner, and M. Feldmann. 1990. Cloning of human tumor necrosis factor (TNF) receptor CDNA and expression of recombinant soluble TNF-binding protein. Proc. Natl. Acad. Sci. USA 87:7380.
19. Barrett, K., D. A. Taylor-Fishwick, A. P. Cope, A. M. Kissonerghis, P. W. Gray, M. Feldmann, and B. M. J. Foxwell. 1991. Cloning, expression and cross-linking analysis of the murine p55 tumor necrosis factor receptor. Eur. J. Immunol. 21:1649.
20. Hohmann, H. P., R. Remy, M. Brockhaus, and A. P. G. M. van Loon. 1989. Two different cell types have different major receptors for human tumor necrosis factor (TNF-α). J. Biol. Chem. 264:14927.
21. Brockhaus, M., H.-j. Schoenfeld, E.-J. Schlaeger, W. Hunziker, W. Lesslauer, and H. Loetscher. 1990. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc. Natl Acad. Sci. USA 87:3127.
22. Hohmann, H.-p., R. Remy, B. Poschl, and A. P. G. M. van Loon. 1990. Tumor necrosis factors-α and -β bind to the same two types of tumor necrosis factor receptors and maximally activate the transcription factor NF-κB at low receptor occupancy and within minutes after receptor binding. J. Biol. Chem. 265:15183.
23. Erikstein, B. K., E. B. Smeland, H. K. Blomhoff, S. Funderud, K. Prydz, W. Lesslauer, and T. Espevik. 1991. Independent regulation of 55-kDA tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes. Eur. J. Immunol. 21:1033.
24. Dembic, Z., U. Loetscher, U. Gubler, Y.-C. E. Pan, H.-w. Lahm, R. Gentz, M. Brockhaus, and W. Lasslauer. 1990. Two human TNF receptors have similar extracellular, but distinct intracellular domain sequences. Cytokine 2:231.
25. Hatakeyama, M., M. Tsudo, S. Minato, T. Kono, T. Miyata, M. Miyasaka, and T. Taniguchi. 1989. Interleukin-2 receptor β chain gene: generation of three receptor forms by cloned human α and β chain cDNA's. Science 244:551.
26. Hohmann, H.-p., M. Brockhaus, P. A. Baeuerle, R. Remy, R. Kolbec, A. P. G. M. van Loon. 1990. Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-κB. J. Biol. Chem. 265:22409.
27. Engelmann, H., H. Holtmann, C. Brakebusch, Y. S. Avni, I. Sarov, Y. Nophar, E. Hadas, O. Leitner, and D. Wallach. 1990. Antibodies to soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. J. Biol. Chem. 265:14497.
28. Espevik, T., M. Brockhaus, H. Loetscher, U. Nonstad, and R. Shalaby. 1990. Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor. J. Exp. Med. 171:415.
29. Shalaby, M. R., A. Sundan, H. Loescher, M. Brockhaus, W. Lasslauer, and T. Espevik. 1990. Binding and regulation of cellular functions by monoclonal antibodies against human tumor necrosis factor receptors. J. Exp. Med. 172:1517.
30. Tartaglia, L. A., R. F. Weber, I. S. Figari, C. Reynolds, M. A. Palladino, Jr., and D. V. Goeddel. 1991. The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl. Acad. Sci. USA 88:9292.
31. Van Zee, K. J., T. Kohno, E. Fischer, C. S. Rock, L. L. Moldawer, and S. F. Lowry. 1992. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor a in vitro and in vivo. Proc. Natl. Acad. Sci. USA 89:4845.
32. Smith, M., W. E. Munger, H.-f. Kung, L. Takacs, and S. K. Durum. 1990. Direct evidence for an intracellular role for TNFα: microinjection of TNF kills target cells. J. Immunol. 144:162.
33. Aggarwal, B. B., T. E. Eessalu, and P. E. Hass. 1985. Characterization of receptors for human tumor necrosis factor and their regulation by γ-interferon. Nature 318:665.
34. Aggarwal, B. B., and T. E. Eessalu. 1987. Induction of receptors for tumor necrosis factor-α by interferons is not a major mechanism for their synergistic cytotoxic response. J. Biol. Chem. 262:10000.
35. Higuchi, M., and B. B. Aggarwal. 1992. Microtiter plate radioreceptor assay for tumor necrosis factor and its receptors in large numbers of samples. Anal. Biochem. 204:53.
36. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, p. 188.
37. Tartaglia, L. A., and D. V. Goeddel. 1992. Tumor necrosis factor receptor signaling. J. Biol. Chem. 267:4304.
38. Brakebusch, C., Y. Nophar, O. Kemper, H. Engelman, and D. Wallach. 1992. Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. EMBO J. 11:943.
39. Engelberts, I., A. Moller, J. F. M. Leeuwenberg, C. van der Linden, and W. A. Buurman. 1992. Administration of TNF inhibitors after exposure to TNF prevents development of the maximal biological effect: an argument for clinical trials with TNF inhibitors. J. Surg. Res. 53, 510.