Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan

Journal of Neuroscience

Volumn 14, Issue 12, 1994, Pages 7616-7628

  Dou, Chang Lin ^a   Levine, Joel M ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

axonal growth; cell adhesion molecule; chondroitin sulfate glycosaminoglycan; chondroitin sulfate proteoglycan; L1; laminin

Indexed keywords

CHONDROITIN SULFATE; GLYCOPROTEIN; GLYCOSAMINOGLYCAN; LAMININ; MONOCLONAL ANTIBODY; N ACETYLGALACTOSAMINE 4 SULFATASE; POLYCLONAL ANTIBODY; PROTEOGLYCAN;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; CEREBELLUM; GLIA CELL; GRANULE CELL; GROWTH INHIBITION; NERVE CELL GROWTH; NERVE FIBER; NERVE FIBER REGENERATION; NERVOUS SYSTEM DEVELOPMENT; NEURITE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; STEM CELL;

EID: 0028091766     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.14-12-07616.1994     Document Type: Article

References (62)

1. Altman J (1972) Postnatal development of the cerebellar cortex in the rat. I. The external germinal layer and the transitional molecular layer. J Comp Neurol 145:353-398.
2. Appel F, Holm J, Conscience J-F, Schachner M (1993) Several extracellular domains of the neural cell adhesion molecule L1 are involved in neurite outgrowth and cell body adhesion. J Neurosci 13:4764-4775.
3. Bixby JL (1989) Protein kinase C is involved in laminin stimulation of neurite outgrowth. Neuron 3:287-297.
4. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72:248-254.
5. Caroni P, Schwab ME (1988a) Two membrane protein fractions from rat central myelin with inhibitory properties for neunte growth and flbroblast spreading. J Cell Biol 106:1281-1288.
6. Caroni P, Schwab ME (1988b) Antibody against myelin-associated inhibitor of neunte growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron 1:85-96.
7. Cole GJ, McCabe CF (1991) Identification of a developmentally regulated keratan sulfate proteoglycan that inhibits cell adhesion and neurite outgrowth. Neuron 7:1007-1018.
8. Davies JA, Cook GMW, Stern CD, Keynes RJ (1990) Isolation from chick somites of a glycoprotein fraction that causes collapse of dorsal root ganglion growth cones. Neuron 4:11-20.
9. Dou CL, Levine JM (1993) Differential effects of glycosaminoglycans on neurite extension on L1 and laminin substrates. Soc Neurosci Abstr 19:1090.
10. Faissner A, Kruse J (1990) J1/tenascin is a repulsive substrate for central nervous system neurons. Neuron 5:627-637.
11. Faissner A, Kruse J, Nieke J, Schachner M (1984) Expression of neural cell adhesion molecule L1 during development in neurological mutants and in the peripheral nervous system. Dev Brain Res 15:69-82.
12. Fawcett JW, Rokos J, Bakst I (1989) Oligodendrocytes repel axons and cause axonal growth cone collapse. J Cell Sci 92:93-100.
13. Felsenfeld DP, Hynes MA, Skoler KM, Furley AJ, Jessel TM (1994) TAG-1 can mediate homophilic binding, but neurite outgrowth on TAG-1 requires an L1-like molecule and β1 integrins. Neuron 12: 675-690.
14. Fichard A, Verna JM, Olivares J, Saxod R (1991) Involvement of chondroitin sulfate proteoglycan in the avoidance of chick epidermis by dorsal root ganglia fibers: a study using β-D-xyloside. Dev Biol 148:1-9.
15. Goodman CS, Shatz CJ (1993) Developmental mechanisms that generate precise patterns of neuronal connectivity. Neuron [Suppl] 10: 77-98.
16. Grumet M, Flaccus A, Margolis RU (1993) Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules. J Cell Biol 120:815-824.
17. Hall DE, Reichardt LF, Crowley E, Holley B, Moezzi H, Sonnenberg A, Damsky CH (1990) The α1/β1 and α6/β1 integrin heterodimers mediate cell attachment to distinct sites on laminin. J Cell Biol 110: 2175-2184.
18. Hascall VC, Heinegard DK, Wight TN (1991) Proteoglycans: metabolism and pathology. In: Cell biology of extracellular matrix (Hay E, ed).
19. Hatten ME (1985) Neuronal regulation of astroglial morphology and proliferation in vitro. J Cell Biol 100:384-396.
20. Herndon ME, Lander AD (1990) A diverse set of developmentally regulated proteoglycans is expressed in the rat central nervous system. Neuron 4:949-961.
21. Hubbard AL, Cohn ZA (1972) The enzymatic iodination of the red cell membrane. J Cell Biol 55:390-405.
22. r 200K/120K integrin heterodimer that binds laminin in a divalent cation-dependent manner. Neuron 1:713-725.
23. Iijima N, Oohira A, Mori T, Kitabatake K, Kohsaka S (1991) Core protein of chondroitin sulfate proteoglycan promotes neurite outgrowth from cultured neocortical neurons. J Neurochem 56:706-708.
24. Klinman DM, Howard JC (1980) Protein iodination suitable for labeling hybridoma antibodies. In: Monoclonal antibodies (Kennett RH, et al., eds), pp 401-402.
25. Kuhn TB, Stoeckli ET, Condrau MA, Rathjen FG, Sonderegger P (1991) Neurite outgrowth on immobilized axonin-1 is mediated by a heterophilic interaction with L1 (G4). J Cell Biol 115:1113-1126.
26. Lafont F, Rouget M, Triller A, Prochiantz A, Rousselet A (1992) In vitro control of neuronal polarity by glycosaminoglycans. Development 114:17-29.
27. Lagenaur C, Lemmon V (1987) An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc Natl Acad Sci USA 84:7753-7757.
28. Lander AD, Fujii DK, Reichardt LF (1985a) Laminin is associated with the "neurite outgrowth-promoting factors" found in conditioned medium. Proc Natl Acad Sci USA 82:2183-2187.
29. Lander AD, Fujii SK, Reichardt LF (1985b) Purification of a factor that promotes neurite outgrowth: isolation of laminin and associated molecules. J Cell Biol 101:898-913.
30. Lemmon V, Farr KL, Lagenaur C (1989) L1-mediated axon outgrowth occurs via a homophilic binding mechanism. Neuron 2:1597-1603.
31. Lemmon V, Burden SM, Payne HR, Elmslie GJ, Hlavin ML (1992) Neurite outgrowth on different substrates: permissive versus instructive influences and the role of adhesive strength. J Neurosci 12:818-826.
32. Letourneau PC, Madsen AM, Palm SL, Furcht LT (1988) Immunoreactivity for laminin in the developing ventral longitudinal pathway of the brain. Dev Biol 125:135-144.
33. Levine JM (1994) Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury. J Neurosci, in press.
34. Levine JM, Card JP (1987) Light and electron microscopic localization of a cell surface antigen (NG2) in the rat cerebellum: association with smooth protoplasmic astrocytes. J Neurosci 7:2711-2720.
35. Levine JM, Stallcup WB (1987) Plasticity of developing cerebellar cells in vitro studied with antibodies against the NG2 antigen. J Neurosci 7:2721-2731.
36. Levine JM, Stincone F, Lee YS (1993) Development and differentiation of glial precursor cells in the rat cerebellum. Glia 7:307-321.
37. Luo Y, Raible D, Raper JA (1993) Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75: 217-227.
38. MacSween JM, Eastwood SL (1978) Recovery of immunologically active antigen from staphylococcal protein A-antibody adsorbent. J Immunol Methods 23:259-267.
39. Maeda N, Matsui F, Oohira A (1992) A chondroitin sulfate proteoglycan that is developmentally regulated in the cerebellar mossy fiber system. Dev Biol 151:564-574.
40. Nishiyama A, Dahlin KJ, Prince JT, Johnstone SR, Stallcup WB (1991) The primary structure of NG2, a novel membrane-spanning proteoglycan. J Cell Biol 114:359-371.
41. Oohira A, Matsui F, Katoh-Semba R (1991) Inhibitory effects of brain chondroitin sulfate proteoglycans on neurite outgrowth from PC12D cells. J Neurosci 11:822-827.
42. Patterson PH (1988) On the importance of being inhibited, or saying no to growth cones. Neuron 1:263-267.
43. Pesheva P, Spiess E, Schachner M (1989) J1-160 and J1-180 are oligodendrocyte-secreted non-permissive substrates for cell adhesion. J Cell Biol 109:1765-1778.
44. Pesheva P, Gennarini G, Goridis C, Schachner M (1993) The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein J1-160/180. Neuron 10:69-82.
45. Pettway Z, Guillory G, Bronner-Fraser M (1990) Absence of neural crest cells from the region surrounding implanted notochords in situ. Dev Biol 142:335-345.
46. Rauch U, Laina K, Maurel P, Margolis RU, Margolis RK (1992) Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain. J Biol Chem 267:19536-19547.
47. Riopelle RJ, Dow KE (1990) Functional interactions of neuronal heparan sulphate proteoglycans with laminin. Brain Res 525:92-100.
48. Rogers SL, Edson KL, Letourneau PC, McLoon SC (1986) Distribution of laminin in the developing peripheral nervous system of the chick. Dev Biol 113:429-435.
49. Rutishauser U, Jessell TM (1988) Cell adhesion molecules in vertebrate neural development. Physiol Rev 68:819-857.
50. Sanes JR (1989) Extracellular matrix molecules that influence neural development. Annu Rev Neurosci 12:491-516.
51. Schubert D, Heinemann S, Carlisle W, Tarikas H, Kimes B, Patrick J, Steinbach J, Gulp W, Brandt B (1974) Clonal cell lines from the rat central nervous system. Nature 249:224-227.
52. Schuch U, Lohse MJ, Schachner M (1989) Neural cell adhesion molecules influence second messenger systems. Neuron 3:13-20.
53. Skubitz APN, McCarthy JB, Charonis AS, Furcht LT (1988) Localization of three distinct heparin-binding domains of laminin by monoclonal antibodies. J Biol Chem 263:4861-4868.
54. Skubitz APN, Letourneau PC, Wayner E, Furcht LT (1991) Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the 1 integrin subunit. J Cell Biol 115:1137-1148.
55. Snow DM, Lemmon V, Carrino DA, Caplan AI, Silver J (1990) Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro. Exp Neurol 109:111-130.
56. Stallcup WB, Beasley L, Levine JM (1983) Cell surface molecules that characterize different stages in the development of cerebellar interneurons. Cold Spring Harbor Symp Quant Biol 48:761-774.
57. Stallcup WB, Beasley L, Levine JM (1985) Antibody against nerve growth factor-inducible large external (NILE) glycoprotein labels nerve fiber tracts in the developing rat nervous system. J Neurosci 5:1090-1101.
58. Stallcup WB, Dahlin K, Healy P (1990) Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen. J Cell Biol 111: 3177-3188.
59. Walter J, Henke-Fahle S, Bonhoeffer F (1987) Avoidance of posterior tectal membranes by temporal retinal axons. Development 101:909-913.
60. Werz W, Schachner M (1988) Adhesion of neural cells to extracellular matrix constituents. Involvement of glycosaminoglycans and cell adhesion molecules. Dev Brain Res 43:225-234.
61. Wilson SS, Baetge EE, Stallcup WB (1981) Antisera specific for cell lines with mixed neuronal and glial properties. Dev Biol 83:146-153.
62. Zaremba S, Guimararaes A, Kalb RG, Hockfield S (1989) Characterization of an activity-dependent, neuronal surface proteoglycan identified with monoclonal antibody Cat-301. Neuron 2:1207-1219.