-
1
-
-
0015694748
-
A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and giemsa staining
-
Rowley, J.D. 1973. A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and giemsa staining. Nature (Lond.). 243:290.
-
(1973)
Nature (Lond.).
, vol.243
, pp. 290
-
-
Rowley, J.D.1
-
2
-
-
0019455210
-
Evidence for a multi-step pathogenesis of chronic myelogenous leukemia
-
Fialkow, P.J., P.J. Martin, V. Najfeld, G.K. Penfold, R.J. Jacobson, and J.A. Hansen. 1981. Evidence for a multi-step pathogenesis of chronic myelogenous leukemia. Blood. 58:158.
-
(1981)
Blood
, vol.58
, pp. 158
-
-
Fialkow, P.J.1
Martin, P.J.2
Najfeld, V.3
Penfold, G.K.4
Jacobson, R.J.5
Hansen, J.A.6
-
4
-
-
0021674862
-
An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity
-
Konopka, J.B., S.M. Watanabe, and O.N. Witte. 1984. An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell. 37:1035.
-
(1984)
Cell
, vol.37
, pp. 1035
-
-
Konopka, J.B.1
Watanabe, S.M.2
Witte, O.N.3
-
5
-
-
0021926819
-
The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity
-
Kloetzer, W., R. Kurzrock, L. Smith, M. Talpaz, M. Speller, J. Gutterman, and R. Arlinghaus. 1985. The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity. Virology. 140:230.
-
(1985)
Virology
, vol.140
, pp. 230
-
-
Kloetzer, W.1
Kurzrock, R.2
Smith, L.3
Talpaz, M.4
Speller, M.5
Gutterman, J.6
Arlinghaus, R.7
-
6
-
-
0023696474
-
Selective transformation of primitive lymphoid cells by the BCR-ABL oncogene expressed in long-term lymphoid or myeloid cultures
-
Young, J.C., and O.N. Witte. 1988. Selective transformation of primitive lymphoid cells by the BCR-ABL oncogene expressed in long-term lymphoid or myeloid cultures. Mol. Cell Biol. 8:4079.
-
(1988)
Mol. Cell Biol.
, vol.8
, pp. 4079
-
-
Young, J.C.1
Witte, O.N.2
-
7
-
-
0001044842
-
Transformation of an interleukin-3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific p210bcr/abl protein
-
Daley, G.Q., and D. Baltimore. 1988. Transformation of an interleukin-3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific p210bcr/abl protein. Proc. Natl. Acad. Sci. USA. 85:9312.
-
(1988)
Proc. Natl. Acad. Sci. USA.
, vol.85
, pp. 9312
-
-
Daley, G.Q.1
Baltimore, D.2
-
8
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
-
Daley, G.Q., R.A. Van Etten, and D. Baltimore. 1990. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science (Wish. DC). 247:824.
-
(1990)
Science (Wish. DC).
, vol.247
, pp. 824
-
-
Daley, G.Q.1
Van Etten, R.A.2
Baltimore, D.3
-
9
-
-
0025127704
-
Murine models for human chronic myelogenous leukemia
-
Rosenberg, N. 1990. Murine models for human chronic myelogenous leukemia. Cancer Cells (Cold Spring Harbor). 2:284.
-
(1990)
Cancer Cells (Cold Spring Harbor)
, vol.2
, pp. 284
-
-
Rosenberg, N.1
-
10
-
-
0026666779
-
Clonal evolution in a myeloid cell line transformed to interleukin-3 independent growth by retroviral transduction and expression of p210bcr/abl
-
Laneuville, P., G. Sun, M. Timm, and M. Vekemans. 1992. Clonal evolution in a myeloid cell line transformed to interleukin-3 independent growth by retroviral transduction and expression of p210bcr/abl. Blood. 80:1788.
-
(1992)
Blood
, vol.80
, pp. 1788
-
-
Laneuville, P.1
Sun, G.2
Timm, M.3
Vekemans, M.4
-
11
-
-
0023715225
-
Inhibition of NIH3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP
-
Feig, L.A., and G.M. Cooper. 1988. Inhibition of NIH3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol. 8:3235.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 3235
-
-
Feig, L.A.1
Cooper, G.M.2
-
12
-
-
0025184759
-
Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH3T3 cells
-
Cai, H., J. Szeberenyi, and G.M. Cooper. 1990. Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH3T3 cells. Mol. Cell. Biol. 10:5314.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 5314
-
-
Cai, H.1
Szeberenyi, J.2
Cooper, G.M.3
-
13
-
-
0026336517
-
Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes
-
Stacey, D.W., M. Roudebuch, R. Day, S.D. Mosser, J.B. Gibbs, and L.A. Feig. 1991. Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes. Oncogene. 6:2297.
-
(1991)
Oncogene
, vol.6
, pp. 2297
-
-
Stacey, D.W.1
Roudebuch, M.2
Day, R.3
Mosser, S.D.4
Gibbs, J.B.5
Feig, L.A.6
-
14
-
-
0027296354
-
Role of p21ras in p210bcr-abl transformation of murine myeloid cells
-
Mandanas, R.A., D.S. Leibowitz, K. Gharehbaghi, T. Tauchi, G.S. Burgess, K. Miyazawa, H.N. Jayaram, and H.S. Boswell. 1993. Role of p21ras in p210bcr-abl transformation of murine myeloid cells. Blood. 82:1838.
-
(1993)
Blood
, vol.82
, pp. 1838
-
-
Mandanas, R.A.1
Leibowitz, D.S.2
Gharehbaghi, K.3
Tauchi, T.4
Burgess, G.S.5
Miyazawa, K.6
Jayaram, H.N.7
Boswell, H.S.8
-
15
-
-
0025838675
-
Regulators and effectors of ras proteins
-
Bollag, G., and F. McCormick. 1991. Regulators and effectors of ras proteins. Annu. Rev. Cell Biol. 7:601.
-
(1991)
Annu. Rev. Cell Biol.
, vol.7
, pp. 601
-
-
Bollag, G.1
McCormick, F.2
-
16
-
-
0027393408
-
The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras-Asn-17
-
Schweighoffer, F., H. Cai, M.C. Chevallier-Multon, I. Fath, G. Cooper, and B. Tocque. 1993. The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras-Asn-17. Mol. Cell. Biol. 13:39.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 39
-
-
Schweighoffer, F.1
Cai, H.2
Chevallier-Multon, M.C.3
Fath, I.4
Cooper, G.5
Tocque, B.6
-
17
-
-
0025605344
-
The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily
-
Aroian, R.V., M. Koga, J.E. Mendel, Y. Ohshima, and P.W. Sternberg. 1990. The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily. Nature (Lond.). 348:693.
-
(1990)
Nature (Lond.).
, vol.348
, pp. 693
-
-
Aroian, R.V.1
Koga, M.2
Mendel, J.E.3
Ohshima, Y.4
Sternberg, P.W.5
-
18
-
-
0025997867
-
Ras 1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
-
Simon, M.A., D.D.L. Bowtell, G.S. Dodson, T.R. Laverty, and G.M. Rubin. 1991. Ras 1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell. 67:701.
-
(1991)
Cell
, vol.67
, pp. 701
-
-
Simon, M.A.1
Bowtell, D.D.L.2
Dodson, G.S.3
Laverty, T.R.4
Rubin, G.M.5
-
19
-
-
0026608238
-
The son of sevenless gene product: A putative activator of Ras
-
Bonfini, L., C.A. Karlovich, C. Dasgupta, and U. Banerjee. 1992. The son of sevenless gene product: a putative activator of Ras. Science (Wash. DC). 255:603.
-
(1992)
Science (Wash. DC).
, vol.255
, pp. 603
-
-
Bonfini, L.1
Karlovich, C.A.2
Dasgupta, C.3
Banerjee, U.4
-
20
-
-
0026729382
-
The SH2 and SH3 domain-containing protein Grb2 links receptor tyrosine kinases to ras signaling
-
Lowenstein, E.J., R.J. Daly, A.G. Batzer, W.L. Margolis, R. Lammers, A. Ullrich, E.Y. Skolnik, D. Bar-Sagi, and j. Schles-singer. 1992. The SH2 and SH3 domain-containing protein Grb2 links receptor tyrosine kinases to ras signaling. Cell. 70:431.
-
(1992)
Cell
, vol.70
, pp. 431
-
-
Lowenstein, E.J.1
Daly, R.J.2
Batzer, A.G.3
Margolis, W.L.4
Lammers, R.5
Ullrich, A.6
Skolnik, E.Y.7
Bar-Sagi, D.8
Schles-Singer, J.9
-
21
-
-
0027910431
-
Association of Sos ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
-
Egan, S.E., B.W. Giddings, M.W. Brooks, L. Buday, A.M. Sizeland, and R.A. Weinberg. 1993. Association of Sos ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature (Lond.). 363:45.
-
(1993)
Nature (Lond.).
, vol.363
, pp. 45
-
-
Egan, S.E.1
Giddings, B.W.2
Brooks, M.W.3
Buday, L.4
Sizeland, A.M.5
Weinberg, R.A.6
-
22
-
-
0027294981
-
The SFI2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the ras activator in Sos 1
-
Rozakis-Adcock, M., R. Fernley, J. Wade, T. Pawson, and D. Bowtell. 1993. The SFI2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the ras activator in Sos 1. Nature (Lond.). 363:83.
-
(1993)
Nature (Lond.).
, vol.363
, pp. 83
-
-
Rozakis-Adcock, M.1
Fernley, R.2
Wade, J.3
Pawson, T.4
Bowtell, D.5
-
23
-
-
0027312272
-
Guanine-nucleotide-releasing factor hSosl binds to Grb2 and links receptor tyrosine kinases to ras signaling
-
Li, N., A. Batzer, R. Daly, Y. Yajnik, E. Skolnik, P. Chardin, D. Bar-Sagi, B. Margolis, and j. Schlessinger. 1993. Guanine-nucleotide-releasing factor hSosl binds to Grb2 and links receptor tyrosine kinases to ras signaling. Nature (Lond.). 363:85.
-
(1993)
Nature (Lond.).
, vol.363
, pp. 85
-
-
Li, N.1
Batzer, A.2
Daly, R.3
Yajnik, Y.4
Skolnik, E.5
Chardin, P.6
Bar-Sagi, D.7
Margolis, B.8
Schlessinger, J.9
-
24
-
-
0027229556
-
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on ras
-
Gale, N.W., S. Kaplan, E.J. Lowenstein, J. Schlessinger, and D. Bar-Sagi. 1993. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on ras. Nature (Lond.). 363:88.
-
(1993)
Nature (Lond.).
, vol.363
, pp. 88
-
-
Gale, N.W.1
Kaplan, S.2
Lowenstein, E.J.3
Schlessinger, J.4
Bar-Sagi, D.5
-
25
-
-
0027153103
-
Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adaptor protein, and Sos nucleotide exchange factor
-
Buday, L., and j. Downward. 1993. Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adaptor protein, and Sos nucleotide exchange factor. Cell. 73:611.
-
(1993)
Cell
, vol.73
, pp. 611
-
-
Buday, L.1
Downward, J.2
-
26
-
-
0027304731
-
Human Sosl: A guanine nucleotide exchange factor for ras that binds to Grb2
-
Chardin, P., J.H. Camonis, N.W. Gale, L.V. Aelst, J. Schlessinger, M.H. Wigler, and D. Bar-Sagi. 1993. Human Sosl: a guanine nucleotide exchange factor for ras that binds to Grb2. Science (Wash. DC). 260:1338.
-
(1993)
Science (Wash. DC).
, vol.260
, pp. 1338
-
-
Chardin, P.1
Camonis, J.H.2
Gale, N.W.3
Aelst, L.V.4
Schlessinger, J.5
Wigler, M.H.6
Bar-Sagi, D.7
-
27
-
-
0026777369
-
A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction
-
Pelicci, G., L. Lanffancone, F. Grignani, J. McGlade, F. Cavallo, G. Forni, I. Nicoletti, F. Grignani, T. Pawson, and P.G. Pelicci. 1992. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell. 70:93.
-
(1992)
Cell
, vol.70
, pp. 93
-
-
Pelicci, G.1
Lanffancone, L.2
Grignani, F.3
McGlade, J.4
Cavallo, F.5
Forni, G.6
Nicoletti, I.7
Grignani, F.8
Pawson, T.9
Pelicci, P.G.10
-
28
-
-
0026678172
-
Association of the She and Grb2/Sem-5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
-
Rozakis-Adcock, M., J. McGlade, G. Mbamalu, G. Pelicci, R. Daly, W. Li, A. Batzer, S. Thomas, J. Brugge, P.G. Pellicci, et al. 1992. Association of the She and Grb2/Sem-5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature (Lond.). 360:689.
-
(1992)
Nature (Lond.).
, vol.360
, pp. 689
-
-
Rozakis-Adcock, M.1
McGlade, J.2
Mbamalu, G.3
Pelicci, G.4
Daly, R.5
Li, W.6
Batzer, A.7
Thomas, S.8
Brugge, J.9
Pellicci, P.G.10
-
29
-
-
0026767469
-
She proteins are phosphorylated and regulated by the v-Src and v-Fps protein tyrosine kinases
-
McGlade, J., A. Cheng, G. Pelicci, P.G. Pelicci, and T. Pawson. 1992. She proteins are phosphorylated and regulated by the v-Src and v-Fps protein tyrosine kinases. Proc. Natl. Acad. Sci. USA. 89:8869.
-
(1992)
Proc. Natl. Acad. Sci. USA.
, vol.89
, pp. 8869
-
-
McGlade, J.1
Cheng, A.2
Pelicci, G.3
Pelicci, P.G.4
Pawson, T.5
-
30
-
-
0026808782
-
BCR/ABL confers growth factor independence upon a murine myeloid cell line
-
Mandanas, R.A., H.S. Boswell, L. Lu, and D. Leibowitz. 1992. BCR/ABL confers growth factor independence upon a murine myeloid cell line. Leukemia. 6:796.
-
(1992)
Leukemia
, vol.6
, pp. 796
-
-
Mandanas, R.A.1
Boswell, H.S.2
Lu, L.3
Leibowitz, D.4
-
31
-
-
0026739347
-
Recombinant human interleukin-9 induces protein tyrosine phosphorylation and syn-ergizes with Steel factor to stimulate proliferation of the human factor-dependent cell line, M07e
-
Miyazawa, K., P. Hendrie, Y.J. Kim, C. Mantel, Y.-C. Yang, B.S. Kwon, and H.E. Broxmeyer. 1992. Recombinant human interleukin-9 induces protein tyrosine phosphorylation and syn-ergizes with Steel factor to stimulate proliferation of the human factor-dependent cell line, M07e. Blood. 80:1685.
-
(1992)
Blood
, vol.80
, pp. 1685
-
-
Miyazawa, K.1
Hendrie, P.2
Kim, Y.J.3
Mantel, C.4
Yang, Y.-C.5
Kwon, B.S.6
Broxmeyer, H.E.7
-
32
-
-
0027466903
-
Insulin-induced phosphorylation of the 46- and 52-KD She proteins
-
Pronk, G.J., J. McGlade, G. Pelicci, T. Pawson, and J.L. Bos. 1993. Insulin-induced phosphorylation of the 46- and 52-KD She proteins. J. Biol. Chem. 268:5748.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5748
-
-
Pronk, G.J.1
McGlade, J.2
Pelicci, G.3
Pawson, T.4
Bos, J.L.5
-
33
-
-
0027401986
-
Epidermal growth factor stimulates the tyrosine phosphorylation of SHC in the mouse
-
Ruff-Jamison, S., J. McGlade, T. Pawson, K. Chen, and S. Cohen. 1993. Epidermal growth factor stimulates the tyrosine phosphorylation of SHC in the mouse. J. Biol. Chem. 268:7610.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7610
-
-
Ruff-Jamison, S.1
McGlade, J.2
Pawson, T.3
Chen, K.4
Cohen, S.5
-
34
-
-
0027288587
-
The SH2/SH3 domain-containing protein Grb2 interacts with tyrosine-phosphorylated IRS1 and She: Implications for insulin control of ras signaling
-
Skolink, E.Y., C.H. Lee, A. Batzer, L.M. Vicentini, M. Zhou, R. Daly, M.J. Myers, Jr., J.M. Backer, A. Ullrich, M.F. White, and J. Schlessinger. 1993. The SH2/SH3 domain-containing protein Grb2 interacts with tyrosine-phosphorylated IRS1 and She: implications for insulin control of ras signaling. EMBO (Eur. Mol. Biol. Organ.) J. 12:1929.
-
(1993)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.12
, pp. 1929
-
-
Skolink, E.Y.1
Lee, C.H.2
Batzer, A.3
Vicentini, L.M.4
Zhou, M.5
Daly, R.6
Myers, M.J.7
Backer, J.M.8
Ullrich, A.9
White, M.F.10
Schlessinger, J.11
-
35
-
-
0026781036
-
Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines
-
Druker, B., K. Okuda, U. Matulonis, R. Salgia, T. Roberts, and J.D. Griffin. 1992. Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines. Blood. 79:2215.
-
(1992)
Blood
, vol.79
, pp. 2215
-
-
Druker, B.1
Okuda, K.2
Matulonis, U.3
Salgia, R.4
Roberts, T.5
Griffin, J.D.6
-
37
-
-
0025967106
-
Protein-tyrosine kinases regulate the phosphorylation, protein interaction, subcellular distribution, and activity of p21ras GTPase-activating protein
-
Moran, M.F., P. Polakis, F. McCormic, T. Pawson, and C. Ellis. 1991. Protein-tyrosine kinases regulate the phosphorylation, protein interaction, subcellular distribution, and activity of p21ras GTPase-activating protein. Mol. Cell. Biol. 11:1804.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1804
-
-
Moran, M.F.1
Polakis, P.2
McCormic, F.3
Pawson, T.4
Ellis, C.5
-
38
-
-
0027536793
-
An actin-binding function contributes to transformation by the bcr-abl oncoprotein of Philadelphia chromosome-positive human leukemias
-
McWhirter, J.R., and J.Y.J. Wang. 1993. An actin-binding function contributes to transformation by the bcr-abl oncoprotein of Philadelphia chromosome-positive human leukemias. EMBO (Eur. Mol. Biol. Organ.) J. 12:1533.
-
(1993)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.12
, pp. 1533
-
-
McWhirter, J.R.1
Wang, J.Y.J.2
|