-
5
-
-
0025763419
-
Max: a Helix-Loop-Helix Zipper Protein that Forms a Sequence-Specific DNA-Binding Complex with Myc
-
(1991)
Science
, vol.251
, pp. 1211-1217
-
-
Blackwood1
Eisenman2
-
6
-
-
0025829169
-
Association of Myn, the Murine Homolog of Max, with c-Myc Stimulates Methylation-Sensitive DNA Binding and Ras Cotransformation
-
(1991)
Cell
, vol.65
, pp. 395-407
-
-
Prendergast1
Lawe2
Ziff3
-
8
-
-
0025981310
-
Methylation-Sensitive Sequence-Specific DNA Binding by the c-Myc Basic Region
-
(1991)
Science
, vol.251
, pp. 186-189
-
-
Prendergast1
Ziff2
-
11
-
-
0026665523
-
Transcriptional Activation by the Human c-Myc Oncoprotein in Yeast Requires Interaction with Max
-
of special interest, This paper demonstrates that Myc is a transcription factor that requires dimerization with Max, and that Max homodimers compete with Myc/Max heterodimers for common DNA-binding sites in vivo. Myc/Max dimerization is preferred over Max/Max.
-
(1992)
Nature
, vol.359
, pp. 423-426
-
-
Amati1
Dalton2
Brooks3
Littlewood4
Evan5
Land6
-
12
-
-
0026576604
-
Myc and Max Associate in Vivo
-
of special interest, This paper shows that Max is a stable phosphoprotein which is constitutively expressed in growing and resting cells, and interacts with Myc in cells.
-
(1992)
Genes Dev
, vol.6
, pp. 71-80
-
-
Blackwood1
Luscher2
Eisenman3
-
15
-
-
0026563516
-
max Encodes a Sequence-Specific DNA-Binding Protein and is Not Regulated by Serum Growth Factors
-
of special interest, This paper shows that max mRNA is constitutively expressed in growing and resting cells.
-
(1992)
Oncogene
, vol.7
, pp. 775-779
-
-
Berberich1
Hyde-DeRuyscher2
Espenshade3
Cole4
-
16
-
-
0026554939
-
Casein Kinase II Inhibits the DNA-Binding Activity of Max Homodimers but not Myc/Max Heterodimers
-
(1992)
Genes Dev
, vol.6
, pp. 166-176
-
-
Berberich1
Cole2
-
18
-
-
0026693776
-
Myc Family Oncoproteins Function Through a Common Pathway to Transform Normal Cells in Culture: Cross-Interference by Max and Transacting Dominant Mutants
-
of special interest, The authors demonstrate dose-dependent suppression of myc transforming activity by max (see also [19,21••]). This paper also shows that c-, N-, and L-myc, which all bind Max, compete for common targets in cellular transformation.
-
(1992)
Genes Dev
, vol.6
, pp. 1480-1492
-
-
Mukherjee1
Morgenbesser2
DePinho3
-
20
-
-
11944256565
-
Mutational Analysis of Max: Role of Basic, Helix-Loop-Helix/Leucine Zipper Domains in DNA Binding, Dimerization and Regulation of Myc-Mediated Transcriptional Activation
-
(1992)
Oncogene
, vol.7
, pp. 2085-2092
-
-
Reddy1
Dasgupta2
Saikumar3
Dudek4
Rauscher5
Reddy6
-
21
-
-
0027533679
-
Oncogenic Activity of the c-Myc Protein Requires Dimerization with Max
-
of outstanding interest, This paper shows that Max is the functional partner of Myc in cellular transformation, but that it also suppresses Myc function in a dose-dependent manner (see also [18•,19]).
-
(1993)
Cell
, vol.72
, pp. 233-245
-
-
Amati1
Brooks2
Levy3
Littlewood4
Evan5
Land6
-
26
-
-
0027431276
-
A Switch from Myc:Max to Mad:Max Heterocomplexes Accompanies Monocyte/Macrophage Differentiation
-
of outstanding interest, This paper shows that Mad is an unstable protein, and that its expression is induced during differentiation, in parallel to the disappearance of c-Myc, Max remains stable and is expressed at constant levels in differentiating cells.
-
(1993)
Genes Dev
, vol.7
, pp. 2110-2119
-
-
Ayer1
Eisenman2
-
27
-
-
0028299321
-
Expression of mad, mxi1, max and c-myc During Induced Differentiation of Hematopoietic Cells: Opposite Regulation of Mad and c-myc
-
of special interest, in press, This paper shows that the expression of mad and mxi-1 mRNAs is induced in differentiating cells, while max remains constant and c-myc levels decay.
-
(1994)
Oncogene
-
-
Larsson1
Pettersson2
Oberg3
Nilsson4
Luscher5
-
29
-
-
0026737875
-
Myc and Max Proteins Possess Distinct Transcriptional Activities
-
of special interest, See [30•].
-
(1992)
Nature
, vol.359
, pp. 426-429
-
-
Kretzner1
Blackwood2
Eisenman3
-
30
-
-
0027536102
-
Opposite Regulation of Gene Transcription and Cell Proliferation by c-Myc and Max
-
of special interest, edn 4, This paper and [29•] show that Myc transactivates CACGTG-driven promoters in transient transfection experiments, whereas Max represses such promoters and antagonizes Myc in a dose-dependent manner.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2935-2939
-
-
Gu1
Cechova2
Tassi3
Dalla-Favera4
-
32
-
-
0027459938
-
Sequence-Specific Transcriptional Activation by Myc and Repression by Max
-
(1993)
Mol Cell Biol
, vol.13
, pp. 383-390
-
-
Amin1
Wagner2
Hay3
-
38
-
-
0025298468
-
The Leucine Zipper Domain of Avian c-Myc is Required for Transformation and Autoregulation
-
(1990)
Oncogene
, vol.5
, pp. 683-689
-
-
Crouch1
Lang2
Gillespie3
-
43
-
-
0027364326
-
The c-Myc Protein Induces Cell Cycle Progression and Apoptosis through Dimerization with Max
-
of special interest, This paper shows that induction of cell proliferation and apoptosis by Myc in non-transformed cells requires dimerization with Max.
-
(1993)
EMBO J
, vol.12
, pp. 5083-5087
-
-
Amati1
Littlewood2
Evan3
Land4
-
44
-
-
0027408096
-
Mad: a Heterodimeric Partner for Max that Antagonizes Myc Transcriptional Activity
-
of outstanding interest, Identification of Mad, a bHLHLZ dimerization partner of Max which suppresses transcriptional activation by Myc. Myc and Mad compete for Mad with similar affinities, and Mad/Max dimers bind to Myc/Max DNA target sites.
-
(1993)
Cell
, vol.72
, pp. 211-222
-
-
Ayer1
Kretzner2
Eisenman3
-
45
-
-
0027511606
-
Mxi1, a Protein that Specifically Interacts with Max to Bind Myc-Max Recognition Sites
-
of outstanding interest, Identification of Mxi-1, a bHLHLZ dimerization partner of Max. Mxi-1/Max dimers bind to Myc/Max DNA target sites. The mxi-1 mRNA is induced during differentiation.
-
(1993)
Cell
, vol.72
, pp. 223-232
-
-
Zervos1
Gyuris2
Brent3
-
59
-
-
0025833159
-
Amino-Terminal Domains of c-myc and N-myc Proteins Mediate Binding to the Retinoblastoma Gene Product
-
(1991)
Nature
, vol.352
, pp. 541-544
-
-
Rustgi1
Dyson2
Bernards3
-
63
-
-
0026099022
-
The MYC Protein Activates Transcription of the alpha-Prothymosin Gene
-
(1991)
EMBO J
, vol.10
, pp. 133-141
-
-
Eilers1
Schirm2
Bishop3
-
65
-
-
0025906211
-
Effects of Over-expression of Ornithine Decarboxylase (ODC) on Growth Control and Oncogene-Induced Cell Transformation
-
(1991)
Oncogene
, vol.6
, pp. 739-743
-
-
Hibshoosh1
Johnson2
Weinstein3
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