Bradykinin excites tetrodotoxin-resistant primary afferent fibers

Brain Research

Volumn 665, Issue 1, 1994, Pages 69-76

  Jeftinija, Srdija ^a  

^a Signal Transduction Training Program   (United States)

Author keywords

Bradykinin; Dorsal horn; Intracellular recording; Primary afferent neuron sensitization; Rat; Synaptic plasticity; Tetrodotoxin resistant

Indexed keywords

BRADYKININ; BRADYKININ ANTAGONIST; BRADYKININ DERIVATIVE; BRADYKININ RECEPTOR; DEXTRO ARGINYLBRADYKININ[3 HYDROXYPROLINE 5,8 [3 (2 THIENYL)ALANINE] 7 DEXTRO PHENYLALANINE]; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTRACELLULAR RECORDING; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; TISSUE SLICE;

AFFERENT PATHWAYS; ANIMAL; BRADYKININ; DRUG RESISTANCE; DRUG SYNERGISM; GANGLIA, SPINAL; IN VITRO; NERVE FIBERS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, U.S. GOV'T, P.H.S.; TETRODOTOXIN;

EID: 0028081850     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(94)91153-3     Document Type: Article

References (35)

1. Some rat sensory neurones in culture express characteristics of different pain sensory cells
2. 9-bradykinin with isolated pig coronary arteries: mechanical and electrophysiological events
3. Regulation of kinins: kallikreins, kininoges, and kininases
4. Bradykinin-induced modulation of calcium signals in rat dorsal root ganglion neurons in vitro
5. Bradykinin analogues: different agonist and antagonist activities suggesting multiple receptors
6. The neuropharmacology of capsaicin: review of some recent observations
7. A bradykinin antagonist inhibits carageenan edema in rat
8. Activation of glutamate cyclase by bradykinin in rat sensory neurons is mediated by calcium influx: possible role of the increase in cyclic GMP
9. Suppression of carageenin induced hyperalgesia, hypertermia and edema by a bradykinin antagonist
10. Capsaicin desensitization of peripheral nociceptive fibers does not impair sensitivity to other noxious stimuli
11. Bradykinin-induced activation of nociceptors: receptors and mechanistic studies on the neonatal rat spinal cord-tail preparation in vitro
12. Bradykinin-induced depolarisation of primary afferent nerve terminals in the neonatal rat spinal cord in vitro
13. Identification of B2 bradykinin binding sites in guinea pig brain
14. Electrophysiological evidence for a role of bradykinin in chemical nociception
15. Bradykinin is increased during acute and chronic inflammation: therapeutic implications
16. Bradykinin excites tetrodotoxin-resistant primary afferents
17. The role of tetrodotoxin-resistant sodium channels of small primary afferent fibers
18. The selective activation of dorsal horn neurons by potassium stimulation of high threshold primary afferent neurons in vitro
19. Ionic currents in the somatic membrane of rat dorsal root ganglion neurons I. Sodium currents
20. Intrathecal bradykinin acts presynaptically on spinal noradrenergic terminals to produce antinociception in the rat
21. Chemosensitivity of fine afferents from rat skin in vitro
22. Bradykinin receptor mediated chloride secretion in intestinal function
23. Two bradykinin binding sites with picomolar affinities
24. Novel classes of nociceptors; beyond Sherrington
25. + channels in neurons of the rat dorsal root ganglia
26. Characterization of sodium currents in mammalian sensory neurons cultured in serum-free defined medium with and without nerve growth factor
27. 2+ elevation in neuroblastoma × glioma hybrid NG108-15 cells: relationship to the action of inositol phospholipid metabolites
28. 125I]bradykinin binding sites in guinea pig brain
29. Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin
30. Activation of protein kinase C causes a depolarization of the rat vagus nerve associated with increased sodium conductance
31. Pharmacology of bradykinin and related kinins
32. Identification of B2 receptors in guinea pig brain regions, spinal cord and peripheral tissues
33. Antagonists of B2 bradykinin receptors
34. Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions
35. Inhibition of calcium-dependent spike after-hyperpolarization increases excitability of rabbit visceral sensory neurones