Phage libraries for generation of clinically useful antibodies

The Lancet

Volumn 343, Issue 8895, 1994, Pages 455-456

  Chester, K A ^a   Begent, R H J ^a   Robson, L ^a   Keep, P A ^a   Pedley, R B ^a   Boden LIBiol, J A ^a   Boxer, G ^a   Green, A ^a   Winter, G ^b   Cochet, O ^b   Hawkins, R E ^c  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b Centre for Protein Engineering   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; BACTERIOPHAGE; CANCER; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION; GENE LIBRARY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0028078866     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(94)92695-6     Document Type: Article

References (6)

1. Targeted therapies: cell surface targets
2. Phage antibodies: filamentous phage displaying antibody variable domains
3. Monoclonal antibodies in medicine: adapting antibodies for clinical use
4. Making antibody fragments using phage display libraries
5. Selection of phage antibodies by binding affinity: mimicking affinity maturation
6. Specificity and affinity of monoclonal antibodies against carcinoembryonic antigen