Significance of plaque ulceration in symptomatic patients with high-grade carotid stenosis

Stroke

Volumn 25, Issue 2, 1994, Pages 304-308

  Eliasziw, Michael ^a   Streifler, Jonathan Y ^b   Fox, Allan J ^b   Hacbinski, Vladimir C ^b   Ferguson, Gary G ^c   Barnett, Henry J M ^b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b Department of Clinical Neurological Sciences ^*  (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Carotid endarterectomy; Clinical trials; Prognosis; Stenosis

Indexed keywords

ADULT; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERIOGRAPHY; CAROTID ARTERY OBSTRUCTION; CAROTID ENDARTERECTOMY; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZATION; REGRESSION ANALYSIS; RISK FACTOR; STROKE; ULCER;

CAROTID ARTERY DISEASES; CAROTID STENOSIS; CEREBRAL ANGIOGRAPHY; CEREBROVASCULAR DISORDERS; FEMALE; HUMANS; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; REGRESSION ANALYSIS; RISK FACTORS; ULCER;

EID: 0028078732     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/01.STR.25.2.304     Document Type: Article

References (20)

1. Wechsler LR. Ulceration and carotid artery disease. Stroke. 1988;19:650-653.
2. Imparato AM, Riles TS, Mintzer R, Baumann FG. The importance of hemorrhage in the relationship between gross morphologic characteristics and cerebral symptoms in 376 carotid artery plaques. Ann Surg. 1983;197:195-203.
3. Fisher M, Blumenfeld AM, Smith T. The importance of carotid artery plaque disruption and hemorrhage. Arch Neurol 1987;44:1086-1089.
4. Bornstein NM, Krajewski A, Lewis AJ, Norris JW. Clinical significance of carotid plaque hemorrhage. Arch Neurol. 1990;47:958-959.
5. Cebul RD, Whisnant JP. Carotid endarterectomy.Ann Intern Med. 1989;111:660-670.
6. Moore WS, Hall AD. Ulcerated atheroma of the carotid artery. Am J Surg. 1968;116:237-242.
7. Moore WS, Hall AD. Importance of emboli from carotid bifurcation in pathogenesis of cerebral ischemic attacks. Arch Surg. 1970;101:708-716.
8. Zukowski AJ, Nicolaides AN, Lewis RT, Mansfield AO, Williams MA, Helmis E, Malouf GM, Thomas D, Al-Kutoubi A, Kyprianou P, Eastcott HHG. The correlation between carotid plaque ulceration and cerebral infarction seen on CT scan. J Vase Surg. 1984;l:782-786.
9. Sterpetti AV, Hunter WJ, Schultz RD. Importance of ulceration of carotid plaque in determining symptoms of cerebral ischemia. J Cardiovasc Surg. 1991;32:154-158.
10. Houser OW, Sundt TM Jr, Holman CB, Sandok BA, Burton RC. Atheromatous disease of the carotid artery. J Neurosurg. 1974;41:321-331.
11. Moore WS, Boren C, Malone JM, Roon AJ, Eisenberg R, Goldstone J, Mani R. Natural history of nonstenotic, asymptomatic ulcerative lesions of the carotid artery. Arch Surg. 1978;113:1352-1359.
12. Kroener JM, Dorn PL, Shoor PM, Wickbom IG, Bernstein EF. Prognosis of asymptomatic ulcerating carotid lesions. Arch Surg. 1980;115:1387-1392.
13. Dixon S, Pais SO, Raviola C, Gomes A, Machleder HI, Baker D, Busuttil RW, Barker WF, Moore WS. Natural history of nonstenotic, asymptomatic ulcerative lesions of the carotid artery. Arch Surg. 1982;117:1493-1498.
14. Harward TRS, Kroener JM, Wickbom IG, Bernstein EF. Natural history of asymptomatic ulcerative plaques of the carotid bifurcation. Am J Surg. 1983;146:208-212.
15. Grotta JC, Bigelow RH, Hu H, Hankins L, Fields WS. The significance of carotid stenosis or ulceration. Neurology. 1984;34:437-442.
16. NASCET collaborators. Beneficial effect of carotid endarter-ectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991;325:445-453.
17. Steering Committee of NASCET. North American Symptomatic Carotid Endarterectomy Trial: methods, patient characteristics, and progress. Stroke. 1991;22:711-720.
18. Streifler JY, Eliasziw M, Fox AJ, Benavente OR, Hachinski VC, Ferguson GG, Barnett HJM. Angiographic detection of carotid plaque ulceration: comparison with surgical observations in a mul-ticenter study. Stroke. In press.
19. Dixon WJ, Brown MB, Engelman L, Jennrich RI. BMDP Statistical Software. Berkeley, Calif: University of California Press; 1990: 769-806.
20. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic Research. New York, NY: Van Nostrand Reinhold; 1982:419-491.