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Volumn 54, Issue 22, 1994, Pages 5875-5881

Clinical and Endocrine Effects of the Oral Aromatase Inhibitor Vorozole in Postmenopausal Patients with Advanced Breast Cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANALGESIC AGENT; ANDROSTENEDIONE; AROMATASE; AROMATASE INHIBITOR; CA 15-3 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; ESTRADIOL; ESTROGEN RECEPTOR; ESTRONE; ESTRONE SULFATE; FOLLITROPIN; HYDROCORTISONE; HYDROXYPROGESTERONE; LUTEINIZING HORMONE; OPIATE DERIVATIVE; SEX HORMONE BINDING GLOBULIN; TAMOXIFEN; TESTOSTERONE; THYROTROPIN; THYROXINE; VOROZOLE;

EID: 0028077626     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (65)

References (37)
  • 1
    • 0015321696 scopus 로고
    • Role of hormones in the etiology of breast cancer
    • Muhlblock, O., Role of hormones in the etiology of breast cancer. J. Natl. Cancer Inst. 48: 1213-1220, 1972.
    • (1972) J. Natl. Cancer Inst. , vol.48 , pp. 1213-1220
    • Muhlblock, O.1
  • 2
    • 0018217717 scopus 로고
    • Aminoglutethimide inhibits extraglandular oestrogen production in postmenopausal women with breast carcinoma
    • Santen, R. J., Santner, S., Davis, B. Veldhuis, J., Samojlik, E., and Ruby, E., Aminoglutethimide inhibits extraglandular oestrogen production in postmenopausal women with breast carcinoma. J. Gin. Endocrinol. Metab. 47: 1257-1265, 1978.
    • (1978) J. Gin. Endocrinol. Metab. , vol.47 , pp. 1257-1265
    • Santen, R.J.1    Santner, S.2    Davis, B.3    Veldhuis, J.4    Samojlik, E.5    Ruby, E.6
  • 6
    • 0021712326 scopus 로고
    • 4-hydroxyandrostenedione in treatment of postmenopausal patients with advanced breast cancer
    • Coombes, R. C., Goss, P., Dowsett, M. Gazet, J. C., and Brodie, A.M.H. 4-hydroxyandrostenedione in treatment of postmenopausal patients with advanced breast cancer. Lancet, if: 1237-1239, 1984.
    • (1984) Lancet , pp. 1237-1239
    • Coombes, R.C.1    Goss, P.2    Dowsett, M.3    Gazet, J.C.4    Brodie, A.M.H.5
  • 7
    • 0022471541 scopus 로고
    • Treatment of advanced postmenopausal breast cancer with an aromatase inhibitor, 4-hydroxyandrostenedione: phase II report
    • Goss, P. E., Powles, T. J., Dowsett, M., Hutchinson, G. Brodie, A.M.H. Gazet, J.C., and Coombes, R. C., Treatment of advanced postmenopausal breast cancer with an aromatase inhibitor, 4-hydroxyandrostenedione: phase II report. Cancer Res. 46: 4823-4826, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 4823-4826
    • Goss, P.E.1    Powles, T.J.2    Dowsett, M.3    Hutchinson, G.4    Brodie, A.M.H.5    Gazet, J.C.6    Coombes, R.C.7
  • 8
    • 0025169332 scopus 로고
    • The clinical and endocrine effects of 4-hydroxyandrostenedione alone and in combination with goserelin in premenopausal women with advanced breast cancer
    • Stein, R. C., Dowsett, M., Hedley, A. Gazet, J. C., Ford, H. T., and Coombes, R. C., The clinical and endocrine effects of 4-hydroxyandrostenedione alone and in combination with goserelin in premenopausal women with advanced breast cancer. Br. J. Cancer, 62: 679-683, 1990.
    • (1990) Br. J. Cancer , vol.62 , pp. 679-683
    • Stein, R.C.1    Dowsett, M.2    Hedley, A.3    Gazet, J.C.4    Ford, H.T.5    Coombes, R.C.6
  • 9
    • 0023946980 scopus 로고
    • CGS 16949A, a new nonsteroidal aromatase inhibitor: effects on hormone-dependent and -independent tumors in vivo
    • Schieweck, K., Bhatnager, A. S., and Matter, A., CGS 16949A, a new nonsteroidal aromatase inhibitor: effects on hormone-dependent and -independent tumors in vivo. Cancer Res. 48: 834-838, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 834-838
    • Schieweck, K.1    Bhatnager, A.S.2    Matter, A.3
  • 10
    • 0025274853 scopus 로고
    • Preliminary study of the treatment of advanced breast cancer in postmenopausal women with the aromatase inhibitor CGS 16949A
    • Stein, R. C., Dowsett, M., Davenport, J. Hedley, A., Ford, H. T., Gazet, J. C., and Coombes, R. C., Preliminary study of the treatment of advanced breast cancer in postmenopausal women with the aromatase inhibitor CGS 16949A Cancer Res. 50: 1381-1384, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 1381-1384
    • Stein, R.C.1    Dowsett, M.2    Davenport, J.3    Hedley, A.4    Ford, H.T.5    Gazet, J.C.6    Coombes, R.C.7
  • 12
    • 0024595623 scopus 로고
    • Dose-related endocrine effects and pharmacokinetics of oral and intramuscular 4-hydroxyandostenedione in postmenopausal breast cancer patients
    • Dowsett, M., Cunningham, D. Powles, T. J., Hutchinson, G., Brodie, A.M.H., Ford, H. T., Gazet, J. C., and Coombes, R. C., Dose-related endocrine effects and pharmacokinetics of oral and intramuscular 4-hydroxyandostenedione in postmenopausal breast cancer patients. Cancer Res. 49: 1306-1312, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 1306-1312
    • Dowsett, M.1    Cunningham, D.2    Powles, T.J.3    Hutchinson, G.4    Brodie, A.M.H.5    Ford, H.T.6    Gazet, J.C.7    Coombes, R.C.8
  • 13
    • 0026544537 scopus 로고
    • A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced breast cancer
    • Raats, I. I., Falkson, G., and Falkson, H. C., A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced breast cancer. J. Clin. Oncol. 10: 111-116, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 111-116
    • Raats, I.I.1    Falkson, G.2    Falkson, H.C.3
  • 14
    • 0025327094 scopus 로고
    • Potency and selectivity of the non-steroidal aromatase inhibitor CGS 16949A in postmenopausal breast cancer patients
    • Dowsett, M., Stein, R. C., Mehta, A., and Coombes, R. C., Potency and selectivity of the non-steroidal aromatase inhibitor CGS 16949A in postmenopausal breast cancer patients. Clin. Endocrinol. 32: 623-634, 1990.
    • (1990) Clin. Endocrinol. , vol.32 , pp. 623-634
    • Dowsett, M.1    Stein, R.C.2    Mehta, A.3    Coombes, R.C.4
  • 19
    • 0344948529 scopus 로고
    • Vorozole-racemate (R76713): a specific non-steroidal aromatase inhibitor pilot study in advanced postmenopausal breast cancer
    • Borms, M., Vandebroek, J. Rutten, J., Tytgat, J. DeCoster, R., Langenaeken, C., and Bruynseels, J., Vorozole-racemate (R76713): a specific non-steroidal aromatase inhibitor pilot study in advanced postmenopausal breast cancer. Eur. J. Cancer, 29(A) (Suppl. 6); S84, 1993.
    • (1993) Eur. J. Cancer , vol.29(A) , pp. S84
    • Borms, M.1    Vandebroek, J.2    Rutten, J.3    Tytgat, J.4    DeCoster, R.5    Langenaeken, C.6    Bruynseels, J.7
  • 20
    • 0027443281 scopus 로고
    • Inhibition of the in vivo conversion of androstenedione to estrone by the aromatase inhibitor vorozole in healthy postmenopausal women
    • Van der Wall, E., Donker, T. H., DeFrankrijker, E., Nortier, H.W.R., Thijssen, J.H.H. and Blankenstein, M. A., Inhibition of the in vivo conversion of androstenedione to estrone by the aromatase inhibitor vorozole in healthy postmenopausal women. Cancer Res. 53: 4563-4566, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4563-4566
    • Van der Wall, E.1    Donker, T.H.2    DeFrankrijker, E.3    Nortier, H.W.R.4    Thijssen, J.H.H.5    Blankenstein, M.A.6
  • 24
    • 0009578423 scopus 로고
    • Cancer-related pain and analgesic score
    • EORTC Breast Cancer Co-Operative Group
    • European Organisation for Research and Treatment of Cancer. Cancer-related pain and analgesic score. In: Manual for Clinical Research in Breast Cancer, EORTC Breast Cancer Co-Operative Group, 1991.
    • (1991) Manual for Clinical Research in Breast Cancer
  • 26
    • 0023148339 scopus 로고
    • Use of the aromatase inhibitor 4-hydroxyandrostenedione in postmenopausal breast cancer: optimization of therapeutic dose and route
    • Dowsett, M., Goss, P. E., Powles, T. J., Hutchinson, G., Brodie, A.M.H. Jeffcoate, S. L., and Coombes, R. C., Use of the aromatase inhibitor 4-hydroxyandrostenedione in postmenopausal breast cancer: optimization of therapeutic dose and route. Cancer Res. 47: 1957-1961, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 1957-1961
    • Dowsett, M.1    Goss, P.E.2    Powles, T.J.3    Hutchinson, G.4    Brodie, A.M.H.5    Jeffcoate, S.L.6    Coombes, R.C.7
  • 27
    • 0025015333 scopus 로고
    • A dose-comparative endocrine clinical study of leuporelin in premenopausal breast cancer patients
    • Dowsett, M., Mehta, A. Mansi, J., and Smith, I. E., A dose-comparative endocrine clinical study of leuporelin in premenopausal breast cancer patients. Br. J. Cancer, 62: 834-837, 1990.
    • (1990) Br. J. Cancer , vol.62 , pp. 834-837
    • Dowsett, M.1    Mehta, A.2    Mansi, J.3    Smith, I.E.4
  • 29
    • 0023278380 scopus 로고
    • Long-term adjuvant therapy with tamoxifen: effects on sex hormone binding globulin and antithrombin III
    • Jordan, V. C., Fritz, N. F., and Tormey, D. C., Long-term adjuvant therapy with tamoxifen: effects on sex hormone binding globulin and antithrombin III. Cancer Res. 47: 4517-4519, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 4517-4519
    • Jordan, V.C.1    Fritz, N.F.2    Tormey, D.C.3
  • 30
    • 0026518230 scopus 로고
    • Antitumoral and endocrine effects of (+)-vorozole in rats bearing dimethylbenzanthracene-induced mammary tumors
    • De Coster, R., Van Ginckel, R. F., Callens, M.J.L. Goeminne, N.K.G. and Janssens, B.L.E. Antitumoral and endocrine effects of (+)-vorozole in rats bearing dimethylbenzanthracene-induced mammary tumors. Cancer Res. 52; 1240-1244, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1240-1244
    • De Coster, R.1    Van Ginckel, R.F.2    Callens, M.J.L.3    Goeminne, N.K.G.4    Janssens, B.L.E.5
  • 32
    • 0027535830 scopus 로고
    • Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer
    • Iveson, T. J., Smith, I. E., Ahern, J., Smithers, D. Tninet, P. E., and Dowsett, M., Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer. Cancer Res. 53: 266-270, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 266-270
    • Iveson, T.J.1    Smith, I.E.2    Ahern, J.3    Smithers, D.4    Tninet, P.E.5    Dowsett, M.6
  • 33
    • 0020630614 scopus 로고
    • Endocrine effects of low dose aminoglutethimide alone in advanced postmenopausal breast cancer
    • Harris, A. L., Dowsett, M., Smith, I. E., and Jeffcoate, S. L., Endocrine effects of low dose aminoglutethimide alone in advanced postmenopausal breast cancer. Br. J. Cancer, 47: 621-627, 1983.
    • (1983) Br. J. Cancer , vol.47 , pp. 621-627
    • Harris, A.L.1    Dowsett, M.2    Smith, I.E.3    Jeffcoate, S.L.4
  • 35
    • 0023708345 scopus 로고
    • The definition of the ‘no-change’ category in patients treated with endocrine therapy and chemotherapy for advanced carcinoma of the breast
    • Howell, A., Mackintosh, I., and Jones, M., The definition of the ‘no-change’ category in patients treated with endocrine therapy and chemotherapy for advanced carcinoma of the breast. Eur. J. Cancer Clin. Oncol. 24: 1567-1572, 1988.
    • (1988) Eur. J. Cancer Clin. Oncol. , vol.24 , pp. 1567-1572
    • Howell, A.1    Mackintosh, I.2    Jones, M.3
  • 36
    • 0026666565 scopus 로고
    • 4-Hydroxyandrostenedione: a new treatment for post-menopausal patients with breast cancer
    • 28A
    • Coombes, R. C., Hughes, S.W.M. and Dowsett, M. 4-Hydroxyandrostenedione: a new treatment for post-menopausal patients with breast cancer. Eur. J. Cancer, 28A: 1941-1945, 1992.
    • (1992) Eur. J. Cancer , pp. 1941-1945
    • Coombes, R.C.1    Hughes, S.W.M.2    Dowsett, M.3
  • 37
    • 84969040818 scopus 로고
    • Oestrogen receptor expression and function in tamoxifen resistant breast cancer
    • Johnston, S.R.D. Smith, I. E., King, N., and Dowsett, M., Oestrogen receptor expression and function in tamoxifen resistant breast cancer. Breast, 2: 193, 1993.
    • (1993) Breast , vol.2 , pp. 193
    • Johnston, S.R.D.1    Smith, I.E.2    King, N.3    Dowsett, M.4


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