Familial risks for Alzheimer disease from a population‐based series

Genetic Epidemiology

Volumn 11, Issue 4, 1994, Pages 365-374

  Hirst, C ^a   Yee, I M L ^a   Sadovnick, A D ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

age specific risks; lifetime risk estimates; risk counseling

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; AUTOSOMAL DOMINANT DISORDER; DEMENTIA; DIAGNOSTIC ACCURACY; DISEASE PREDISPOSITION; DISEASE TRANSMISSION; FAMILIAL DISEASE; FEMALE; GENETIC COUNSELING; GENETIC MODEL; HIGH RISK POPULATION; HUMAN; INFORMATION PROCESSING; LIFESPAN; MAJOR CLINICAL STUDY; MALE; RISK ASSESSMENT;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BIAS (EPIDEMIOLOGY); BRITISH COLUMBIA; COMPARATIVE STUDY; CROSS-SECTIONAL STUDIES; EPIDEMIOLOGY, MOLECULAR; FEMALE; GENES, DOMINANT; GENETICS, POPULATION; HUMAN; INCIDENCE; LONGITUDINAL STUDIES; MALE; MODELS, GENETIC; MORBIDITY; PEDIGREE; POPULATION SURVEILLANCE; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SUPPORT, NON-U.S. GOV'T;

EID: 0028077454     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.1370110406     Document Type: Article

References (42)

1. The family history using diagnostic criteria: reliability and validity
2. Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham study
3. Differential behaviourial effects in frontal lobe disease
4. Familial Alzheimer's disease in American descendants of Volga Germans: probable genetic founder effect
5. Familial Alzheimer's dementia: a prevalent disorder with pecific clinical features
6. Criteria for onset critically influence the estimation of familial risk in Alzheimer's disease
7. Familial aggregation in Alzheimer's disease: comparison of risk among first degree relatives of early and late‐onset cases, and among male and female relatives in a successive generation
8. Accuracy of clinical diagnosis of Alzheimer's disease
9. Cued recall in amnesia
10. Early‐onset Alzheimer's Disease caused by a mutation at codon 717 of the β‐amyloid precursor protein gene
11. Clinical subtypes of dementia of the Alzheimer type
12. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
13. A multi‐focus assessment scale for use with frail elderly populations
14. The genetics of Alzheimer's disease: a review and a discussion of the implications
15. Assessment of genetic risk for Alzheimer's disease among first‐degree relatives
16. Reliability of clinical criteria for the diagnosis of dementia
17. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's Disease
18. Familial Alzheimer's disease in two kindreds of the same geographic and ethnic origin: a clinical and genetic study
19. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β‐amyloid precursor protein gene
20. Risk of dementia in relatives of patients with Alzheimer's disease
21. Non‐parametric estimations from incomplete observations
22. Molecular and prospective phenotypic characterization of a pedigree with FAD and a missense mutation in codon 717 of the β‐amyloid precursor protein gene
23. Alzheimer disease: basic and clinical advances
24. A family‐genetic study of dementia of the Alzheimer type
25. Risk of dementia in first‐degree relatives of patients with Alzheimer's disease and related disorders
26. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease
27. Alzheimer's disease. Morbid risk among first degree‐relatives approximates 50% by 90 years of age
28. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N‐terminus of β‐amyloid
29. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's Disease
30. Genetic linkage studies in Alzheimer's disease families
31. Familial Alzheimer's disease
32. Genetic studies on an Alzheimer Clinic population
33. Association of apolipoproteins E allele E4 with late‐onset familial and sporadic Alzheimer disease
34. Reliability of the family history method in genetic studies of Alzheimer's disease and related dementias
35. The NINCDS‐ADRDA Work Group criteria for the clinical diagnosis of Alzheimer's disease: a clinicopathologic study of 57 cases
36. Cued recall and dementia
37. Cued recall and early identification of dementia
38. The psychological consequences of predictive testing for Huntington's disease