High-performance liquid chromatography and photoaffinity crosslinking to explore the binding environment of nevirapine to reverse transcriptase of human immunodeficiency virus type-1

Journal of Chromatography A

Volumn 676, Issue 1, 1994, Pages 99-112

  Palladino, Deborah E H ^a   Hopkins, Jerry L ^a   Ingraham, Richard H ^a   Warren, Thomas C ^a   Kapadia, Suresh R ^a   Van Moffaert, Glenn J ^a   Grob, Peter M ^a   Stevenson, James M ^a   Cohen, Kenneth A ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEVIRAPINE; RNA DIRECTED DNA POLYMERASE;

AMINO ACID SEQUENCE; BINDING AFFINITY; BINDING SITE; CONFERENCE PAPER; CROSS LINKING; ENZYME ACTIVITY; ENZYME STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS 1; PEPTIDE MAPPING; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

AFFINITY LABELS; AZEPINES; BENZODIAZEPINONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMAN; NEVIRAPINE; PEPTIDE MAPPING; PHOTOCHEMISTRY; PYRIDINES; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; SEQUENCE ANALYSIS; SPECTROPHOTOMETRY, ULTRAVIOLET; TRYPSIN;

EID: 0028076791     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9673(94)80458-3     Document Type: Article

References (52)

1. and the ddC Study Group of the AIDS Clinical Trials Group