Synthesis and inhibitory activity of difluoroketone substrate analogs of N-myristoyltransferase.

Tetrahedron

Volumn 50, Issue 33, 1994, Pages 9847-9864

  Neder, Karen M ^a   French, Stephanie A ^a   Miller, Stephen P F ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; COENZYME A DERIVATIVE; ENZYME INHIBITOR; ORGANOFLUORINE DERIVATIVE; PROTEIN N MYRISTOYLTRANSFERASE; S (2 OXOPENTADECYL)COENZYME A; S (2,2 DIFLUORO 3 OXOHEXADECYL)COENZYME A; S (3,3 DIFLUORO 2 OXOPENTADECYL)COENZYME A; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; PRIORITY JOURNAL;

EID: 0028075434     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)89601-0     Document Type: Article

References (80)

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4. Synthesis and Biochemical Applications of Fluorine-Containing Peptides and Proteins
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7. The Reversible Hydration of Carbonyl Compounds in Aqueous Solution. Part I, The Keto/Gem-diol Equilibrium
8. An assay for myristoyl-CoA: protein N-myristoyltransferase activity based on ion-exchange exclusion of [3H]myristoyl peptide.