Influence of Nω-nitro-L-arginine methyl ester, LY83583, glybenclamide and L158809 on pulmonary circulation

European Journal of Pharmacology

Volumn 263, Issue 1-2, 1994, Pages 133-140

  Feng, Chang J ^a   Cheng, David Y ^a   Kaye, Alan D ^a   Kadowitz, Philip J ^a   Nossaman, Bobby D ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin AT1 receptor antagonist; ATP sensitive; Glybenclamide; Guanylate cyclase; Hypoxia; Hypoxic pulmonary vasoconstriction; K+ channel; L158809; LY83583; N Nitro L arginine methyl ester; Nitric oxide (NO) synthesis; Pulmonary circulation; Pulmonary vascular bed; rat; soluble

Indexed keywords

2 ETHYL 5,7 DIMETHYL 3 [4 [2 (2H TETRAZOL 5 YL)PHENYL]BENZYL]IMIDAZO[4,5 B]PYRIDINE; 6 ANILINO 5,8 QUINOLINEQUINONE; ACETYLCHOLINE; ANGIOTENSIN; ATROPINE; GLIBENCLAMIDE; GLYCERYL TRINITRATE; GUANYLATE CYCLASE INHIBITOR; LEMAKALIM; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; POTASSIUM CHANNEL BLOCKING AGENT; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENTIATION; HEART LEFT ATRIUM PRESSURE; HYPOXIA; LUNG ARTERY PRESSURE; LUNG CIRCULATION; LUNG PERFUSION; LUNG VASOCONSTRICTION; LUNG VENTILATION; MALE; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION; VASODILATATION;

AMINOQUINOLINES; ANIMAL; ANOXIA; ARGININE; DRUG INTERACTIONS; GLYBURIDE; IMIDAZOLES; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PULMONARY CIRCULATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANGIOTENSIN; TETRAZOLES; VASOCONSTRICTION;

EID: 0028067723     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(94)90533-9     Document Type: Article

References (16)

1. Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium-derived relaxing factor
2. ω-nitro-L-arginine selectively inhibits vasodilator responses to acetylcholine and bradykinin in cats
3. Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation
4. ω-nitro-L-arginine and alkyl esters of L-NA on pulmonary vasodilator responses to acetylcholine, bradykinin, and substance P
5. Relationship of the pulmonary vascular endothelium to altered pulmonary vascular resistance
6. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
7. Role of endothelium in responses of vascular smooth muscle to drugs
8. Effects of inhibitors of EDRF and EDHF on vasoreactivity of perfused rat lungs
9. Biosynthesis and metabolism of endothelium-derived nitric oxide
10. Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats
11. ω-Nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin
12. L-Arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation
13. Role of endothelium-derived nitric oxide in the regulation of blood pressure
14. Inhibition of nitric oxide synthesis potentiates hypoxic vasoconstriction in isolated rat lungs
15. Mechanism of hypoxic pulmonary vasoconstriction
16. Observations on the Pulmonary Arterial Blood Pressure in the Cat