Growth factors in wound healing

Clinics in Dermatology

Volumn 12, Issue 1, 1994, Pages 157-169

  Lawrence, W Thomas ^a,b   Diegelmann, Robert F ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR RECEPTOR; HUMAN GROWTH HORMONE; INTERFERON; INTERLEUKIN 1; KERATINOCYTE GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

ANGIOGENESIS; CHEMOTAXIS; COLLAGEN SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; MITOGENESIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; REVIEW; SCAR FORMATION; WOUND CONTRACTION; WOUND HEALING;

ANIMAL; GROWTH SUBSTANCES; HUMAN; MODELS, BIOLOGICAL; SKIN; WOUND HEALING;

EID: 0028052937     PISSN: 0738081X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0738-081X(94)90266-6     Document Type: Article

References (154)

1. Growth factors and wound repair
2. Syndecan, a developmentally regulated cell surface proteoglycan that binds extracellular matrix and growth factors
3. Response to growth factors of human dermal fibroblasts in a quiescent state owing to cell-matrix contact inhibition
4. What happened to urogastrone?
5. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal.
6. Epidermal growth factor
7. Human plasma epidermal growth factor/urogastrone is associated with blood platelets
8. Immunochemical localization of human epidermal growth factor/urogastrone in several human tissues
9. Epidermal growth factor
10. Characterization of Material With Epidermal Growth Factor Immunoreactivity in Human Serum and Platelets*
11. Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages
12. A rapid decrease in epidermal growth factor binding capacity accompanies the terminal differentiation of mouse myoblasts in vitro
13. Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cell
14. EGF and TGF-alpha are potent chemoattractants for endothelial cells and EGF-like peptides are present at sites of tissue regeneration
15. Stimulation of fibroblast migration by epidermal growth factor
16. New functions of epidermal growth factor: Stimulation of capillary endothelial cell migration and matrix dependent proliferation
17. Biological effects of biosynthetic human EGF on the growth of mammalian cells in vitro
18. Transforming growth factor alpha: A more potent angiogenic mediator than epidermal growth factor
19. Induction of collagenase secretion in human fibroblast cultures by growth promoting factors
20. Fibroblast growth factor: Structural and biological properties
21. Localization of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth
22. Endothelial cell-derived basic fibroblast growth factor: Synthesis and deposition into subendothelial extracellular matrix
23. Heparin affinity: Purification of a tumor-derived capillary endothelial cell growth factor
24. Recombinant basic fibroblast growth factor accelerates wound repair
25. Basic fibroblast growth factor accelerates tissue repair in models of impaired healing
26. Stimulation of growth of keratinocytes by basic fibroblast growth factor
27. Basic fibroblast growth factor stimulation of epidermal wound healing in pigs
28. Recombinant basic fibroblast growth factor accelerates wound healing
29. Platelets as a source of fibroblast growth-promoting activity
30. The platelet-derived growth factor
31. Studies of the release from human platelets of the growth factor for cultured human arterial smooth muscle cells
32. Human platelet-derived growth factor (PDGF): Purification of PDGF-I and PDGF-II and separation of their reduced subunits
33. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines
34. Platelet-derived growth factor: Identification of constituent poly-peptide chains
35. A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain
36. Binding of different dimeric forms of PDGF to human fibroblasts: Evidence for two separate receptor types
37. Activated human monocytes express the c-sis protooncogene and release a mediator showing PDGF-like activity
38. A significant part of macrophage-derived growth factor consists of at least two forms of PDGF
39. Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury
40. Platelet-derived growth factor and transforming growth factor-β enhance tissue repair activities by unique mechanisms
41. Chemotaxis of monocytes and neutrophils to platelet-derived growth factor
42. Platelet-derived growth factor in chemotactic for fibroblasts
43. Molecular mediators of tissue repair
44. Platelet-derived growth factor is a chemoattractant for vascular smooth muscle cells
45. Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate
46. Platelet-derived growth factor stimulates mouse 3T3 cell mitogenesis and leukocyte chemotaxis through structural determinants
47. Platelet-derived growth factor
48. Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells
49. Effect of growth factors on hyaluronan synthesis in cultured human fibroblasts
50. Stimulation of human in vitro human skin collagenase expression by platelet-derived growth factor
51. Platelet-derived growth factor: Structure, function, and roles in normal and transformed cells
52. Polypeptide growth factors: Roles in normal and abnormal cell growth
53. Dual control of cell growth by somatomedins and platelet-derived growth factor
54. Regulation of the BALB/C-3T3 cell cycle—Effects of growth factors
55. Mitogenic response to epidermal growth factor (EGF) modulated by platelet-derived growth factor
56. New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.
57. Multiple type-? transforming growth factors and their receptors
58. The TGF-β family of growth and differentiation factors
59. Tranforming growth factor-β in human platelets
60. Production of transforming growth factor-beta by human T lymphocytes and its potential role in the regulation of T cell growth
61. Expression and secretion of type β transforming growth factor by activated human macrophages
62. Some recent advances in the chemistry and biology of transforming growth factor-β
63. Transforming growth factors and the regulation of cell proliferation
64. Type beta transforming growth factor in human platelets: Release during degranulation and action on vascular smooth muscle cells
65. Transforming growth factor-beta (TGF-β) as an immunoregulatory molecule
66. Transforming growth factor type β induces monocyte chemotaxis and growth factor production
67. Transforming growth factor-beta (TGFβ) is chemotactic for human monocytes and induces their expression of angiogenic activity
68. Stimulation of chemotactic migration of fibroblasts by transforming growth factor-β
69. Type β transforming growth factor: A bifunctional regulator of cellular growth
70. Cellular transformation by coordinated action of three peptide growth factors from human platelets
71. Transforming growth factor-β: Biological function and chemical structure
72. Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro
73. Transforming growth factor-β regulation of collagenase, 72 kda-progelatinase, TIMP and PAI-1 expression in rat bone cell populations and human fibroblasts
74. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor
75. Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-β
76. Transforming growth factor β regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans
77. Transforming growth factor-β stimulates the expression of fibronectin by human keratinocytes
78. Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: Implications for wound healing
79. Fibroblasts from wounds of different stages of repair vary in their ability to contract a collagen gel in response to growth factors
80. Spatial organization of extracellular matrix and fibroblast activity: Effects of serum, TGF-β and fibronectin
81. Angiogenic factors
82. Growth modulation of mouse keratinocytes by transforming growth factors
83. Epidermal growth factor-like transforming growth factor II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells
84. Synthesis of messenger RNAs for transforming growth factors alpha and β and the epidermal growth factor receptor by human tumors
85. Induction of transforming growth factor alpha in activated human alveolar macrophages
86. Production and auto-induction of transforming growth factor alpha in human keratinocytes
87. Transforming growth factor alpha
88. Wound macrophages express TGF-alpha and other growth factors in vivo: Analysis by mRNA phenotyping
89. Functional and structural characteristics of EGF and its receptor and their relationship to transforming proteins
90. Potentiation of the T-lymphocyte response to lymphocytes. II. The cellular source of potentiating mediator(s)
91. Human leukocyte pyrogen: Purification and development of a radioimmunoassay
92. Prostaglandins as endogenous mediators of interleukin 1 production
93. Identification and characterization of chemoattractants for epidermal cells
94. Interleukin 1, potential regulator of fibroblast proliferation
95. Macrophage-derived growth factor for fibroblasts and interleukin-1 are distinct entities
96. 2 and indomethacin
97. Interleukin 1 stimulation of collagenase production by cultured fibroblasts
98. Cytokine regulation of human lung fibroblast hyaluronan production
99. Human endothelial cell cultures: Phenotypic modulation by leukocyte interleukins
100. Extension of the life-span of human endothelial cells by an interleukin-1 alpha antisense oligomer
101. Cachectin and tumor necrosis factor as two sides of the same biologic coin
102. Tumor necrosis factor: Receptor binding and mitogenic action in fibroblasts
103. 2 production by human synovial cells and dermal fibroblasts
104. Macro-phage-induced angiogenesis is mediated by tumor necrosis factor alpha
105. Tumor necrosis factor
106. Effects of topical applications of epidermal growth factor on wound healing
107. Enhancement of epidermal regeneration by biosynthetic epidermal growth factor
108. Stimulation of wound healing by epidermal growth factor
109. Sustained release of epidermal growth factor accelerates wound repair
110. Epidermal growth factor increases granulation tissue formation dose dependently
111. Epidermal growth factor increases tensile strength in intestinal wounds in pigs
112. EGF increases short-term type I collagen accumulation during wound healing in diabetic rats
113. Epidermal growth factor (EGF) prevents methylprednisolone-induced inhibition of wound healing
114. Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model
115. Preclinical wound-healing studies with recombinant human basic fibroblast growth factor
116. Effects of fibroblasts and basic fibroblast growth factor on facilitation of dermal wound healing by type I collagen matrices
117. Recombinant basic fibroblast growth factor accelerates wound healing
118. Fibroblast growth factor reverses the bacterial retardation of wound contraction
119. Effect of bFGF on the inhibition of contraction caused by bacteria
120. Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice
121. PDGF and FGF stimulate wound healing in the genetically diabetic mouse
122. Effects of homodimeric isoforms of platelet-derived growth factor (PDGF-AA and PDGF-BB) on wound healing in rat
123. Effects of growth factors in vivo
124. Role of platelet-derived growth factor in wound healing
125. In vivo incisional wound healing augmented by platelet-derived growth factor and recombinant c-sis gene homodimeric proteins
126. Platelet-derived growth factor and transforming growth factor-β enhance tissue repair activities by unique mechanisms
127. Reversal of impaired wound healing in irradiated rats by platelet-derived growth factor-BB
128. PDGF and FGF stimulate wound healing in the genetically diabetic mouse
129. Platelet-derived growth factor (BB homodimer), transforming growth factor-β1, and basic fibroblast growth factor in dermal wound healing
130. Transforming growth factor type β: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro
131. Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo
132. Exogenous transforming growth factor-beta 2 enhances connective tissue formation and wound strength in guinea pig dermal wounds healing by secondary intent
133. Accelerated healing of incisional wounds in rats induced by transforming growth factor β
134. The reversal of an Adriamycin induced healing impairment with chemoattractants and growth factors
135. Reversal of Adriamycin-impaired wound healing by transforming growth factor-beta
136. Transforming growth factor-β improves healing of radiation-impaired wounds
137. Transforming growth factor β reverses the glucocorticoid-induced wound-healing deficit in rats: Possible regulation in macrophages by platelet-derived growth factor
138. Tumor necrosis factor-δ inhibits in vivo collagen synthesis
139. Tumor necrosis factor and wound healing
140. Epithelial wound healing enhanced by transforming growth factor-alpha and vaccinia growth factor
141. Interleukin 2 enhances wound healing in rats
142. The effect of interleukin-2 administration on wound healing in Adriamycin-treated rats
143. Classification treatment of chronic nonhealing wounds
144. Stimlation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula
145. Use of homologous platelet factors in achieving total healing of recalcitrant skin ulcers
146. Randomized prospective double-blind trial in healing chronic diabetic foot ulcers
147. A prospective randomized trial of autologous platelet-derived wound healing factors for treatment of chronic nonhealing wounds: A preliminary report
148. Recombinant human platelet-derived growth factor-BB for the treatment of chronic pressure ulcers
149. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers
150. Enhancement of wound healing by topical treatment with epidermal growth factor
151. Stimulation of healing of chronic wounds by epidermal growth factor
152. Topical use of human recombinant epidermal growth factor (h-EGF) in venous ulcers
153. The safety and effect of topically applied recombinant basic fibro-blast growth factor on the healing of chronic pressure sores
154. Degradation of fibronectin and vitronectin in chronic wound fluid: Analysis by cell blotting, immunoblotting, and cell adhesion assays