Parenteral glutamine dipeptide supplementation does not ameliorate chemotherapy‐induced toxicity

Cancer

Volumn 74, Issue 10, 1994, Pages 2879-2884

  van Zaanen, Henk C T ^a   van der Lelie, Hans ^a   Timmer, John G ^a   Fürst, Peter ^b   Sauerwein, Hans P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

glutamine; hematology; total parenteral nutrition; toxicity

Indexed keywords

ALANYLGLUTAMINE; AMINO ACID MIXTURE; AMSACRINE; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; CYTARABINE; VINCRISTINE;

ADULT; AGED; AMINO ACID COMPOSITION; ARTICLE; BURKITT LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; LEUKEMIA; LEUKOCYTE COUNT; MALE; MORTALITY; NEUTROPENIA; NEUTROPHIL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TOTAL PARENTERAL NUTRITION;

ADULT; AGED; ANTINEOPLASTIC AGENTS; DIPEPTIDES; DOUBLE-BLIND METHOD; FEMALE; FOOD, FORTIFIED; GLUTAMINE; HEMATOLOGIC DISEASES; HUMANS; MALE; MIDDLE AGED; PARENTERAL NUTRITION, TOTAL; PILOT PROJECTS; PROSPECTIVE STUDIES;

EID: 0028046940     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(19941115)74:10<2879::AID-CNCR2820741022>3.0.CO;2-H     Document Type: Article

References (27)

1. Intracellular muscle free amino‐acids; their measurement and function
2. Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats: quantitative importance of glutamine, glutamate and aspartate
3. A role for muscle in the immune system and its importance in surgery, trauma, sepsis and burns
4. The potential use of dipeptide in clinical nutrition
5. Availability of amino acids supplied intravenously in healthy man as synthetic dipeptides: kinetic evaluation of L‐alanyl‐L‐glutamine and glycyl‐L‐tyrosine
6. Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery
7. Addition of glutamine to TPN after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis and improves nitrogen balance
8. Alanyl‐glutamine counteracts the depletion of free glutamine and the postoperative decline in protein synthesis in skeletal muscle
9. The effect of alanyl‐glutamine peptide supplementation on muscle protein synthesis in post‐surgical patients receiving glu tamine‐free amino acids intravenously
10. Potential role of glutamine supplementation in nutrition support
11. Glutamine and the preservation of gut integrity
12. Total parenteral nutrition promotes bacterial translocation from the gut
13. Glutamine: an essential nonessential amino acid for the gut
14. The influence of parenteral glutamine and branched‐chain amino acids on TPN‐induced atrophy of the gut
15. Alanyl‐glutamine enriched TPN restores intestinal adaptation after either proximal or distal massive resection in rats
16. Effect of glutamine on protein synthesis in isolated intestinal epithlial cells
17. The effect of glutamine‐enriched TPN on gut immune cellularity
18. Effect of glutamine‐supplemented total parenteral nutrition on recovery of the small intestine after starvation atrophy
19. Clinical and metabolic efficacy of glutamine supplemented parenteral nutrition after bone marrow transplantation
20. Total parenteral nutrition with glutamine in bone marrow transplantation and other clinical applications
21. Incidence and clinical epidemiology of Streptococcal septicemia during treatment of acute my eloid leukemia
22. Staphylococcus epidermidis: an increasing cause of infection in patients with granulocytopenia
23. Infection in cancer patients
24. The value of surveillance cultures in neutropenic patients receiving selective intestinal decontamination
25. Alanyl‐glutamine infusions to patients with acute pancreatitis
26. The intensive care patient