메뉴 건너뛰기




Volumn 180, Issue 6, 1994, Pages 2173-2179

Protective effect of 55- but not 75-kD soluble tumor necrosis factor receptor-immunoglobulin G fusion proteins in an animal model of gram-negative sepsis

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY TN3; RECEPTOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0028043394     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.180.6.2173     Document Type: Article
Times cited : (157)

References (36)
  • 1
    • 0025894865 scopus 로고
    • Pathophysiology and treatment of septic shock
    • Rackow, E.C., and M.E. Astiz. 1991. Pathophysiology and treatment of septic shock. J. Am. Med. /Issue. 266:548.
    • (1991) J. Am. Med , vol.266 , pp. 548
    • Rackow, E.C.1    Astiz, M.E.2
  • 5
    • 0027528798 scopus 로고
    • An ticytokine strategies in the treatment of the systemic inflam matory response syndrome
    • Dinarello, C.A., J.A. Gelfand, and S.M. Wolff. 1993. An ticytokine strategies in the treatment of the systemic inflam matory response syndrome. J. Am. Med. /Issue. 269:1829.
    • (1993) J. Am. Med , vol.269 , pp. 1829
    • Dinarello, C.A.1    Gelfand, J.A.2    Wolff, S.M.3
  • 11
    • 0025098536 scopus 로고
    • Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor
    • Espevik, T., M. Brockhaus, H. Loetscher, U. Nonstad, and R. Shalaby. 1990. Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor. J. Exp. Med. 171:415.
    • (1990) J. Exp. Med. , vol.171 , pp. 415
    • Espevik, T.1    Brockhaus, M.2    Loetscher, H.3    Nonstad, U.4    Shalaby, R.5
  • 16
    • 0024357657 scopus 로고
    • The structure of tumor necrosis factor alpha at 2.6 A resolution: Implications for receptor binding
    • Eck, M.J., and S.R. Sprang. 1989. The structure of tumor necrosis factor alpha at 2.6 A resolution: implications for receptor binding. J. Biol. Chem. 264:17595.
    • (1989) J. Biol. Chem. , vol.264 , pp. 17595
    • Eck, M.J.1    Sprang, S.R.2
  • 19
    • 0025165135 scopus 로고
    • Two tumor- necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors
    • Engelmann, H., D. Novick, and D. Wallach. 1990. Two tumor- necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. J. Biol. Chem. 265:1531.
    • (1990) J. Biol. Chem. , vol.265 , pp. 1531
    • Engelmann, H.1    Novick, D.2    Wallach, D.3
  • 20
    • 0025113598 scopus 로고
    • Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino-acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor
    • Nophar, Y., O. Kemper, C. Brakebusch, H. Engelmann, R. Zwang, D. Aderka, H. Holtmann, and D. Wallach. 1990. Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino-acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. EMBO (Eur. Mol. Biol. Organ.) J. 9:3269.
    • (1990) EMBO (Eur. Mol. Biol. Organ.) J. , vol.9 , pp. 3269
    • Nophar, Y.1    Kemper, O.2    Brakebusch, C.3    Engelmann, H.4    Zwang, R.5    Aderka, D.6    Holtmann, H.7    Wallach, D.8
  • 21
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective ther apeutic agents in lethal endotoxemia and function simultane ously as both TNF carriers and TNF antagonists
    • Mohler, K.M., D.S. Torrance, C. Smith, R.G. Goodwin, K.E. Stremler, V.P. Fung, H. Madani, and M.B. Widmer. 1993. Soluble tumor necrosis factor (TNF) receptors are effective ther apeutic agents in lethal endotoxemia and function simultane ously as both TNF carriers and TNF antagonists. J. Immunol. 151:1548.
    • (1993) J. Immunol. , vol.151 , pp. 1548
    • Mohler, K.M.1    Torrance, D.S.2    Smith, C.3    Goodwin, R.G.4    Stremler, K.E.5    Fung, V.P.6    Madani, H.7    Widmer, M.B.8
  • 23
    • 0025333163 scopus 로고
    • Prophylactic and therapeutic effects of a monoclonal antibody to tumour necrosis factor-alpha in experimental Gram-negative shock
    • Silva, A.T., K.F. Bayston, and J. Cohen. 1990. Prophylactic and therapeutic effects of a monoclonal antibody to tumour necrosis factor-alpha in experimental Gram-negative shock. J. Biol. 162:421.
    • (1990) J. Biol. , vol.162 , pp. 421
    • Silva, A.T.1    Bayston, K.F.2    Cohen, J.3
  • 24
    • 0027215479 scopus 로고
    • Superantigens associated with Staphylococcal and Streptococcal toxic shock syndrome are potent inducers of tumor necrosis factorβ Synthesis
    • Hackett, S.P., and D.L. Stevens. 1993. Superantigens associated with Staphylococcal and Streptococcal toxic shock syndrome are potent inducers of tumor necrosis factorβ synthesis.J. In fect. Dis. 168:232.
    • (1993) J. In Fect. Dis. , vol.168 , pp. 232
    • Hackett, S.P.1    Stevens, D.L.2
  • 27
    • 0026741275 scopus 로고
    • Tumor necrosis factor soluble receptors circulate during experimental and clinical inflamma tion and can protect against excessive tumor necrosis factor a in vitro and
    • Van Zee, K.J., T. Kohno, E. Fischer, C.S. Rock, L.L. Mol- dawer, and S. Lowry. 1992. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflamma tion and can protect against excessive tumor necrosis factor a in vitro and in vivo. Proc Natl. Acad. Sci. USA. 89:4845.
    • (1992) In Vivo. Proc Natl. Acad. Sci. USA , vol.89 , pp. 4845
    • Van Zee, K.J.1    Kohno, T.2    Fischer, E.3    Rock, C.S.4    Moldawer, L.L.5    Lowry, S.6
  • 30
    • 0025258906 scopus 로고
    • Requirement of endogenous tumor necrosis factor/ cachectin for recovery from experimental peritonitis
    • Echtenacher, B., W. Falk, D.N. Mannel, and P.H. Krammer. 1990. Requirement of endogenous tumor necrosis factor/ cachectin for recovery from experimental peritonitis. J. Immunol. 145:3762.
    • (1990) J. Immunol. , vol.145 , pp. 3762
    • Echtenacher, B.1    Falk, W.2    Mannel, D.N.3    Krammer, P.H.4
  • 31
    • 0021269574 scopus 로고
    • Comparison of in vitro cell cytotoxic assays for tumor necrosis factor
    • Flick, D.A., and G.E. Gifford. 1984. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor. J. Immunol. Methods. 68:167.
    • (1984) J. Immunol. Methods. , vol.68 , pp. 167
    • Flick, D.A.1    Gifford, G.E.2
  • 33
    • 0027263992 scopus 로고
    • Differences in cytokine response and induction of nitric oxide synthase in endotoxin-resistant and endotoxin-sensitive mice after intravenous Gram-negative infection
    • Evans, T.J., E. Strivens, A. Carpenter, and j. Cohen. 1993. Differences in cytokine response and induction of nitric oxide synthase in endotoxin-resistant and endotoxin-sensitive mice after intravenous Gram-negative infection. J. Immunol. 150:5033.
    • (1993) J. Immunol. , vol.150 , pp. 5033
    • Evans, T.J.1    Strivens, E.2    Carpenter, A.3    Cohen, J.4
  • 34
    • 0026688566 scopus 로고
    • Differen tial effects of monoclonal antibodies to tumor necrosis factor alpha and gamma interferon on induction of hepatic nitric oxide synthase in experimental Gram-negative sepsis
    • Evans, T., A. Carpenter, A. Silva, and J. Cohen. 1992. Differen tial effects of monoclonal antibodies to tumor necrosis factor alpha and gamma interferon on induction of hepatic nitric oxide synthase in experimental Gram-negative sepsis. Infect. Immun. 60:4133.
    • (1992) Infect. Immun. , vol.60 , pp. 4133
    • Evans, T.1    Carpenter, A.2    Silva, A.3    Cohen, J.4
  • 35
    • 0026516744 scopus 로고
    • Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
    • Aderka, D., H. Engelmann, Y. Maor, C. Brakebusch, and D. Wallach. 1992. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J. Exp Med. 175:323.
    • (1992) J. Exp Med. , vol.175 , pp. 323
    • Aderka, D.1    Engelmann, H.2    Maor, Y.3    Brakebusch, C.4    Wallach, D.5
  • 36
    • 0027301244 scopus 로고
    • Ligand passing: The 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signalling by the 55-kDa TNF receptor
    • Tartaglia, L.A., D. Pennica, and D.V. Goeddel. 1993. Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signalling by the 55-kDa TNF receptor. Proc. Natl. Acad. Sci. USA. 268:18542
    • (1993) Proc. Natl. Acad. Sci. USA. , vol.268 , pp. 18542
    • Tartaglia, L.A.1    Pennica, D.2    Goeddel, D.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.