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Volumn 33, Issue 17, 1994, Pages 1699-1720

Peptidomimetics—Tailored Enzyme Inhibitors

Author keywords

Inhibitors; Medicinal chemistry; Peptidomimetics

Indexed keywords


EID: 0028038601     PISSN: 05700833     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.199416991     Document Type: Review
Times cited : (892)

References (371)
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    • A peptidomimetic is defined as a substance having a secondary structure as well as other structural features analogous to that of the original peptide, which allows it to displace the original peptide from receptors or enzymes. As a result the effects of the original peptide are inhibited (antagonist, inhibitor) or duplicated (agonist).
  • 12
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    • Kontakte (Darmstadt), (2), 55
    • (1991)
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    • Die Medizinische Chemie im Goldenen Zeitalter der Biologie: Lehren aus der Steroid- und Peptidforschung
    • (1991) Angewandte Chemie , vol.103 , pp. 1305
    • Hirschmann, R.1
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    • (a) Review:, Synthesis
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    • Gante, J.1
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    • Peptidähnliche Systeme, VII. Über neue Möglichkeiten bei der Synthese von Azapeptiden
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    • Gante, J.1
  • 140
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    • Peptoide – Schlüsselverbindungen für einen neuen Weg zur Entwicklung von pharmazeutischen Wirkstoffen
    • (1993) Angewandte Chemie , vol.105 , pp. 572
    • Kessler, H.1
  • 147
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    • Collective term for enzymes that catalyze the hydrolytic cleavage of the peptide bond in proteins and peptides: Römpp Chemie‐Lexikon, Thieme, Stuttgart, p. 3647.
    • (1992)
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    • (Behringwerke AG), EP‐B 508220
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    • (a) Addendum: Many publications on the topics in this review have appeared since the submission of this manuscript. A selection (up to April 1994) are listed here. Structure:, J. Chem. Soc. Perkin Trans. 1
    • (1993) , pp. 2843
    • Quibell, M.1    Turnell, W.G.2    Johnson, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.