Effect of cytokines on the secretion of the fifth and eighth complement components by HepG2 cells

International Journal of Clinical & Laboratory Research

Volumn 24, Issue 1, 1994, Pages 45-48

  Perissutti, Sabrina ^a   Tedesco, Francesco ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Complement secretion; Cytokines; HepG2 cells

Indexed keywords

COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C8; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; TUMOR PROTEIN;

ARTICLE; CELL CULTURE; COMPARATIVE STUDY; DRUG EFFECT; HUMAN; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; PATHOLOGY; PHYSIOLOGY; SECRETION;

CARCINOMA, HEPATOCELLULAR; COMPARATIVE STUDY; COMPLEMENT 5; COMPLEMENT 8; HUMAN; INTERLEUKIN-1; INTERLEUKIN-6; LIVER; LIVER NEOPLASMS; NEOPLASM PROTEINS; SECRETORY RATE; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR;

EID: 0028038530     PISSN: 09405437     EISSN: 14344467     Source Type: Journal    
DOI: 10.1007/BF02592409     Document Type: Article

References (16)

1. Human C3: evidence for the liver as the primary site of synthesis
2. Studies of hepatic synthesis in vivo of plasma proteins including orosomucoid, transferrin, alpha-1-antitrypsin, C8 and factor B
3. Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells
4. Complement biosynthesis
5. Regulation of complement biosynthesis by tissue-specific and hormonal factors
6. Hormonal regulation of complement biosynthesis in human cell lines. II. Upregulation of the biosynthesis of complement components C3, factor B and C1 inhibitor by interleukin-6 and interleukin-1 in human hepatoma cell line
7. Complement technology
8. Chromosomal assignment of genes encoding the α, β, and τ subunits of human complement protein C8: identification of a close physical linkage between the α and the β loci
9. Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects
10. Complement biosynthesis by the human hepatoma-derived cell line HepG2
11. Aspects of the acute phase response: the C-reactive protein system
12. Complement: molecular genetics
13. Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression
14. Biosynthesis of the third (C3), eighth (C8), and ninth (C9) complement components by guinea pig hepatocyte primary cultures
15. Meyer zum Büschenfelde K-H, Interleukin 6, the third mediator of acutephase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1β and tumor necrosis factor-α
16. Two distinct abnormalities in patients with C8α-τ deficiency. Low level of C8β chain and presence of dysfunctional C8α-τ subunit