Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: A putative probe of CYP2E1 activity

Clinical Pharmacology & Therapeutics

Volumn 56, Issue 4, 1994, Pages 359-367

  O'Shea, Diamuird ^a   Davis, Stephen N ^a   Kim, Richard B ^a   Wilkinson, Grant R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 HYDROXYCHLORZOXAZONE; CHLORZOXAZONE; CYTOCHROME P450 ISOENZYME; DRUG METABOLITE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET RESTRICTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HYDROXYLATION; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OBESITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; URINARY EXCRETION;

ADULT; BODY MASS INDEX; CHLORZOXAZONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FASTING; FEMALE; HUMANS; HYDROXYLATION; MALE; OBESITY; OXIDOREDUCTASES, N-DEMETHYLATING;

EID: 0028037221     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.1994.150     Document Type: Article

References (0)