The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

Cell

Volumn 79, Issue 3, 1994, Pages 507-513

  Chong, Lisa D ^a   Traynor Kaplan, Alexis ^b   Bokoch, Gary M ^a   Schwartz, Martin Alexander ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA; ANIMALIA;

ACTIN; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; MEVINOLIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PLATELET DERIVED GROWTH FACTOR; RHO FACTOR; THROMBIN;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS;

EID: 0028036684     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(94)90259-3     Document Type: Article

References (36)

1. rho proteins
2. Botulinum ADP-ribosyl transferase a new tool to study low molecular weight GTP-binding proteins
3. A chimeric toxin to study the role of the 21 kDa GTP binding protein Rho in the control of actin microfilament assembly
4. Characterization and expression of the human rhoH12 gene product
5. The human erythrocyte contains two forms of phosphatidylinositol 4-phosphate 5-kinase which are differentially active towards membranes
6. Mevalonate controls cytoskeleton organization and cell morphology in thyroid epithelial cells
7. Isoprenoid metabolism is required for stimulation of the respiratory burst of HL60 cells
8. Phosphoinositide kinases
9. Determination of mass changes in phosphatidylinositol 45-bisphosphate and evidence for agonist-stimulated metabolism of inositol 145-triphosphate in airway smooth muscle
10. Regulation of intracellular actin polymerization by prenylated cellular proteins
11. Requirement of phosphatidylinositol 45-bisphosphate for α-actinin function
12. Identification of distinct cytoplasmic target for ras/R-ras and rho regulatory proteins
13. Complexes of polyoma virus medium T antigen and cellular proteins
14. Ras related proteins
15. Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase
16. Inositol lipids dissociate gelsolin-actin complexes
17. − secretion in T84 cells
18. Carboxylterminal isoprenylation of ras-related GTP-binding proteins encoded by rac1 rac2 and ralA
19. Purification and characterization of Rac2 a cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase
20. Specific interaction between phosphatidylinositol-45-bisphosphate and profilactin
21. Characterization and purification of membrane-associated phosphatidyl inositol-4-phosphate kinase from human red blood cell
22. Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown
23. Role of phosphoinositides in transmembrane signaling
24. The small GTP binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
25. The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
26. Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium
27. Adhesion is required for protein kinase C-dependent activation of the Na-H antiporter by platelet-derived growth factor
28. A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelail cells
29. Different structural organization of Ras and Rho effector domains
30. A novel phosophoinositide kinase activity in myeloid derived cells is activated by G protein βγ subunits
31. 2+-ATPase
32. Transient increase in phosphatidylinositol 34-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils
33. Cell shape and increased free cytosolic calcium induced by growth factors
34. Stimulation of phosphatidylinositol 4-phosphate phosphorylation in human placenta membranes by GTPγS
35. Cap39 a calcium ion- and polyphosphoinositide-regulated actin capping protein
36. Activation of platelet phosphatidylinositol 3-kinase requires the small GTP-binding protein Rho