Characterization of the tyrosyl radicals in ovine prostaglandin H synthase-1 by isotope replacement and site-directed mutagenesis

Journal of Biological Chemistry

Volumn 269, Issue 7, 1994, Pages 5085-5091

  Tsai, Ah Lim ^a   Hsi, Linda C ^b   Kulmacz, Richard J ^a   Palmer, Graham ^c   Smith, William L ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; FREE RADICAL; HYDROPEROXIDE; INDOMETACIN; PEROXIDASE; PHENYLALANINE; PROSTAGLANDIN SYNTHASE; TYROSINE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ANALYSIS; ISOTOPE LABELING; MICROSOME; NONHUMAN; PRIORITY JOURNAL; SHEEP; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; GENE EXPRESSION; HYDROGEN PEROXIDE; INDOMETHACIN; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECOMBINANT PROTEINS; SHEEP; SUBSTRATE SPECIFICITY; TRANSFECTION; TYROSINE;

ANIMALIA; OVIS; OVIS ARIES;

EID: 0028033328     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Samuelsson, B., Goldyne, M., Granström, E., Hamberg, M., Hammarström, S., and Malmsten, C. (1978) Annu. Rev. Biochem. 47, 997-1029
2. Miyamoto, T., Ogino, N., Yamamoto, S., and Hayaishi, O. (1976) J. BioL Chem. 251, 2629-2636
3. Hemler, M. E., Graff, G., and Lands, W. E. M. (1978) Biochem. Biophys. Res. Commun. 85, 1325-1331
4. Smith, W. L., and Lands, W. E. M. (1972) Biochemistry 11, 3276-3285
5. Kulmacz, R. J., Tsai, A.-L., and Palmer, G. (1987) J. Biol. Chem. 262, 10524-10531
6. Karthein, R., Dietz, R., Nastainczyk, W., and Ruf, H. H. (1988) Eur. J. Biochem. 171, 313-320
7. Kulmacz, R. J., Ren, Y., Tsai, A.-L., and Palmer, G. (1990) Biochemistry 29, 8760-8770
8. Tsai, A.-L., Palmer, G., and Kulmacz, R. J. (1992) J. Biol. Chem. 287, 17753-17759
9. Barry, B. A., El-Deeb, M. K., Sandusky, P. O., and Babcock, G. T. (1990) J. Biol. Chem. 265, 20139-20143
10. DeGray, J. A., Lassmann, G., Curtis, J. F., Kennedy, T. A., Marnett, L. J., Eling, T.E., and Mason, R. P. (1992) J. Biol. Chem. 267, 23583-23588
11. Kulmacz, R. J., Palmer, G., and Tsai, A.-L. (1991) Mol. Pharmacol. 40, 833-837
12. Lassmann, G., Odenwaller, R., Curtis, J. F., DeGray, J. A., Mason, R. P., Marnett, L. J., and Eling, T. E. (1991) J. Biol. Chem. 266, 20045-20055
13. Smith, W. L., DeWitt, D. L., Kraemer, S. A., Andrews, M. J., Hla, T., Maciag, T., and Shimokawa, T. (1990) Adv. Prostaglandin Thromboxane Leukotriene Res. 20, 14-21
14. Shimokawa, T., Kulmacz, R. J., DeWitt, D. L., and Smith, W. L. (1990) J. Biol. Chem. 265, 20073-20076
15. Graff, G. (1982) Methods Enzymol. 86, 386-392
16. Bird, P., Gething, M.-J., and Sambrook, J. (1987) J. Cell. Biol. 105, 2905-2913
17. DeWitt, D. L., El-Harith, E. A., Kraemer, S. A., Andrews, M. J., Yao, E. F., Armstrong, R. L., and Smith, W. L. (1990) J. Biol. Chem. 265, 5192-5198
18. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
19. DeWitt, D. A., and Smith, W. L. (1988) Proc. Natl. Acad. Sci. U. S. A. 86, 1412-1416
20. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
21. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., pp. 21-52, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
22. Drezen, G., Bellard, M., Sassone-Corsi, P., and Chambon, P. (1981) Anal. Biochem. 112, 295-298
23. Shimokawa, T., and Smith, W. L. (1991) J. Biol. Chem. 266, 6168-6173
24. Shimokawa, T., Kulmacz, R. J., DeWitt, D. L., and Smith, W. L. (1990) J. Biol. Chem. 265, 20073-20076
25. Ruan, K.-H., Kulmacz, R. J., Wilson, A., and Wu, K. K. (1993) J. Immunol. Methods 162, 23-30
26. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
27. Lambeir, A. M., Markey, C. M., Dunford, H. B., and Marnett, L. J. (1985) J. Biol. Chem. 260, 14894-14896
28. Sjöberg, B.-M., Reichard, P., Graslund, A., and Ehrenberg, A. (1977) J. Biol. Chem. 252, 536-541
29. Wagner, A. F. V., Frey, M., Neugebauer, F. A., Schafer, W., and Knappe, J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 996-1000
30. Wilks, A., and Ortiz de Montellano, P. R. (1992) J. Biol. Chem. 267, 8827-8833
31. Hori, H., and Yonetani, T. (1985) J. Biol. Chem. 260, 349-355
32. Sivaraja, M., Goodin, D. B., Smith, M., and Hoffman, B. M. (1989) Science 245, 738-740
33. Prince, R. (1988) Trends Biochem. Sci. 13, 286-288
34. Hsi, L. C., Tsai, A.-L., Kulmacz, R. J., English, D. G., Siefker, A. O., Otto, J. C., and Smith, W. L. (1993) J. Lipid Mediators 6, 131-138
35. Mauro, J., Fishel, L. A., Hazzard, J. T., Meyer, T. E., Tollin, G., Cusanovich, M. A., and Kraue, J. (1988) Biochemistry 27, 6243-6256
36. Nelson, M. J., Cowling, R. A., Seitz, S. P., Buck, C., and Scarrow, R. C. (1993) FASEB J. 7, A1059