Activation of human dendritic cells through CD40 Cross-linking

Journal of Experimental Medicine

Volumn 180, Issue 4, 1994, Pages 1263-1272

  Caux, Christophe ^a   Massacrier, Catherine ^a   Vanbervliet, Béatrice ^a   Dubois, Bertrand ^a   Kooten, Cees Van ^a   Durand, Isabelle ^a   Banchereau, Jacques ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ANTIGEN; CYTOKINE;

ANTIGEN DETECTION; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL INTERACTION; CELL STIMULATION; CONTROLLED STUDY; CROSS LINKING; DENDRITIC CELL; HUMAN; HUMAN CELL; LANGERHANS CELL; PRIORITY JOURNAL;

ADULT; ANTIGENS, CD; ANTIGENS, CD40; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; CYTOKINES; DENDRITIC CELLS; HUMAN; RECEPTORS, INTERLEUKIN-2; UP-REGULATION;

EID: 0028033310     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.180.4.1263     Document Type: Article

References (50)

1. Banchereau, J., F. Bazan, D. Blanchard, F. Brfere, J.-P. Galizzi, C. van Kooten, Y.-J. Liu, F. Rousset, and S. Saeland. 1994. The CD40 and its Ligand. Anttu. Ren Immunol 52:881.
2. Paulie, S., B. Ehlin-Henriksson, H. Mellstedt, H. Koho, H. Ben-Aissa, and P. Perlmann. 1985. A p50 surface antigen restricted to human urinary bladder carcinomas and B lymphocytes. Cancer Immunol Immunother. 20:23.
3. Clark, E.A., and J.A. Ledbetter. 1986. Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. Proc Natl Acad. Sci. USA. 83:4494.
4. Stamenkovic, I., E.A. Clark, and B. Seed. 1989. A B-lympho-cyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO (Eur. Mol Biol. Organ.) J. 8:1403.
5. Banchereau, J., P. de Paoli, A. Valfe, E. Garcia, and F. Rousset. 1991. Long term human B cell lines dependent on interleukin 4 and anti-CD40. Science (Wash. DC). 251:70.
6. Rousset, F., E. Garcia, and J. Banchereau. 1991. Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J. Exp. Med. 173:705.
7. Jabara, H.H., S.M. Fu, R.S. Geha, and D. Vercelli. 1990. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J. Exp Med. 172:1861.
8. + ) B cells to secrete IgGl and IgG3. J. Exp Med. 179:757.
9. Armitage, R.J., W.C. Fanslow, L. Strockbine, T.A. Sato, K.N. Clifford, B.M. Macduff, D.M. Anderson, S.D. Gimpel, T. Davis-Smith, C.R. Maliszewski, et al. 1992. Molecular and biological characterization of a murine ligand for CD40. Nature (Lonl). 357:80.
10. Noelle, R.J., J.A. Ledbetter, and A. Aruffo. 1992. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunol. Today. 13:431.
11. Spriggs, M.K., W.C. Fanslow, R.J. Armitage, and J. Belmont. 1993. The biology of the human ligand for CD40. J. Clin. Immunol. 13:373.
12. Foy, T.M., D.M. Shepherd, F.H. Durie, A. Aruffo, J.A. Ledbetter, and R.J. Noelle. 1993. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. J. Exp Med. 178:1567.
13. Aruffo, A., M. Farrington, D. Hollenbaugh, X. Li, A. Milatovich, S. Nonoyama, J. Bajorath, L.S. Grosmaire, R. Stenkamp, M. Neubauer, et al. 1993. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell. 72:291.
14. Allen, R.C., R.J. Armitage, M.E. Conley, H. Rosenblatt, N.A. Jenkins, N.G. Copeland, M.A. Bedell, S. Edelhoff, C.M. Dis-teche, D.K. Simoneaux, et al. 1993. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science (Wash. DC). 259:990.
15. Korthluer, U., D. Graf, H.W. Mages, F. Brfere, M. Padayachee, S. Malcolm, A.G. Ugazio, L.D. Notarangelo, R.J. Levinsky, and R.A. Kroczek. 1993. Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature (Lond.). 361:539.
16. DiSanto, J.P., J.Y. Bonnefoy, J.F. Gauchat, A. Fischer, and G. de Saint Basile. 1993. CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM. Nature (Lond.). 361:541.
17. Fuleihan, R., N. Ramesh, R. Loh, H. Jabara, F.S. Rosen, T. Chatila, S.-M. Fu, I. Stamenkovic, and R.S. Geha. 1993. Defective expression of the CD40 ligand in X chromosome-linked immunoglubulin deficiency with normal or elevated IgM. Proc Natl Acad. Sci. USA. 90:2170.
18. Saeland, S., V. Duvert, I. Moreau, and J. Banchereau. 1993. Human B cell precursors proliferate and express CD23 after CD40 ligation. J. Exp Med. 178:113.
19. Galy, A.H.M., and H. Spits. 1992. CD40 is functionally expressed on human thymic epithelial cells. J Immunol 149:775.
20. Alderson, M.R., R.J. Armitage, TW. Tough, L. Strockbine, W.C. Fanslow, and M.K. Spriggs. 1993. CD40 expression by human monocytes: regulation of cytokines and activation of monocytes by the ligand for CD40. J. Exp Med. 178:669.
21. Steinman, R.M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol 9:271.
22. Romani, N., A. Lenz, H. Glassl, H. Stossel, U. Stanzl, O. Majdic, P. Fritsch, and G. Schuler. 1989. Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and function. J. Invest. Dermatol. 93:600.
23. Freudenthal, P.S., and R.M. Steinman. 1990. The distinct surface of human blood dendritic cells, as observed after an improved isolation method. Proc Natl Acad. Sci. USA. 87:7698.
24. Caux, C., C. Dezutter-Dambuyant, D. Schmitt, and J. Banchereau. 1992. GM-CSF and TNF-cr cooperate in the generation of dendritic Langerhans cells. Nature (Lond.). 360:258.
25. + hematopoietic progenitor cells. Blood. 75:2292.
26. Caux, C., C. Favre, S. Saeland, V. Duvert, I. Durand, P. Mannoni, and J. Banchereau. 1991. Potentiation of early hemato-poiesis by tumor necrosis factor-a is followed by inhibition of granulopoietic differentiation and proliferation. Blood. 78:635.
27. Vallé, A., C.E. Zuber, T. Defiance, O. Djossou, M. De Rie, and J. Banchereau. 1989. Activation of human B lymphocytes through CD40 and interleukin 4. Eur. J. Immunol. 19:1463.
28. van Kooten, C., C. Gaillard, J.-P. Galizzi, P. Hermann, F. Fos-siez, J. Banchereau, and D. Blanchard. 1994. B cells regulate expression of CD40-ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40. Eur. J. Immunol. 24:787.
29. Valfe, A., P. Garrone, H. Yssel, J.Y. Bonnefoy, A.S. Freedman, G. Freeman, L.M. Nadler, and J. Banchereau. 1990. Mab 104, a new monoclonal antibody, recognizes the B7 antigen which is expressed on activated B cells and HTLV-1 transformed T cells. Immunology. 69:531.
30. Nozawa, Y., E. Wachi, K. Tominaga, M. Abe, and H. Wakasa. 1993. A novel monoclonal antibody (FUN-1) identifies an activation antigen in cells of the B-cell lineage and Reed-Stemberg cells. J. Pathol 169:309.
31. Chretien, I., A. Van Kimmenade, M.K. Pearce, J. Banchereau, and J.S. Abrams. 1989. Development of polyclonal and monoclonal antibodies or immunoassay and neutralization of human interleukin-4. J. Immunol. Methods. 117:67.
32. Abrams, J.S., M.-G. Roncarolo, H. Yssel, U. Anders son, GJ. Gleich, and J.E. Silver. 1992. Strategies of anti-cytokine monoclonal antibody development: Immunoassay of IL-IO and IL-5 in clinical samples. Immunol. Rev. 127:5.
33. Burdin, B., C. Péronne, J. Banchereau, and F. Rousset. 1993. Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10. J. Exp. Med 177:295.
34. Van den Eertwegh, A.J.M., RJ. Noelle, M. Roy, D.M. Shepherd, A. Aruffo, J.A. Ledbetter, W.J.A. Boersma, and E. Claassen. 1993. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions. J. Exp Med. 178:1555.
35. Caux, C., B. Vanbervliet, C. Massacrier, M. Azuma, K. Okumura, L. Lanier, and J. Banchereau. 1994. B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J. Exp Med. In press.
36. + T cell clones provides a costimulatory signal for human B cell activation. J. Exp Med. 177:1575.
37. Macchia, D., F. Almerigogna, P. Parronchi, A. Ravina, E. Maggi, and S. Romagnani. 1993. Membrane tumour necrosis factor-a is involved in the polyclonal B-cell activation induced by HIV-infected human T cells. Nature (Land.). 363:464.
38. Rodriguez, C., E. Roldan, G. Navas, and J.A. Brieva. 1993. Essential role of tumor necrosis factor-a in the differentiation of human tonsil in vivo induced B cells capable of spontaneous and high-rate immunoglobulin secretion. Eur. J. Immunol. 23:1160.
39. Larrick, J.W., and S.C. Wright. 1990. Cytotoxic mechanism of tumor necrosis factor-a. FASEB (Fed. Am. Soc Exp Bio.) J. 4:3215.
40. Hemandez-Caselles, T., and O. Stutman. 1993. Immune functions of tumor necrosis factor. I. Tumor necrosis factor induces apoptosis of mouse thymocytes and can also stimulate or inhibit IL-6-induced proliferation depending on the concentration of mitogenic costimulation. J. Immunol. 151:3999.
41. Matsue, H., P.D. Cruz, P.R. Bergstresser, and A. Takashima. 1992. Cytokine expression by epidermal cell subpopulations. J. Invest. Dermatol. 42:42.
42. + T cells through IL-12 produced by Listeria-induced macrophages. Science (Wash. DC). 260:547.
43. + T cells from a/8 TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFNy production is IFNy-dependent. Int. Immunol. 5:9.
44. Crowley, M.T., K. Inaba, M.D. Witmer-Pack, S. Gezelter, and R.M. Steinman. 1990. Use of the fluorescence activated cell sorter to enrich dendritic cells from mouse spleen. J. Immunol. Methods. 133:55.
45. Larsen, C.P., R.M. Steinman, W. Witmer-Pack, D.F. Hankins, P.J. Morris, and J.M. Austyn. 1990. Migration and maturation of Langerhans cells in skin transplants and explants. J. Exp Med. 172:1483.
46. O’Doherty, U., R.M. Steinman, M. Peng, P.U. Cameron, S. Gezelter, I. Kopeloff, W.J. Swiggard, M. Pope, and N. Bhardwaj. 1993. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimula-tory dendritic cells after culture in monocyte-conditioned medium. J. Exp Med. 178:1067.
47. Teunissen, M.B.M., J. Wormeester, S.R. Krieg, P.J. Peters, I.M.C. Vogels, M.L. Kapsenbeig, and J.D. Bos. 1990. Human epidermal Langerhans cells undergo profound morphological and phenotypical changes during in vitro culture. J Invest. Dermatol 94:166.
48. Gauchat, J.F., S. Henchoz, G. Mazzei, J.P. Aubry, T. Brunner, H. Blasey, P. Life, D. Talabot, L. Flores-Romo, J. Thompson, K. Kishi, J. Butterfield, C. Dahinden, and J.Y. Bonnefoy. 1993. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature (Lond.). 365:340.
49. Notarangelo, L.D., M. Duse, and A.G. Ugazio. 1992. Immunodeficiency with hyper-IgM (HIM). Immmodef. Rev 3:101.
50. + T lymphocytes. J. Immunol. 152:1523.