Antigenic Specificity of Porcine T Cell Response against Foot-and-Mouth Disease Virus Structural Proteins: Identification of T Helper Epitopes in VP1

Virology

Volumn 205, Issue 1, 1994, Pages 24-33

  Rodriguez, Ana ^a,d   Sáiz, Juan Carlos ^b   Novella, Isabel S ^c,e   Andreu, David ^c   Sobrino, Francisco ^a,b  

^a INIA   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; STRUCTURAL PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; EPITOPE MAPPING; FOOT AND MOUTH DISEASE VIRUS; HUMAN; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; SWINE; T LYMPHOCYTE;

ANIMAL; ANTIGENS, VIRAL; APHTHOVIRUS; CAPSID; EPITOPES; LYMPHOCYTE ACTIVATION; RECOMBINANT FUSION PROTEINS; SUPPORT, NON-U.S. GOV'T; SWINE; T-LYMPHOCYTES; VIRAL STRUCTURAL PROTEINS;

EID: 0028033245     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1006/viro.1994.1616     Document Type: Article

References (51)

1. Abou-Zeid, C., Filley, E., Steele, J., and Rook, G. A. W. (1987). A simple method for using antigens separated by polyacrilamide gel electrophoresis to stimulate lymphocytes in vitro after converting bands cut from western blots into antigen-bearing particles. J. Immunol. Methods 98, 5-10.
2. Bachrach, H. L, Moore, D. M., Mc Kerche, P. D., and Polatnick, J. (1975). Immune and antibody responses to an isolated capsid protein of food-and-mouth disease virus, J. Immunol. 115, 1636-1641.
3. Bachrach, H. L. (1977). Foot-and-mouth disease virus, properties, molecular biology and immunogenicity. In "Beltsville Symposia in Agricultural Research. I. Virology in Agriculture" (J. A. Romberger, Ed.), pp. 3-32. Allanheld, Osmun, Montclair, NJ.
4. Bahnemann, H. G. (1974). Binary ethylenimine as inactivant for foot and mouth disease virus and its application for vaccine production. Arch. Virol. 47, 47-56.
5. Barteling, S. J., and Vreeswijk, J. (1991). Development in foot-and-mouth disease vaccines. Vaccine 9, 75-88.
6. Bittle, J. L., Houghten, R. A., Alexander, H., Shinnick, T. M., Sutcliffe, J. G., Lener, R. A., Rowlands, D. J., and Brown, F. (1982). Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature (London) 298, 30-33.
7. Brown, F. (1992). New approaches to vaccination against foot-and- mouth disease. Vaccine 10, 1022-1026.
8. k)-restricted T cell repertoire for influenza hemagglutinin and antigenic drift. J. Exp. Med. 170, 383-397.
9. Capuchi, L, Brocci, E., De Simone, F., and Panina, J. F. (1984). Characterization of monoclonal antibodies produced against foot-and-mouth disease virus, pp. 32-39, "Session of the Research Group for the Standing Technical Commitee of the European Commission for the Control of Foot-and-Mouth Disease Virus, Brescia, Italy.
10. Clarke, B. E., Newton, S. E., Carroll, A. R., Francis, M. J., Appleyard, G., Syred, A. D., Highfield, P. E., Rowlands, D. J., and Brown, F. (1987). Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein. Nature 330, 381-384.
11. Collen, T. (1991). Ph. D. thesis. Council for National Academic Awards, England.
12. Collen, T., DiMarchi, R., and Doel, T. R. (1991). AT cell epitope in VP1 of foot-and-mouth disease virus is immunodominant for vaccinated cattle./Immunol. 146, 749-755.
13. Collen, T., and Doel, T. R. (1990). Heterotypic recognition of foot-and- mouth disease virus by cattle lymphocytes.J. Gen. Virol. 71, 309- 315.
14. DIez, J., DAvila, M., EscarmIs, C., Mateu, M. G., DomInguez, J., PErez, J. J., Giralt, E., Melero, J. A., and Domingo, E. (1990). Unique aminoacid substitutions in the capsid proteins of foot-and-mouth disease virus from a persistente infection in cell culture. J. Virol. 64, 5519-5528.
15. DiMarchi, R., Brooke, G., Gale, C., Cracknell, V., Doel, T. R., and Mowat, W, (1986). Protection of cattle against foot-and-mouth disease by a synthetic peptide. Science 232, 639-641.
16. Domingo, E., Mateu, M. G., Martinez, M. A., Dopazo, J., Moya, A., and Sobrino, F, (1990). Genetic variability and antigenic diversity of foot- and-mouth disease virus In "Applied Virology Research" (E. Kurstak, R. G, Marusyk, F. A. Murphy, and M. H. V. Van Regenmorten, Eds.), Vol. 2, pp. 233-259. Plenum, New York.
17. Dopazo, J., Rodriguez, A., Saiz, J. C., and Sobrino, F. (1993). Design of primers for PCR amplification of highly variable genomes. Comput. Appl. Biosci. 9, 123-125.
18. Fauchere, J. L, and Pliska, V. (1983). Hydrophobic parameters of amino acid side chains from the partitioning of A/-acetyl-amino acid amides. Eur I Med. Chem. 18, 1090-1093.
19. Francis, M. J., Fry, C. M., Rowlands, D. J., Brown, F., Bittle, J. L, Houghten, R. A., and Lerner, R. A. (1985). Immunological priming with synthetic peptides of foot-and-mouth disease virus. J. Gen. Virol. 66, 2347-2354.
20. Francis, M. J., Hastings, G. Z., Syred, A. D., McGinn, B., Brown, F., and Rowlands, D. J. (1987). Non-responsiveness to a foot-and-mouth disease virus peptide overcome by addition of foreign helper T-cell determinants. Nature 330, 168-170.
21. Francis, M. J., Hastings, G. Z., Clarke, B. E., Brown, A. L., Beddell, C. R., Rowlands, D. J., and Brown, F. (1990). Neutralizing antibodies to all seven serotypes of foot-and-mouth disease viurs elicited by synthetic peptides. Immunology 69, 171-176.
22. Gao, X. M., Liew, F. Y., and Tite, J. P. (1989), Identification and characterization of T helper epitopes in the nucleoprotein of influenza A virus. J. Immunol. 143, 3007-3014.
23. Hastings, G. Z., Francis, M. J., Rowlands, D. J., and Chain, B. M. (1993). Epitope analysis of the T cell response to a complex antigen: Proliferative responses to human rhinovirus capsids. Eur. j. Immunol. 23, 2300-2305.
24. Hunt, S. V. (1987). Preparation of lymphocytes and accesory cells. In "Lymphocytes, a practical approach" (G. G. B. Klaus, Ed.), pp. 1-32. IRL Press, Oxford.
25. Kimman, T. G., Bianchi, A. Y. J., Wensvoort, G., de Bruin, T. G. M., and Meliefste, C. (1993). Cellular immune response to Hog Cholera Virus (HCV): T cells of immune pigs proliferate in vitro upon stimulation with life HCV, but the envelope glycoprotein is not a major T-cell antigen. J. Virol. 67, 2922-2927.
26. Kleid, D. G., Yansura, D., Small, B., Dowbenko, D., Moore, D. M., Grub- man, M. J., Mc Kercher, P. D., Morgan, D. O., Robertson, B. H., and Bachrach, H. L. (1981), Cloned viral protein vaccine for foot and mouth disease: Responses in cattle and swine. Science 214, 1125-1129.
27. Kutubuddin, M., Simons, J., and Chow, M. (1992). Identification of T helper epitopes in the VP1 capsid protein of poliovirus. J. Virol. 66, 3042-3047.
28. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227, 680-685.
29. Laporte, J., Groschande, J., Wantyghem, J., Bernard, S., and Rouze, P. (1973). Neutralisation en culture cellulaire du pouvoir infectieux du virus de la fievre aphteuse par des sPrums provenant de pores immunises a I'aide d’une proteine virale purifie. C. R. Hebd. Sean. Acad. Sci. Paris 276, 3390-3401.
30. Leclerc, C., Deriaud, E., Mimic, V., and van der Werf, S. (1991). Identification of a T-cell epitope adjacent to neutralization site 1 of poliovirus type 1. J. Virol. 65, 711-178.
31. + T-cell clones. J. Virol. 66, 7012-7020.
32. Margalit, H., Spouge, J. L, Cornette, J. L, Cease, K. B., Delisi, C., and Berzofsky, J, A. (1987). Prediction of immunodominant helper T cell antigenic sites from the primary sequence. J. Immunol. 138, 2213-2229.
33. Mateu, M. G., Rocha, E., Vicente, O., Vayreda, F., Navalpotro, C., An- dreu, D., Pedroso, E., Giralt, E., Enjuanes, L, and Domingo, E. (1987). Reactivity with monoclonal antibodies of viruses from an episode of foot-and-mouth disease virus. Virus Res. 8, 261-274.
34. Mateu, M. G., MartInez, M. A., Rocha, E., Andreu, D., Parejo, J., Giralt, E., Sobrino, F., and Domingo, E. (1989). Implication of a quasispecies genome structure: effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus. Proc. Natl. Acad. Sci. USA 86, 5883-5887.
35. Mateu, M. G., MartInez, M. A., Capucci, L, Andreu, D., Giralt, E., Sobrino, F., Brocci, E., and Domingo, E. (1990). A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C. J. Gen. Virol. 71, 629-637.
36. Mateu, M. G., HernAndez, J., Feigelstock, D., Lea, S., PErez, J. J., Giralt, E., Stuart, D., Palma, E. L., and Domingo, E. (1994). Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites. J. Virol. 68, 1407-1417.
37. Merrifield, R. B. (1963). Solid phase synthesis. I. The synthesis of a tetrapeptide. J. Am. Chem. Soc. 85, 2149-2154.
38. Milich, D. R., McLahan, A., Moriati, A., and Thomson, G. B. (1987). A single 10-residue pre-s(1) peptide can prime T cell help for antibody production to multiple epitopes within the pre-s(1), pre-s(2), and s regions of HBsAg. J. Immunol. 138, 4457-4465.
39. Mills, K. H. G., Skehel, J. J., and Thomas, D. B. (1986). Extensive dever- sity in the recognition of influenza virus haemagglutinin by murine T helper clones. J. Exp. Med. 163, 1477-1490.
40. Palmenberg, A. C. (1989). Sequence aiigments of picornaviral capsid proteins. In "Molecular Aspects of Picornaviral Infection and Detection" (B. L. Semler and E. Ehrenfeld, Eds.), pp. 333-336. American Society for Microbiology, Washington.
41. Pereira, H. G. (1981). Foot-and-mouth disease. In "Virus Diseases of Food Animals" (E. P. J. Gibbs, Ed.), Vol. 2, pp. 333-363. Academic Press, London.
42. Remaut, E., Tsao, H., and Fiers, W. (1983). Improved plasmid vectors with a thermoinducible expression and temperature-regulated runaway replication. Gene 22, 103-113.
43. Rodriguez, A., MartInez-Salas, E., Dopazo, J., Davila, M., SAiz, J. C., and Sobrino, F. (1992). Primer design for specific diagnosis by PCR of highly variable RNA viruses: typing of foot-and-mouth disease virus. Virology 189, 363-367.
44. Rodriguez, A., Saiz, J. C., Sobrino, F., Submitted for publication.
45. Rothbard, J. B., and Taylor, W. R. (1988). A sequence pattern common to T cell epitopes. EMBO J. 7, 93-100.
46. Rueckert, R. R. (1990). Picornaviruses and their replication. In "Virology," (B. N. Fields and D. P. Knipe, Eds.), 2nd ed., pp. 507-548. Raven Press, New York.
47. Saiz, J. C., Gonzalez, M. J., Morgan, D. O., Card, J. L, Sobrino, F., and Moore, D. M. (1989). Antigenic comparison of different foot-and- mouth disease virus types using monoclonal antibodies defining multiple neutralizing epitopes on FMDV A5 subtypes. Virus Res. 13, 45-60.
48. SAiz, J. C., Rodriguez, A., GonzAlez, M., Alonso, F., and Sobrino, F. (1992). Heterotypic lympho pro I iterative response in pigs vaccinated with foot-and-mouth disease virus. Involvement of isolated capsid proteins. J. Gen. Virol. 73, 2601-2607.
49. Sobrino, F., Palma, E. L, Beck, E., DAvila, M., de la Torre, J. C., Negro, P., Villanueva, N., Ortin, J., and Domingo, E. (1986). Fixation of mutations in the vira! genome during an outbreak of foot-and-mouth disease: heterogeneity and rate variations. Gene 50, 149-159.
50. Strebel, K., Beck, E., Strohmaier, K., and Schaller, H. (1986). Characterization of foot-and-mouth disease virus gene products with antisera against bacterially synthesized proteins. J. Virol. 57, 983-991.
51. Van Bekkum, J. G. (1969). Correlation between serum antibody level and protection against challenge with FMD. "Session of Research Group of the Standing Technical Committee of the European Commission for the Control of Foot and Mouth Disease, Brescia, Italy," FAO.