Structural studies of the engrailed homeodomain

Protein Science

Volumn 3, Issue 10, 1994, Pages 1779-1787

  Clarke, Neil D ^a   Kissinger, Charles R ^b   Desjarlais, John ^c   Gilliland, Gary L ^d   Pabo, Carl O ^e  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AGOURON PHARMACEUTICALS INC   (United States)

^c DUPONT COMPANY   (United States)

^d NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

crystallography; homeodomain; protein stability; protein structure

Indexed keywords

DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN;

ARTICLE; CIRCULAR DICHROISM; CRYSTALLOGRAPHY; DENATURATION; DNA BINDING; DNA STRUCTURE; DROSOPHILA; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMODYNAMICS;

EID: 0028032397     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.5560031018     Document Type: Article

References (24)

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2. Extension of molecular replacement: A new search strategy based on Patterson correlation refinement
3. Crystallographic R factor refinement by molecular dynamics
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5. Accurate bond and angle parameters
6. Helix stop signals in proteins and peptides: The capping box
7. Use of an imaging proportional counter in macromolecular crystallography
8. Crystal structure of an engrailed homeodomain‐DNA complex at 2.8 Å resolution: A framework for understanding homeodomain‐DNA interactions
9. Crystal structure of the Oct‐1 POU domain bound to an octamer site: DNA recognition with tethered DNA binding modules
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11. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
12. DNA binding specificity of homeodomains
13. The interpretation of protein structures: Estimation of static accessibility
14. Crystallization and preliminary X‐ray diffraction studies of the engrailed homeodomain and of an engrailed homeodomain/DNA complex
15. Analysis of the relationship between side‐chain conformation and secondary structure in globular proteins
16. The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors
17. Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain
18. The structure and function of the homeodomain
19. Coupling of local folding to site‐specific binding of proteins to DNA
20. Electronic distributions within protein phenylalanine aromatic rings are reflected by the three‐dimensional oxygen atom environments
21. An efficient general‐purpose least‐squares refinement program for macromolecular structures
22. Structure of the HMG box motif in the B‐domain of HMG1
23. Crystal structure of a MATα2 homeodomain‐operator complex suggests a general model for homeodomain‐DNA interactions