Heat shock protein immunoreactivity in CSF: Correlation with oligoclonal banding and demyelinating disease

Neurology

Volumn 44, Issue 9, 1994, Pages 1644-1648

  Prabhakar, S ^a   Kurien, E ^b   Gupta, R ^c   Zielinski, S ^b   Freedman, M S ^d  

^a CHRISTIAN MEDICAL COLLEGE   (India)

^b MCGILL UNIVERSITY   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN G;

ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; DEMYELINATING DISEASE; ENCEPHALOMYELITIS; HUMAN; IMMUNOBLOTTING; MULTIPLE SCLEROSIS; PATHOGENESIS; PRIORITY JOURNAL;

ANTIBODIES; CHAPERONIN 60; DEMYELINATING DISEASES; ENCEPHALOMYELITIS, ACUTE DISSEMINATED; HUMANS; IMMUNOGLOBULINS; MULTIPLE SCLEROSIS; NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES;

EID: 0028030870     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/wnl.44.9.1644     Document Type: Article

References (25)

1. Young RA, Elliott TJ. Stress proteins, infection, and immune surveillance. Cell 1989;59:5–8.
2. Young RA. Stress proteins and immunology. Ann Rev Immunol 1990;8:401–420.
3. Cohen IR. Autoimmunity to chaperonins in the pathogenesis of arthritis and diabetes. Ann Rev Immunol 1991;9:567–589.
4. Tourtellotte WW, Baumhefner RW, Syndulko K, et al. The long march of the cerebrospinal fluid profile indicative of clinical definite multiple sclerosis; and still marching. J Neuroimmunol 1988;20:217–227.
5. Felgenhauer K, Schadlich H-J, Nekic M, Ackermann R. Cerebrospinal fluid antibodies, a diagnostic indicator for multiple sclerosis? J Neurol Sci 1985;71:291–299.
6. Warren KG, Catz I. Cerebrospinal fluid autoantibodies to myelin basic protein in multiple sclerosis patients: detection during first exacerbations and kinetics of acute relapses and subsequent convalescent phases. J Neurol Sci 1989;91:143–151.
7. Freedman MS, Buu NN, Ruijs TCG, Williams K, Antel JP. Differential expression of heat shock proteins by human glial cells. J Neuroimmunol 1992;41:231–238.
8. Freedman MS, Ruijs TCG, Selin LK, Antel JP. Peripheral blood -y-8 T cells lyse fresh human brain-derived oligodendrocytes. Ann Neurol 1991;30:794–800.
9. Selmaj K, Brosnan CF, Raine CS. Colocalization of lymphocytes bearing y5 T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis. Proc Natl Acad Sci USA 1991;88:6452–6456.
10. Wucherpfennig KW, Newcombe J, Li H, Keddy C, Cuzner ML, Hafler DA. yS T-cell receptor repertoire in acute multiple sclerosis lesions. Proc Natl Acad Sci USA 1992;89:4588–4592.
11. Poser CW, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227–231.
12. Dudani AK, Gupta RS. Immunological characterization of a human homologue of the 65-kilodalton mycobacterial antigen. Infect Immun 1989;57:2786–2793.
13. Jindal S, Dudani AK, Singh B, Harley CB, Gupta RS. Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65- kilodalton mycobacterial antigen. Mol Cell Biol 1989;9:2279–2283.
14. Vandvik B, Norrby E. Oligoclonal IgG antibody response in the central nervous system to different measles antigens in subacute sclerosing panencephalitis. Proc Natl Acad SciUSA 1973;70:1060–1063.
15. Roos RP. B-cell abnormalities in multiple sclerosis: a hypothesis. Arch Neurol 1985;42:73–75.
16. Kepes JJ. Large focal tumor-like demyelinating lesions of the brain: intermediate entity between multiple sclerosis and acute disseminated encephalomyelitis? A study of 31 patients. Ann Neurol 1993;33:18–27.
17. Kesselring J, Miller DH, Robb SA, et al. Acute disseminated encephalomyelitis: MRI findings and the distinction from multiple sclerosis. Brain 1990;113:291–302.
18. Hohlfeld R, Engel AG. Expression of 65-kd heat shock proteins in the inflammatory myopathies. Ann Neurol 1992;32:821–823.
19. Winfield JB, Jarjour WN. Stress proteins, autoimmunity, and autoimmune disease. Curr Top Microbiol Immunol 1991;167:161–189.
20. De Graeff-Meeder ER, Voorhorst M, Van Eden W, et al. Antibodies to the mycobacterial 65-kd heat-shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis. Am J Pathol 1990;137(5):1013–1017.
21. Schluesener HJ, Sobel RA, Linington C, Weiner HL. A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. J Immunol 1987;139:4016–4021.
22. Scolding NJ, Compston DAS. Oligodendrocyte-macrophage interactions in vitro triggered by specific antibodies. Immunology 1991;72:127–132.
23. − T helper cell lines that express the y/h T-cell receptor. Proc Natl Acad Sci USA 1990;87:7020–7024.
24. Hvas J, Oksenberg JR, Fernando R, Steinman L, Bernard CA. 78 T cell receptor repertoire in brain lesions of patients with multiple sclerosis. J Neuroimmunol 1993;46:225–234.
25. Cohen IR, Young DA. Autoimmunity, microbial immunity and the immunological homunculus. Immunol Today 1991;12:105–110.