New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs

Antimicrobial Agents and Chemotherapy

Volumn 38, Issue 12, 1994, Pages 2863-2870

  Pauwels, R ^a   Andries, K ^a   Debyser, Z ^a   Kukla, M J ^a   Schols, D ^a   Breslin, H J ^a   Woestenborghs, R ^a   Desmyter, J ^a   Janssen, M A C ^a   De Clerco, E ^a   Janssen, P A J ^a  

^a TIBOTEC BVBA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; BENZODIAZEPIN 2 ONE DERIVATIVE; DIDANOSINE; FOSCARNET; POLYCYTIDYLIC ACID; RIBAVIRIN; RNA DIRECTED DNA POLYMERASE; SAQUINAVIR; TIVIRAPINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL PROTECTION; DRUG ANTAGONISM; DRUG CYTOTOXICITY; DRUG POTENTIATION; HELPER CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS MUTANT;

EID: 0028029961     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.38.12.2863     Document Type: Article

References (0)