The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances

American Journal of Human Genetics

Volumn 55, Issue 5, 1994, Pages 1001-1018

  Reilly, Sharon L ^a   Ferrell, Robert E ^b   Sing, Charles F ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN B; APOLIPOPROTEIN C2; APOLIPOPROTEIN E; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ARTICLE; CORONARY ARTERY DISEASE; CORRELATION FUNCTION; COVARIANCE; FEMALE; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE;

ANALYSIS OF VARIANCE; APOLIPOPROTEINS; APOLIPOPROTEINS E; CHROMOSOME MAPPING; FEMALE; GENOTYPE; HUMANS; LIPIDS; MALE; MINNESOTA; POLYMORPHISM, GENETIC; RISK FACTORS; SEX CHARACTERISTICS;

EID: 0028028061     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (73)

1. Allen TFH, Hoekstra TW (1992) Toward a unified ecology. Columbia University Press, New York
2. Anderson K, Castelli WP, Levy D (1987) Cholesterol and mortality: 30 years of follow-up from the Framingham Study. JAMA 257:2176-2180
3. Anderson P (1971) More is different. Science 177:393-396
4. Atchley WR, Hall BK (1991) A model for development and evolution of complex morphological structures. Biol Rev 66:101-157
5. Badimon JJ, Fuster V, Chesebro JH, Badimon L (1993) Coronary atherosclerosis: a multifactorial disease. Circulation Suppl 87(3): II3-II16
6. Barker JSF, Thomas RH (1987) A quantitative genetic perspective on adaptive evolution. In: Loeschcke V (ed) Genetic constraints on adaptive evolution. Springer, Berlin, pp 3-23
7. Berg (1988) Variability gene effect on cholesterol at the Kidd blood group locus. Clin Genet 33:102-107
8. _ (1990) Level genes and variability genes in the etiology of hyperlipidemia and atherosclerosis. In: Berg K, Rettersol N, Refsum S (eds) From phenotype to gene in common disorders. Munksgaard, Copenhagen, pp 77-91
9. Boerwinkle E (1992) Genetics of plasma lipoprotein (a) concentrations. Curr Opin Lipid Res 3:128-136
10. Boerwinkle E, Visvikis S, Welsh D, Steinmitz J, Hanash SM, Sing CF (1987) The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals. Am J Med Genet 27:567-582
11. Bradshaw AD (1965) Evolutionary significance of phenotypic plasticity in plants. Adv Genet 13:115-155
12. Breslow J (1993) Genetics of lipoprotein disorders. Circulation Suppl 87(4):III16-III21
13. Carson ER, Cobelli C, Finkelstein L (1983) The mathematical modeling of metabolic and endocrine systems. John Wiley & Sons, New York
14. Childs B (1977) Persistent echoes of the nature-nurture argument. Am J Hum Genet 29:1-13
15. Clark AG (1987) Genetic correlations: the quantitative genetics of evolutionary constraints. In: Loeschcke V (ed) Genetic constraints on adaptive evolution. Springer, Berlin, pp 25-45
16. Crawford MA (1993) The role of essential fatty acids in neural development: implications for perinatal nutrition. Am J Clin Nutr Suppl 57:703S-710S
17. Camming AM, Robertson FW (1984) Polymorphism at the apoprotein-E locus in relation to risk of coronary disease. Clin Genet 25:310-313
18. Davignon J, Bouthillier D, Nestruck AC, Sing CF (1987) Apolipoprotein E polymorphism and atherosclerosis: insight from a study of octogenarians. Trans Am Clin Climatol Assoc 99: 100-110
19. Davignon J, Gregg RE, Sing CF (1988) Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 8:1-21
20. Efron B (1992) Six questions raised by the bootstrap. In: LePage R, Billard L (eds) Exploring the limits of bootstrap. John Wiley & Sons, New York, pp 99-126
21. Falconer DS (1989) Introduction to quantitative genetics, 3d ed. Longman Scientific & Technical, Essex
22. Ferrannini E (1991) Metabolic abnormalities of hypertension. Hypertension 18:636-639
23. Garrod AE (1902) The incidence of alkaptonuria: a study of chemical individuality. Lancet 2:1616-1620
24. _ (1908) Inborn errors of metabolism. Lancet 2:1-7
25. Grummer RR, Carroll DJ (1988) A review of lipoprotein cholesterol metabolism: importance to ovarian function. J Anim Sci 66:3160-3173
26. Hall P (1992) Efficient bootstrap simulation. In: LePage R, Billard L (eds) Exploring the limits of bootstrap. John Wiley & Sons, New York, pp 127-144
27. Hixson JE, PDAY research group (1991) Apolipoprotein E polymorphisms affects atherosclerosis in young males. Arterioscler Thromb 11:1237-1244
28. Hobbs HH, Leiterdorf E, Leffert CC, Cryer DR, Brown MS, Goldstein JL (1989) Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors. J Clin Invest 84:656-664
29. Hobbs HH, Russell DW, Brown MS, Goldstein JL (1990) The LDL receptor locus in familial hypercholesterolemia. Annu Rev Genet 24:133-170
30. Izzo C, Grillo F, Murador E (1981) Improved method for determination of high density lipoprotein cholesterol: isolation of high density lipoproteins by use of polyethylene glycol-6000. Clin Chem 27:371-374
31. Kamboh MI, Ferrell RE, Kottke BA (1988) Genetic studies of human apolipoproteins. V. A novel rapid procedure to screen apolipoprotein E polymorphism. J Lipid Res 29:1535-1543
32. Karlin S (1983) Association arrays in assessing forms of dependencies between bivariate random variables. Proc Natl Acad Sci USA 80:647-651
33. Kauffman SA (1993) The origins of order. Oxford University Press, New York
34. Kottke BA, Moll PP, Michels VV, Weidman WH (1991) Levels of lipids, lipoproteins, and apolipoproteins in a defined population. Mayo Clin Proc 66:1198-1208
35. Lusis AJ (1988) Genetic factors affecting blood lipoproteins. J Lipid Res 29:397-429
36. McKusick VA (1990) Mendelian inheritance in man: catalogs of autosomal dominant, autosomal recessive and X-linked phenotype. Johns Hopkins University Press, Baltimore
37. Mahley RW, Weisgraber KH, Innerarity TL, Rail SC (1991) Genetic defects in lipoprotein metabolism. JAMA 265:78-83
38. Meade TW (1987) The epidemiology of haemostatic and other variables in coronary artery disease. In: Verstraete M, Vermyler J, Lijnen HR, Arnout J (eds) Thrombosis and haemostasis. International Society on Thrombosis and Haemostasis and Leuven University Press, Leuven, pp 37-60
39. Moll PP, Michels VV, Weidman WH, Kottke BA (1989) Genetic determination of plasma apolipoprotein AI in a populationbased sample. Am J Hum Genet 44:124-139
40. Morrison DF (1980) Multivariate statistical methods. McGraw-Hill, New York
41. Murphy EA, Tojak JL (1986) The genetics of quantifiable homeostasis. Am J Med Genet 24:159-169
42. Oliver M (1976) Dietary cholesterol, plasma cholesterol, coronary heart disease. Br Heart J 38:214-218
43. Pearson K (1924) Tables for statisticians and biometricians. Part 2. Cambridge University Press
44. Pimm SL, Lawton JH, Cohen JE (1991) Food web patterns and their consequences. Nature 350:669-674
45. Reilly SL, Ferrell RE, Kortke BA, Kamboh MI, Sing CF (1991) The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on means and variances. Am J Hum Genet 49:1155-1166
46. Reilly SL, Ferrell RE, Kottke BA, Sing CF (1992) The genderspecific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, Minnesota. II. Regression relationships with concomitants. Am J Hum Genet 51:1311-1324
47. Reilly SL, Kottke BA, Sing CF (1990) The effects of generation and gender on the joint distributions of lipid and apolipoprotein phenotypes in the population at large. J Clin Epidemiol 43:921-940
48. Rose G (1985) Sick individuals and sick populations. Int J Epidemiol 14:32-38
49. Rose MR (1982) Antagonistic pleiotropy, dominance, and genetic variation. Heredity 48:63-78
50. Rosenman RH (1993) The independent roles of diet and serum lipids in the 20th-century rise and decline of coronary heart disease mortality. Integr Physiol Behav Sci 28:84-98
51. Ross R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:801-809
52. Salthe SN (1985) Evolving hierarchical systems. Columbia University Press, New York
53. Savageau MA (1976) Biochemical systems analysis: a study of function and design in molecular biology. Addison-Wesley, Reading, MA
54. Schlichting CD (1986) The evolution of phenotypic plasticity in plants. Annu Rev Ecol Syst 17:667-693
55. _ (1989) Phenotypic integration and environmental change. Bioscience 39:460-464
56. Simon HA (1962) The architecture of complexity. Proc Am Philos Soc 106:467-482
57. Sing CF, Davignon JD (1985) Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet 37:268-285
58. Sing CF, Haviland MB, Templeton AR, Zerba KE, Reilly SL (1992) Biological complexity and strategies for finding DNA variations responsible for inter-individual variation in risk of a common chronic disease, coronary artery disease. Ann Med 24:539-547
59. Sing CF, Moll PP (1990) Genetics of atherosclerosis. Annu Rev Genet 24:171-187
60. Sing CF, Orr JD (1976) Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh Michigan. III. Identification of genetic effects using twelve polymorphic genetic blood marker systems. Am J Hum Genet 28:453-464
61. Sing CF, Reilly SL (1993) Genetics of common diseases that aggregate, but do not segregate, in families. In: Sing CF, Hanis CL (eds) Genetics of cellular, individual, family, and population variability. Oxford University Press, New York
62. Sing CF, Zerba KE, Reilly SL (1994) Traversing the biological complexity in the hierarchy between genome and CAD end-points in the population at large. Clin Genet 46:4-16
63. Snedecor GW, Cochran WG (1971) Statistical methods. Iowa State University Press, Ames
64. Sniderman AD, Shapiro S, Marpole DG, Skinner BF, Teng B, Kwiterovich PO (1980) Association of coronary atherosclerosis with hypcrapobetalipoproteinemia (increased protein but normal cholesterol levels in human plasma low-density lipoproteins). Proc Natl Acad Sci USA 77:604-607
65. Sokal RR, Rohlf FJ (1981) Biometry, 2d ed. WH Freeman, New York
66. Strohman RC (1993) Ancient genomes, wise bodies, unhealthy people: limits of a genetic paradigm in biology and medicine. Perspect Biol Med 37:112-145
67. Tauber AI, Sarkar S (1992) The Human Genome Project: has blind reductiontsm gone to far? Perspect Biol Med 35:220-235
68. Turner ST, Weidman WH, Michels VV, Reed TJ, Ormson CL, Fuller T, Sing CF (1989) Distribution of sodium-lithium countertransport and blood pressure in Caucasians five to eight-nine years of age. Hypertension 13:378-391
69. Vega GL, Hobbs HH, Grundy SM (1991) Low density lipoprotein kinetics in a family having defective low density lipoprotein receptors in which hypercholesterolemia is suppressed. Arterioscler Thromb 11:578-585
70. Via S (1987) Genetic constraints on the evolution of phenotypic plasticity. In: Loeschcke V (ed) Genetic constraints on adaptive evolution. Springer, Berlin, pp 47-71
71. Waldrop (1992) Complexity: the emerging science at the edge of order and chaos. Simon & Schuster, New York
72. Weiss KM (1993) Genetic variation and human disease: principles and evolutionary approaches. Cambridge University Press, New York
73. Zerba KE, Sing CF (1993) The role of genome type-environment interaction and time in understanding the impact of genetic polymorphisms on lipid metabolism. Curr Opin Lipid Res 4: 152-162