GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GGDP AIF-4

Nature

Volumn 372, Issue 6503, 1994, Pages 276-279

  Sondek, John ^a   Lambright, David G ^a   Noel, Joseph P ^a   Hamm, Heidi E ^b,c   Sigler, Paul B ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; TRANSDUCIN; ALUMINUM DERIVATIVE; ALUMINUM FLUORIDE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; WATER;

ANIMAL TISSUE; ARTICLE; CATTLE; CRYSTAL STRUCTURE; ENZYME MECHANISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RETINA ROD OUTER SEGMENT; STEREOCHEMISTRY; ANIMAL; CHEMISTRY; COMPUTER GRAPHICS; GENETICS; HYDROLYSIS; METABOLISM; MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ANIMALIA; BOS TAURUS;

ALUMINUM COMPOUNDS; ANIMAL; CATTLE; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; FLUORIDES; GTP PHOSPHOHYDROLASES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; HYDROLYSIS; MUTAGENESIS; PROTEIN CONFORMATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSDUCIN; WATER;

EID: 0028027596     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/372276a0     Document Type: Article

References (30)

1. Sternweis, P.C, Gilman, A. G. Proc. natn. Acad. Sci. U.S.A. 79, 4888-4891 (1982).
2. Bigay, J., Deterre, P., Pfister, C., Chabre, M. FEBS Lett. 191, 181-185 (1985).
3. Higashijima, T., J. biol. Chem. 266, 3396-3401 (1991).
4. Noel, J.P, Hamm, H.E, Sigler, P. B. Nature 366, 654-663 (1993)
5. Lam bright, D.G, Noel, J.P, Hamm, H.E, Sigler, P. B. Nature 369, 621-628 (1994).
6. Westheimer, F. H. Science 235, 1173-1178 (1987).
7. Swain, C. G, Brown, J. F. Jr J. Am. chem. Soc. 74, 2538-2543 (1952).
8. Schepartz, A, Breslow, R. J. Am. Chem. Soc. 109, 1814-1826 (1987).
9. Goody, R. S., Phil. Trans. R. Soc. B336, 3-11 (1992).
10. Pai, E. F., EMBO J. 9, 2351-2359 (1990).
11. Schweins, T., Langen, R., Warshel, A. Nature struct. Biol. 1, 476-184 (1994).
12. Freeh, M., Biochemistry 33, 3237-3244 (1994).
13. Prive, G. G, Proc. natn. Acad. Sci. U.S.A. 89, 3649-3653 (1992).
14. Coleman, D. E., Science 265, 1405-1412 (1994).
15. Krengel, U., Cell 62, 539-548 (1990).
16. Antonny, B., Chardin, P., Roux, M., Chabre, M. Biochemistry 30, 8287-8295 (1991).
17. Polakis, P., McCormick, F. J. biol. Chem. 268, 9157-9160 (1993).
18. Freeh, M., Science 249, 169-171 (1990).
19. Lowy, D.R, Willumsen, B. M. A. Rev. 8/ocbem, 62, 851-891 (1993)
20. Der, C.J, Finkel, T, Cooper, G. M. Cell 44, 167-176 (1986).
21. Suarez, H. G., Oncogene 6, 677-679 (1991).
22. Landis, C. A., Nature 340, 692-696 (1989).
23. Chung, H.-H., Benson, D.R, Schultz, P, G. Science 259, 806-809 (1993).
24. Dupuis, A., Issartel, J., Vignals, P. V. FEBS Lett. 255, 47-52 (1989).
25. Maruta, S., Henry, G.D, Sykes, B.D, Ikebe, M. J. biol. Chem. 268, 7093-7100 (1993).
26. Stryer, L., Hurley, J.B, Fung, B. K.-K. Meth. Enzym. 96, 617-627 (1983).
27. Jones, T. A., Acta crystallogr. A47, 110-119 (1991).
28. Carson, M. J. appl. Crystallogr. 24, 958-961 (1991).
29. Fourquet, J. L, Plet, F., De Pape, F. Revue Chimie Min. 23, 183-190 (1986).
30. Grottel, M., Kozak, A., Maluszynska, H., Pajak, Z. J. Phys. Condens. Mat. 4, 1837-1848 (1992).