Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

Cell

Volumn 78, Issue 5, 1994, Pages 787-798

  Treier, Mathias ^a   Staszewski, Lena M ^a   Bohmann, Dirk ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN;

AMINO ACID SEQUENCE; ARTICLE; CARCINOGENESIS; CELL TRANSFORMATION; DNA BINDING; HELA CELL; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; TRANSCRIPTION INITIATION;

BACTERIA (MICROORGANISMS);

EID: 0028027308     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(94)90502-9     Document Type: Article

References (45)

1. The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells
2. The role of Jun Fos and the AP-1 complex in cell proliferation and transformation
3. Oncogene jun encodes a sequence-specific trans-activator similar to AP-1
4. The degradation signal in a short lived protein
5. Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ differences between v- and c-Jun
6. v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor
7. The cell-type-specific activator region of c-Jun juxtaposes constitutive and negatively regulated elements
8. Biochemical analysis of transcriptional activation by jun differential activity of c- and v-jun
9. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1
10. Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modifications in coding and noncoding sequences
11. A multiubiquitin chain is confined to a specific lysine in a targeted short-lived protein
12. Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor
13. Degradation of nuclear onco proteins by the ubiquitin system in vitro
14. Prolonged N-myc half-life in a neuroblastoma cell line lacking N-myc amplification
15. The fos oncogene
16. Epitope-tagged ubiquitin
17. Ubiquitination
18. Cyclin is degraded by the ubiquitin pathway
19. Ubiquitin-mediated protein degradation
20. The ubiquitin system for protein degradation
21. Degradation of transcription factors c-Jun and c-Fos by calpain
22. Ubiquitin and intracellular protein degradation
23. The short-lived MATα2 transcriptional regulator is ubiquitinated in vivo
24. New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues
25. Genetic approach to facilitate purification of recombinant proteins with a novel metal chelate adsorbent
26. The ubiquitin conjugating system
27. Structurefunction analysis of fos protein a single amino acid change activates the immortalizing potential of v-fos
28. A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture
29. A short amino acid sequence able to specify nuclear location
30. Mutations affecting the stability of the fushi tarazu protein in Drosophila
31. The Jun and Fos protein families are both required for cell cycle progression in fibroblasts
32. Induction of the oncogene jun/AP-1 by serum and TPA
33. A general method for rapid site-directed mutagenesis using the polymerase chain reaction
34. Selective arrangement of ubiquitinated and D1 proteincontaining nucleosomes within the Drosophila genome
35. Avian sarcoma virus 17 carries the jun oncogene
36. Amino acid substitutions modulate the effect of Jun on transformation transcriptional activation and DNA replication
37. Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptors
38. The yeast DOA4 gene encodes a deubiquitination enzyme related to a product of the human tre-2 oncogene
39. Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras
40. Amino acid sequences common to rapidly degraded proteins the PEST hypothesis
41. The E6 oncoprotein encoded by papillomavirus types 16 and 18 promotes degradation of p53
42. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
43. jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun
44. SWI5 instability may be necessary but is not sufficient for assymetric HO expression in yeast
45. Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences