Mutagenic selectivity at the hprt locus in v-79 cells: Comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,10-epoxide enantiomers with high and low carcinogenic activity

Carcinogenesis

Volumn 15, Issue 8, 1994, Pages 1729-1735

  Wei, S J C ^a   Chang, R L ^a   Hennig, E ^a   Cui, X X ^a   Merkler, K A ^a   Wong, C Q ^a   Yagi, H ^a,b,c   Jerina, D M ^a,b,c   Conney, A H ^a  

^a RUTGERS UNIVERSITY   (United States)

^b Laboratory of Bioorganic Chemistry   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 AZAGUANINE; ADENINE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; COMPLEMENTARY DNA; DIMETHYL SULFOXIDE; GUANINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL CULTURE; CELL STRAIN V 79; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENANTIOMER; EXON; FRAMESHIFT MUTATION; GENE AMPLIFICATION; GENE DELETION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; MUTAGENESIS; MUTATION RATE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMAL; BASE SEQUENCE; CELLS, CULTURED; COMPARATIVE STUDY; CRICETULUS; HAMSTERS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MOLECULAR SEQUENCE DATA; MUTATION; STEREOISOMERISM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028021450     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/15.8.1729     Document Type: Article

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