Effect of xylitol and sorbitol in chewing-gums on mutans streptococci, plaque ph and mineral loss of enamel

Caries Research

Volumn 28, Issue 1, 1987, Pages 48-54

  Wennerholm, K ^a   Arends, J ^b   Birkhed, D ^a   Ruben, J ^b   Emilson, C G ^a   Dijkman, A G ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Chewing gum; Enamel demineralization; Mutans streptococci; Plaque pH; Sorbitol; Xylitol

Indexed keywords

MINERAL; SORBITOL; XYLITOL;

ADULT; ARTICLE; BACTERIAL COUNT; CHEMISTRY; CHEWING GUM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENAMEL; HUMAN; ISOLATION AND PURIFICATION; LACTOBACILLUS; METABOLISM; MICROBIOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PH; RANDOMIZED CONTROLLED TRIAL; SALIVA; SECRETION; STREPTOCOCCUS MUTANS; TOOTH DISEASE; TOOTH PLAQUE;

ADULT; CHEWING GUM; COLONY COUNT, MICROBIAL; DENTAL ENAMEL; DENTAL PLAQUE; DENTAL PLAQUE INDEX; DOUBLE-BLIND METHOD; HUMANS; HYDROGEN-ION CONCENTRATION; LACTOBACILLUS; MINERALS; SALIVA; SECRETORY RATE; SORBITOL; STREPTOCOCCUS MUTANS; TOOTH DEMINERALIZATION; XYLITOL;

EID: 0028018564     PISSN: 00086568     EISSN: None     Source Type: Journal    
DOI: 10.1159/000261620     Document Type: Article

References (42)

1. Aguirre-Zero O, Zero DT, Proskin HM: Effect of chewing xylitol chewing gum on salivary flow rate and the acidogenic potential of dental plaque. Caries Res 1993;27:55-59.
2. Arends J, Christoffersen J, Schuthof J, Smits MT: Influence of xylitol on demineralization of enamel. Caries Res 1984;18:296-301.
3. Arends J, Gelhard TBFM: In vivo remineralisation of human enamel: in Leach SA. Edgar WM (eds): Demineralisation and Remineralisation of the Teeth. Oxford, IRL Press. 1983. pp-1-16.
4. Assev S, Rolla G: Sorbitol increases the growth inhibition of Strep, mutans OMZ176. Acta Pathol Microbiol Immunol Scand Sect. [B] 1986;94:231-237.
5. Bär A: Caries prevention with xylitol: A review of scientific evidence. World Rev Nutr Diet 1988;55:183-209.
6. Birkhed D, Bär A: Sorbitol and dental caries. World Rev Nutr Diet 1991;65:1-37.
7. Birkhed D, Edwardsson S, Svensson B, Moskovitz F, Frostell G: Acid production from sorbitol in human dental plaque. Arch Oral Biol 1978;23:971-975.
8. Birkhed D, Edwardsson S, Wikesjö U, Ahldén M-L, Ainamo J: Effect of 4 days consumption of chewing gum containing sorbitol or a mixture of sorbitol and xylitol on dental plaque and saliva. Caries Res 1983;17:76-88.
9. Creanor SL, Strang R, Gilmour WH, Foye RH, Brown J, Geddes DAM, Hall AF: The effect of chewing gum use on in situ enamel lesion remineralisation. J Dent Res 1992;71:1895-1900.
10. Dijkman A, Huizinga E, Ruben J, Arends J: Remineralization of human enamel in situ after 3 months: The effect of not brushing versus the effect of an F dentifrice and an F-free dentifrice. Caries Res 1990;24:263-266.
11. Dijkman AG, Schuthof J, Arends J: In vivo remineralization of plaque-induced initial enamel lesions - A microradiographic investigation. Caries Res 1986;20:202-208.
12. Dodds MWJ, Hsich SC, Johnsson DA: The effect of increased mastication by daily gum-chewing on salivary gland output and dental plaque acidogenicity. J Dent Res 1991;70:1474-1478.
13. Edgar WM, Geddes DAM: Chewing gum and dental health - A review. Br Dent J 1990;168:173-177.
14. Emilson CG: Prevalence of Streptococcus mutans with different colonial morphologies in human plaque and saliva. Scand J Dent Res 1983;91:26-32.
15. Ericsson Y: Clinical investigations on the salivary buffering action. Acta Odontol Scand 1959;17:131-165.
16. Gold OG, Jordan HV, van Houte J: A selective medium for Streptococcus mutans. Arch Oral Biol 1973;18:1357-1364.
17. Heintze U, Birkhed D, Björn H: Secretion rate and buffer effect of resting and stimulated whole saliva as a function of age and sex. Swed Dent J 1983;7:227-238.
18. Jenkins GN, Edgar WM: The effect of daily gum chewing on salivary flow rates in man. J Dent Res 1989;68:786-790.
19. de Josselin de Jong E, van der Linden AHIM, ten Bosch JJ: Longitudinal microradiography: A non-destructive automated quantitative method to follow mineral changes in mineralised tissue slices. Phys Med Biol 1987;32:1209-1220.
20. Kalfas S: Sorbitol and dental plaque: Aspects of caries-related microbiological and biochemical factors. Swed Dent J 1989 (suppl 63).
21. Kalfas S, Svensäter G, Birkhed D, Edwardsson S: Sorbitol adaptation of dental plaque in people with low and normal salivary-secretion rates. J Dent Res 1990;69:442-446.
22. Kandelman D, Gagnon G: A 24-month clinical study of the incidence and progression of dental caries in relation to consumption of chewing gum containing xylitol in school preventive programs. J Dent Res 1990;69:1771-1775.
23. Leach SA, Lee GTR, Edgar WM: Remineralization of artificial caries-like lesions in human enamel in situ by chewing sorbitol gum. J Dent Res 1989;68:1064-1068.
24. Lingström P, Imfeld T, Birkhed D: Comparison of three different methods for measurement of plaque-pH in humans after consumption of soft bread and potato chips. J Dent Res 1993;72:865-870.
25. Loesche WJ, Grossman NS, Earnest R, Corpron R: The effect of chewing xylitol gum on the plaque and saliva levels of Streptococcus nutans. J Am Dent Assoc 1984;108:587-592.
26. Mäkinen KK, Bennett CA, Isokangas P, Isotupa K, Pape HJ, Hujoel PP, Mäkinen P-L: Cariespreventive effect of polyol-containing chewing gums (abstract). J Dent Res 1993;72:346.
27. Mäkinen KK, Isokangas P: Relationship between carbohydrate sweeteners and oral diseases. Proc Food Nutr Sci 1988;12:73-109.
28. Manning RH, Edgar WM: Salivary stimulation by chewing gum and its role in the remineralisation of caries-like lesions in human enamel in situ. J Clin Dent 1992;3:71-74.
29. Manning RH, Edgar WM, Agalamanyi EA: Effects of chewing gums sweetened with sorbitol or a sorbitol/xylitol mixture on the remineralisation of human enamel lesions in situ. Caries Res 1992;26:104-109.
30. Möller AJR: Microbiological examination of root canals and periapical tissue of human teeth. Odontol Tidskr 1966:74 (special issue).
31. Mouton C, Scheinin A, Makinen KK: Effect on plaque of a xylitol-containing chewing-gum: A pilot study. Acta Odontol Scand 1975a;33:27-31.
32. Mouton C, Scheinin A, Makinen KK: Effect on plaque of a xylitol-containing chewing-gum: A clinical and biochemical study. Acta Odontol Scand l975b;33:33-40.
33. Mouton C, Scheinin A, Makinen KK: Effect of a xylitol chewing gum on plaque quantity and quality. Acta Odontol Scand I975c;33:251-257.
34. Øgaard B, Arends J. Schuthof J, Rolla G, Ekstrand J, Oliveby A: Action of fluoride on initiation of early enamel caries in vivo. A microradiographical investigation. Caries Res 1986;20:270-277.
35. Rekola M, Laikko I, Anttinen H, Scheinin A, Makinen KK: Die Wirkung xylit- und sorbithaltiger Kaugummis auf Plaque und Speichel, I. Klinische Aspekte. Kariesprophylaxe 1980;2:21-27.
36. Scheie AA, Fejerskov O, Lingstrom P, Birkhed D, Manji F: Use of palladium touch microelectrodes under field conditions for in vivo assessment of dental plaque pH in children. Caries Res 1992;26:44-52.
37. Silness J, Löe H: Periodontal disease in pregnancy, II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-135.
38. Smits MT, Arends J: Influence of xylitol- and/or fluoride-containing toothpastes on the remineralization of surface softened enamel defects in vivo. Caries Res 1985;19:528-535.
39. Soderling E, Makinen KK, Chen C-Y, Pape HR Jr. Loesche W, Mäkinen P-L: Effect of sorbitol, xylitol and xylitol/sorbitol chewing gums on dental plaque. Caries Res 1989;23:378-384.
40. Syed SA, Loesche WJ: Survival of human dental plaque flora in various transport media. Appl Microbiol 1972;24:638-644.
41. Topitsoglou V, Birkhed D, Larsson L-Å, Frostell G: Effect of chewing gums containing xylitol, sorbitol or a mixture of xylitol and sorbitol on plaque formation, pH changes and acid production in human dental plaque. Caries Res 1983;17:369-378.
42. Waaler SM, Rolla G, Assev S: Adaptation of dental plaque to sorbitol after 3 months’ exposure to chewing gum. Scand J Dent Res 1993;101:84-86.