Effect of seven new vasoactive immunoconjugates on the enhancement of monoclonal antibody uptake in tumors

Cancer

Volumn 73, Issue 3 S, 1994, Pages 824-831

  Khawli, Leslie A ^a   Miller, Gordon K ^a   Epstein, Alan L ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

biodistribution; blood flow; monoclonal antibodies; vasopermeability

Indexed keywords

ANTIBODY CONJUGATE; BRADYKININ; HISTAMINE; IMMUNOGLOBULIN F(AB')2 FRAGMENT; INTERLEUKIN 2; LEUKOTRIENE B4; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY TNT 1; PHYSALAEMIN; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASOACTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD VESSEL PERMEABILITY; CANCER IMMUNOTHERAPY; CANCER TRANSPLANTATION; CONFERENCE PAPER; CONJUGATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG UPTAKE; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RADIOIODINATION; TUMOR BLOOD FLOW; UTERINE CERVIX CARCINOMA;

ANIMAL; ANTIBODIES, MONOCLONAL; BLOOD VESSELS; CAPILLARY PERMEABILITY; CERVIX NEOPLASMS; FEMALE; HUMAN; LEUKOTRIENE B4; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; SUPPORT, U.S. GOV'T, P.H.S.; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 0028013236     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(19940201)73:3+<824::AID-CNCR2820731312>3.0.CO;2-V     Document Type: Article

References (48)

1. Radioimmunodetection in cancer identification
2. Tumor therapy with radiolabeled monoclonal antibodies
3. Monoclonal antibody imaging: clinical and technical perspectives
4. Problems and prospects for radioimmunodetection and radioimmunotherapy of cancer
5. Targeting of cancer with radiolabeled antibodies
6. Limitations of radiolabeled monoclonal antibodies for localization of human neoplasms
7. Multiple‐drug resistance in human cancer
8. Mechanisms and clinical significance of multidrug resistance
9. Enhanced tumor uptake of macromolecules induced by a novel vasoactive interleukin‐2 immunoconjugate
10. A novel method for the detection of necrotic lesions in human cancers
11. Tumor necrosis treatment of ME‐180 human cervical carcinoma model with 1–131 labeled TNT‐1 monoclonal antibody
12. A comparative autoradiographic study demonstrating differential intratumor localization of monoclonal antibodies to cell surface (Lym‐1) and intracellular (TNT‐1) antigens
13. Molecular weight of recombinant human tumor necrosis factor‐α
14. Recombinant human tumor necrosis factor‐α: effects on proliferation of normal and transformed cells in vitro
15. Tumor necrosis factor enhances the neutrophil‐dependent increase in endothelial permeability
16. Tumor necrosis factor‐α induces neutrophil‐mediated injury of cultured human endothelial cells
17. Interleukin‐1 and interleukin‐1 antagonism
18. The numerous postulated biological manifestations of interleukin‐1
19. The action of physalaemin on the systemic arterial blood pressure of some experimental animals
20. Physalaemin: an amphibian tachykinin in human lung small‐cell carcinoma
21. Histamine: an early messenger in inflammatory and immune reactions
22. Studies on inflammation: the effect of histamine and serotonin on vascular permeability: an electron microscopic study
23. On the mechanism of vascular leakage caused by histamine‐type mediators: a microscopic study in vivo
24. Kinin‐forming enzymes in vascular tissue
25. Leukotrienes and other products of the 5‐lipoxygenase pathway
26. 4 metabolite
27. Cell based radioimmunoassays to quantitate the immunoreactivity of TNT monoclonal antibodies directed against intracellular antigens
28. Enhancement of N‐hydroxysulfosuccinimide of water‐soluble carbodiimide‐mediated coupling reactions
29. A live cell enzyme‐linked immunosorbent assay for detecting human hepatoma membrane antigens
30. Studies on the conjugation of leukotriene B4 with proteins for development of a radioimmuno‐assay for leukotriene B4
31. Molecular and cellular properties of human polymorphonuclear leukocytes receptors for leukotriene B4
32. Studies on the inhibition of glyoxalase I by S‐substituted glutathiones
33. Labeling of plasma proteins with radioactive iodine
34. Vascular volume and perme ability of human and murine tumors grown in athymic mice
35. Radioiodinated monoclonal antibody conjugates: Synthesis and comparative evaluation
36. Endothelial activation during interleukin 2 immunotherapy: A possible mechanism for the vascular leak syndrome
37. Local cytokine availability elicits tumor rejection and systemic immunity through granulocyte‐T‐lymphocyte cross‐talk
38. Antibody‐mediated delivery of tumor necrosis factor (TNF‐α): Improvement of cytotoxicity and reduction of cellular resistance
39. In vivo studies with covalent conjugates of cobra venom factor and monoclonal antibodies to human tumors
40. Antibody conjugates without inherent toxicity: The targeting of cobra venom factor and other biological response modifiers
41. Monocyte chemotaxis mediated by formyl‐methionyl‐leucyl‐phenylalanine conjugated with monoclonal antibodies against human ovarian carcinoma
42. Interferon‐conjugation to human osteogenic sarcoma monoclonal antibody 79IT/36
43. Immunomo‐dulation: NK cells activated by interferon‐conjugated monoclonal antibody against human osteosarcoma
44. Inflammatory changes in tumor vessels after systemic 5‐hydroxytryptamine, bradykinin, kallikrein, or lysolecithin
45. Evaluation of biological response modifiers in the enhancement of tumor uptake of technetium‐99m labeled macro‐molecules
46. Histamine, leukotriene C4, and interleukin‐2 increase antibody uptake into a human carcinoma xenograft model
47. Vascular permeability and interstitial diffusion of macromolecules in the hamster cheek pouch: effects of vasoactive drugs
48. Preclinical and clinical studies with a variety of immunoconjugates