Somatic Mutation: From the dark zone to the light

Current Biology

Volumn 4, Issue 1, 1994, Pages 70-72

  MacLennan, I C M ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN;

ANIMAL; ANTIBODY PRODUCTION; B LYMPHOCYTE; BIOLOGICAL MODEL; BIOSYNTHESIS; CYTOLOGY; GENETICS; HUMAN; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MUTATION; REVIEW; SPLEEN; T LYMPHOCYTE;

ANIMAL; ANTIBODY FORMATION; ANTIGENS; B-LYMPHOCYTES; GENES, IMMUNOGLOBULIN; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; MODELS, BIOLOGICAL; MUTATION; SPLEEN; T-LYMPHOCYTES;

ANIMALIA;

EID: 0028005612     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00017-8     Document Type: Article

References (13)

1. Molecular events during maturation of the immune response to oxazalone
2. Virgin B-cell recruitment and the lifespan of memory during antibody responses to DNP-hemocyanin
3. Germinal centers develop oligoclonally
4. Sites of specific B-cell activation in primary and secondary responses to T-cell-dependent and T-cell-independent antigens
5. Germinal centres
6. Mechanisms of antigen-driven selection in germinal centres
7. Intraclonal generation of antibody mutants in germinal centers
8. Maturation of the immune response in germinal centres
9. Analysis of somatic mutation activity in multiple Vκ genes in the response to 2-phenyl-5-oxazalone
10. Quantitative analysis of molecules which distinguish functional compartments in germinal centres
11. The evolution of B cells from virgin to memory
12. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periartcriolar lymphoid sheath-associated foci and germinal centers