Regulation of gene expression by transcription factors Ets‐1 and Ets‐2

Molecular Reproduction and Development

Volumn 39, Issue 2, 1994, Pages 208-214

  J Tymms, Martin ^a   Kola, Ismail ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

DNA binding domain; ETS; Ets 1; Ets 2

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CD4 ANTIGEN; CELL PROTEIN; COLLAGENASE; CYTOKERATIN; CYTOKINE; GLYCOPROTEIN IIB; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; STROMELYSIN; T LYMPHOCYTE RECEPTOR; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSCRIPTION FACTOR; TRANSFERASE; UROKINASE;

ANIMAL CELL; CELL CYCLE; CHICK EMBRYO; CONFERENCE PAPER; CONTROLLED STUDY; DNA BINDING; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; GENE EXPRESSION REGULATION; MOLECULAR GENETICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RETROVIRUS; T LYMPHOCYTE ACTIVATION; TISSUE SPECIFICITY; TRANSACTIVATION; TRANSCRIPTION REGULATION; VIRUS CELL TRANSFORMATION;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BINDING SITES; COMPARATIVE STUDY; DNA; EMBRYO AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION; HUMAN; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TATA BOX; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; XENOPUS LAEVIS;

ANIMALIA; GALLUS GALLUS; UNIDENTIFIED RETROVIRUS;

EID: 0028003932     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.1080390214     Document Type: Review

References (51)

1. Influence of nucleotides flanking the ‐GGAA‐ core sequence on ETS1 and ETS2 DNA‐binding activity and the mechanism of ETS1 autoregulation
2. Transactivation of erythroid transcription factor GATA‐1 by a myb‐ets‐containing retrovirus
3. Temporal and tissue‐specific expression of mouse ets genes
4. Expression of ets genes in mouse thymocyte subsets and T‐cells
5. Reciprocal expression of human ETS1 and ETS2 genes during T‐cell activation: Regulatory role for the protooncogene ETS1
6. A single amino‐acid substitution in the Ets domain alters core DNA binding specificity of Ets to that of the related transcription factors Elf1 and E74
7. Rapid and transient expression of Ets‐2 in mature macrophages following stimultion with cMFG, LPS, and PKC activators
8. A polyomavirus enhancer A‐binding protein‐3 site and Ets‐2 protein have a major role in the 12‐O‐tetradecanoylphorbol‐13‐acetate response of the human stromelysin gene
9. Requirement of ets2 expression for Xenopus oocyte maturation
10. Localization of the c‐ets‐2 transactivation domain
11. Mechanism of c‐myc regulation of c‐Myb in different cell lineages
12. The various domains of v‐myb and v‐ets oncogenes of E26 retrovirus contribute differently, but cooperatively, in transformation of hematopoietic lineages
13. Myb and Ets proteins cooperate in the transcriptional activation of the mim‐1 promoter
14. Both LyF‐1 and an Ets protein interact with a critical promoter element in the murine terminal transferase gene
15. The role of c‐myc in cell growth
16. Functional analysis of c‐Myb protein in T‐lymphocytic cell lines shows that it trans‐activates the c‐myc promoter
17. Highaffinity DNA‐protein interactions of the cellular ETS1 protein: The determination of the ETS binding motif
18. cEts‐1 protein is hyperphosphorylated during mitosis
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20. The activation domain of transcription factor PU. binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB
21. An inhibitory carboxyl‐terminal domain in Ets‐1 and Ets‐2 mediates differential binding of ETS family factors to promoter sequences of the mb‐1 gene
22. The human ETS1 gene: Genomic structure, promoter characterization and alternative splicing
23. Isoforms of human ets‐1 protein: generation by alternative splicing and differential phosphorylation
24. The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation
25. c‐myb transactivates cdc2 expression via Myb binding sites in the 5′flanking region of the human cdc2 gene
26. Mitogenic signaling by colony‐stimulating factor 1 and ras is suppressed by the ets‐2 DNA‐binding domain and restored by myc overexpression
27. c‐ets‐1 DNA binding to the PEA3 motif is differentially inhibited by all the mutations found in v‐ets
28. Serum, AP‐1 and Ets‐1 stimulate the human ets‐1 promoter
29. Positive and negative factors regulate the transcription of the ETS2 gene via an oncogene‐responsive‐like unit within the ETS2 promoter region
30. The human ETS‐2 gene promoter: molecular dissection and nuclease hypersensitivity
31. v‐myb and v‐ets transform chicken erythroid cells and cooperate both in trans and cis to induce distinct differentiation phenotypes
32. Regulation of lymphoid‐specific immunoglobulin mu heavy chain gene enhancer by ETS‐domain proteins
33. The c‐ets‐1 protein is chromatin associated and binds to DNA in vitro
34. Structure, expression and alternative splicing of the human c‐ets‐1 proto‐oncogene
35. Ets proteins: New factors that regulate immunoglobulin heavy‐chain gene expression
36. Single‐cell detection of ets‐1 transcripts in human neuroectodermal cells
37. Characterization of the human CD4 gene promoter: Transcription from the CD4 gene core promoter is tissue‐specific and is activated by Ets proteins
38. c‐ets‐2 protooncogene has mitogenic and oncogenic activity
39. Transactivation of GATA‐1 promoter with ETS1, ETS2 and ERGB/Hu‐FLI‐1 proteins: Stabilization of the ETS1 protein binding on GATA‐1 promoter sequences by monoclonal antibody
40. A conserved AU sequence from the 3′ untranslated region of GM‐CSF mRNA mediates selective mRNA degradation
41. The c‐ets‐1 proto‐oncogenes in Xenopus laevis: Expression during oogenesis and embryogenesis
42. Common features in DNA recognition helices of eukaryotic transcription factors
43. cis‐Acting sequences required for inducible interleukin‐2 enhancer function bind a novel Ets‐related protein, Elf‐1
44. Complementary pattrens of expression of c‐eta‐1. c‐myb and c‐myc in the blood forming system of the chick embryo
45. Evolutionarily conserved Ets family members display distinct DNA binding specificities
46. Regulation of the Ets‐related transcription factor Elf‐1 by binding to the retinoblastoma protein
47. PEA3 is a nuclear target for transcription activation by non‐nuclear oncogenes
48. The c‐ets proto‐oncogenes encode transcription factors that cooperate with c‐Fos and c‐Jun for transcriptional activation
49. The Ets family of transcription factors
50. Molecular organization and differential polyadenylation sites of the human ETS2 gene
51. c‐ets 1 proto‐oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans