Octreotide therapy of large-volume refractory AIDS-associated diarrhea: A randomized controlled trial

AIDS

Volumn 8, Issue 11, 1994, Pages 1563-1567

  Garcia Compean, Diego ^a,b   Ramos Jimenez, Javier ^a   Guzman De La Garza, Francisco ^a   Saenz, Corando ^a   Maldonado, Hector ^a   Barragan, Rodrigo F ^a   Michel, Henri ^b  

^a UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

^b HÔPITAL SAINT ELOI   (France)

Author keywords

AIDS; HIV; Octreotide; Refractory diarrhea; Sandostatin; Somatostatin

Indexed keywords

DIPHENOXYLATE; ITRACONAZOLE; LOPERAMIDE; OCTREOTIDE; PLACEBO; SOMATOSTATIN DERIVATIVE;

ABDOMINAL PAIN; ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE ASSOCIATION; FECES ANALYSIS; HUMAN; HUMAN TISSUE; INJECTION PAIN; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PARESTHESIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; VOMITING;

EID: 0027999248     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199411000-00007     Document Type: Article

References (22)

1. Garcia Compean D, Tinoco JC, Alcocer J, Uribe M: High frequency of diarrhea in Mexican patients with AIDS [abstract]. Dig Dis Sci 1986, 31:433S.
2. Smith PD: Infectious diarrhea in patients with AIDS: Gastroenterol Clin North Am 1993, 22:535-548.
3. Smith PD, Lane HC, Gill VJ, et al.: Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS). Etiology and response to therapy. Ann Intern Med 1988, 108:328-333.
4. Johanson JF, Sonnenberg A: Efficient management of diarrhea in the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1990, 112:942-948.
5. Bartlett JG, Belitsos PC, Sears CI: AIDS enteropathy. Clin Infect Dis 1992, 15:726-735.
6. Ullrich R, Zeitz M, Heise W, L'Age M, Hoffken G, Reichken EO: Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): evidence for HIV-induced enteropathy. Ann Intern Med 1989, 111:15-21.
7. Grosman I, Simon D: Potential gastrointestinal uses of somatostatin and its synthetic analogue octreotide. Am J Gastroenterol 1990, 85:1061-1072.
8. Cook DJ, Kelton JG, Stanisz DM, Collins S: Somatostatin treatment for cryptosporidial diarrhea in a patient with the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1988, 108:708-709.
9. Robinson EN, Fogel R: A somatostatin analogue and diarrhea in the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1988, 109:680-681.
10. Katz MD, Erstad BL, Rose C: Treatment of severe cryptosporidium-related diarrhea with octreotide in a patient with AIDS. Drug Intell Clin Pharm 1988, 22:134-136.
11. Moroni M, Franzetti F, Carosi GP, et al.: Effect of octreotide treatment in patients with refractory AIDS-associated diarrhea [abstract]. Gastroenterology 1991, 100:A601.
12. Garcia Compean D, Ramos Jimenez J, Marfil-Rivera J, Guzman De La Garza FJ, Barragan RF. Severe diarrhea in AIDS treated with a somatostatin analog. Report of a case. Rev Gastroenterol Mex 1992, 57:41-44.
13. Fanning M, Monte M, Sutherland LR, Broadhead M, Murphy G, Harris A: Pilot study of sandostatin (octreotide) therapy of refractory HIV-associated diarrhea. Dig Dis Sci 1991, 36:476-480.
14. Cello JP, Grendel JH, Basuk P, et al.: Effect of octreotide on refractory AIDS-associated diarrhea. A prospective, mufticenter clinical trial. Ann Intern Med 1991, 115:705-710.
15. Chen F, O'Dorisio MS, Hermann G, Hayes J, Malarkey WB, O'Dorisio TM: Mechanism of action of long acting analogs of somatostatin. Regul Pept 1993, 44:285-295.
16. Simon D, Weiss LM, Brandt LJ: Treatment options for AIDS related esophageal and diarrhea disorders. Am I Gastroenterol 1992, 87:274-281.
17. Kotler DP, Gaetz HP, Lange M, Klein EB, Holt PR: Enteropathy associated with the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1984, 33:421-428.
18. Ruff MR, Martin BM, Ginns EI, Ferrar WL, Pert CB: CD4 receptor-binding peptides that block HIV infectivity cause human monocyte chemotaxis. FEBS Lett 1987, 211:17-22.
19. Manfredi R, Vezzadini P, Costigliola P, Ricchi E, Fanti MP, Chiodo F: Elevated plasma levels of vasoactive intestinal peptide in AIDS patients with refractory idiopathic diarrhoea. Effects of treatment with octreotide. AIDS 1993, 7:223-226.
20. Batman PA, Miller AR, Forster SM, Harris JR, Pinching AJ, Griffin GE: Jejunal enteropathy associated with human immunodeficiency virus infection: quantitative histology. J Clin Pathol 1989, 42:275-281.
21. Laughon BE, Druckman DA, Vernon A, et al.: Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology 1988, 94:984-993.
22. Londony W, Angerer M, Kutz K, Landgraf R, Londony V: Diminishing efficacy of octreotide (SMJ 201-995) on gastric functions of healthy subjects during one week administration. Gastroenterology 1989, 96:713-722.