Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet

Journal of Clinical Investigation

Volumn 94, Issue 6, 1994, Pages 2414-2420

  Makita, Keiko ^a   Takahashi, Kihito ^a   Karara, Armando ^a   Jacobson, Harry R ^a   Falck, John R ^b   Capdevila, Jorge H ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

arachidonic acid; blood pressure; Dahl rats; epoxyeicosatrienoic acids; sodium chloride

Indexed keywords

ARACHIDONIC ACID; CLOTRIMAZOLE; CYTOCHROME P450; INDOMETACIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; HYPERTENSION; MATERNAL HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SALT INTAKE; SODIUM EXCRETION;

EID: 0027996820     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI117608     Document Type: Article

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