MDM2 gene amplification in human breast cancer

European Journal of Cancer

Volumn 30, Issue 7, 1994, Pages 982-984

  Quesnel, B ^a,b   Preudhomme, C ^a,b   Fournier, J ^c   Fenaux, P ^a   Peyrat, J P ^c  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b Institut de Recherche sur le Cancer de Lille   (France)

^c CENTRE OSCAR LAMBRET   (France)

Author keywords

breast cancer; gene amplification; MDM2; oestradiol receptor

Indexed keywords

ESTROGEN RECEPTOR;

ARTICLE; BREAST CANCER; FEMALE; GENE AMPLIFICATION; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

BLOTTING, SOUTHERN; BREAST NEOPLASMS; CARCINOMA, INFILTRATING DUCT; GENE AMPLIFICATION; HUMAN; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, ESTRADIOL;

EID: 0027993963     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-8049(94)90128-7     Document Type: Article

References (16)

1. p53 mutations in human cancers
2. Prognostic significance of TP53 alterations in breast carcinoma
3. Somatic p53 mutations in human breast carcinomas in an Icelandic population: a prognostic factor
4. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
5. The MDM2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
6. MDM2 expression is induced by wild type p53 activity
7. Amplification of a gene encoding a p53-associated protein in human sarcomas
8. MDM2 gene amplification in metastatic osteosarcoma
9. Identification and cloning of a novel amplified DNA sequence in human malignant fibrous histiocytoma derived from a region of chromosome 12 frequently rearranged in soft tissue tumors
10. Absence of amplification of MDM2 gene, a regulator of p53 function, in myelodysplastic syndromes
11. The p53-binding protein MDM2 gene is differentially expressed in human breast carcinoma.
12. Mutations in human breast cancer: an overview
13. Prognostic significance of insulin-like growth factor 1 receptors in human breast cancer
14. Standardization of steroid receptor assays in human breast cancer. IV: Long-term within and between laboratory variation of estrogen and progesterone receptor assays
15. Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas