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Volumn 35, Issue 33, 1994, Pages 6123-6126

Diastereoselective catalytic asymmetric nitroaldol reaction utilizing rare earth-Li-(R)-BINOL complex. A highly efficient synthesis of norstatine

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 2 HYDROXY 4 PHENYLBUTYRIC ACID; ANTIVIRUS AGENT; KNI 227; KYNOSTATIN 272; UNCLASSIFIED DRUG;

EID: 0027993912     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(94)88093-X     Document Type: Article
Times cited : (116)

References (22)
  • 14
    • 0001297451 scopus 로고
    • 2 mediated cyanohydrin-forming reaction of N,N-dibenzyl-α-aminoaldehyde 5 with TMSCN (79% yield, 90% de); see, [[Comment]]
    • (1988) Tetrahedron Lett. , vol.27 , pp. 3295-3298
    • Reetz1    Drewes2    Harms3    Reif4
  • 17
    • 84913075056 scopus 로고    scopus 로고
    • 2O/MeCN = 55/45 as an eluent) and the erythro configuration of 4a was determined by conversion into known AHPA 2; see reference 7.
  • 18
    • 84913073940 scopus 로고    scopus 로고
    • The enantiomeric excess was determined by HPLC analysis using DAICEL CHIRALCEL OJ (for 4a,4b,4c) or CHIRALPAK AD (for 4d, 4e, 4f, 4g).
  • 19
    • 84913072634 scopus 로고    scopus 로고
    • 3N; 86% yield (erythro : threo = 74 : 26), KF; 73% yield (e : t = 56 : 44), KO-t-Bu; 86% yield (e : t = 61 : 39), KOH; 72% yield (e : t = 66 : 34).
  • 20
    • 84913040731 scopus 로고    scopus 로고
    • Sakai, K.; Takahashi, K.; Terashima, S.; Tsunemoto, D.; Kamijo, T.; Harada, H. Jpn. Kokai Tokkyo Koho JP02 59545 [90 59545] (CA 113: 98035q)
  • 21
    • 85004872164 scopus 로고
    • An Efficient Synthesis of Optically Active α-(t-Butoxycarbonylamino)-aldehydes from α-Amino Acids
    • (1983) Synthesis , pp. 676-678
    • Fehrentz1    Castro2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.