Rational design of potent carboxylic acid based bisubstrate inhibitors of ras farnesyl protein transferase

Bioorganic and Medicinal Chemistry Letters

Volumn 4, Issue 17, 1994, Pages 2107-2112

  Bhide, Rajeev S ^a   Patel, Dinesh V ^a   Patel, Manorama M ^a   Robinson, Simon P ^a   Hunihan, Lisa W ^a   Gordon, Eric M ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYSTEINYLVALYLLEUCYLSERINE; ENZYME INHIBITOR; OLIGOPEPTIDE; PROTEIN FARNESYLTRANSFERASE; TETRAPEPTIDE; TRANSFERASE; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG; VALYLLEUCYLSERINE DERIVATIVE;

ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

EID: 0027989834     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)80111-6     Document Type: Article

References (12)