A component of DNA double-Strand break repair is dependent on the spatial orientation of the lesions within the higher-order structures of chromatin

International Journal of Radiation Biology

Volumn 66, Issue 5, 1994, Pages 531-536

  Johnston, P J ^a   Bryant, P E ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; CHO CELL; CHROMATIN STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; DNA STRAND BREAKAGE; IONIZING RADIATION; PRIORITY JOURNAL;

ANIMAL; CHO CELLS; CHROMATIN; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; HAMSTERS; SUPPORT, NON-U.S. GOV'T;

EID: 0027988569     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553009414551571     Document Type: Article

References (26)

1. X-ray-induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution
2. Supercoils in human DNA
3. Characterisation of nuclear structures containing superhelical DNA
4. Repair of DNA single-strand and double-strand breaks in the Chinese hamster xrs-5 mutant cell line as determined by DNA unwinding
5. Reparable and non-reparable DNA strand breaks induced by X-irradiation in CHO K1 cells and the radiosensitive mutants xrs1 and xrs5
6. Supercoiled DNA repair in thymocyte fractions differing in radiosensitivity
7. Spatial and temporal distribution of DNA replication sites localised by immunofluorescence and confocal microscopy in mouse fibroblasts
8. The organisation of chromatin loops: Characterisation of a scaffold attachment site
9. Initial events in the cellular effects of ionising radiations: clustered damage in DNA
10. Organisation of mammalian chromosomal DNA: supercoiled and folded circular DNA subunits from interphase cell nuclei
11. Visualisation of replication factories attached to a nucleoskeleton
12. Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose dependent: implications for the mechanism of radiosensitivity
13. X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA damaging agents
14. X-ray sensitive mutants of Chinese hamster ovary cells deficient in double-strand break rejoining
15. Relation of chromosome structure and gene expression
16. Scaffold attachment of DNA loops in metaphase chromosomes
17. Organisation of the higher order chromatin loop: Specific DNA attachment sites on nuclear scaffold
18. Variation through the cell cycle of DNA neutral filter elution dose response in X-irradiated synchronous CHO cells
19. Metaphase chromosome and nucleoid differences between CHO-K1 and its radiosensitive derivative xrs-5
20. Association between radiation sensitivity, DNA repair, and chromosome organisation in the Chinese hamster ovary cell line xrs-5
21. DNA supercoiled domains and radio-sensitivity of subpopulations of human peripheral blood lymphocytes
22. Changes in DNA supercoiling during repair of gamma-radiation-induced damage
23. Radiation sensitivities are not related to the sizes of supercoiled domains in L5178Y-R and L5178Y-S cells
24. Nuclear scaffold organisation in the X-ray sensitive Chinese hamster mutant cell line, xrs-5
25. Changes in the nuclear structure in the radiation-sensitive CHO mutant, xrs-5