The Glycine Site on the NMDA Receptor: Structure-Activity Relationships and Therapeutic Potential

Journal of Medicinal Chemistry

Volumn 37, Issue 24, 1994, Pages 4053-4067

  Leeson, Paul D ^a   Iversen, Leslie L ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 INDOLECARBOXYLIC ACID; 3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 3 AMINO 1 HYDROXY 4 METHYL 2 PYRROLIDINONE; 4 (3 PHOSPHONOALLYL) 2 PIPERAZINECARBOXYLIC ACID; 4 PHOSPHONOMETHYLPIPECOLIC ACID; 5,7 DICHLORO 1,2,3,4 TETRAHYDRO 4 (3 PHENYLUREIDO) 2 QUINOLINECARBOXYLIC ACID; 5,7 DICHLOROKYNURENIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; 6,7 DINITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINO ACID RECEPTOR STIMULATING AGENT; CYCLOBUTANE; CYCLOPROPANE; CYCLOSERINE; DIZOCILPINE; DRUG CARRIER; GLYCINE; KYNURENIC ACID DERIVATIVE; KYNURENINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROLEPTIC AGENT; QUINOLONE DERIVATIVE; QUINOXALINE DERIVATIVE;

ANTICONVULSANT ACTIVITY; BRAIN PROTECTION; COGNITION; DRUG RECEPTOR BINDING; HUMAN; HYPERALGESIA; NEUROTOXICITY; NONHUMAN; PAIN; REVIEW; STRUCTURE ACTIVITY RELATION; TRANQUILIZING ACTIVITY;

ANIMAL; ANTI-ANXIETY AGENTS; ANTIPSYCHOTIC AGENTS; BINDING SITES; COGNITION; GLYCINE; HUMAN; KYNURENIC ACID; NEUROPROTECTIVE AGENTS; PYRROLIDINONES; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0027988561     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00050a001     Document Type: Article

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