Structure-Activity Studies of the Binding of Modified Peptide Nucleic Acids (PNAs) to DNA

Journal of the American Chemical Society

Volumn 116, Issue 18, 1994, Pages 7964-7970

  Hyrup, Birgitte ^a   Egholm, Michael ^a   Buchardt, Ole ^a   Nielsen, Peter E ^b   Wittung, Pernilla ^c   Norden, Bengt ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEIC ACID DERIVATIVE; OLIGOMER; OLIGONUCLEOTIDE; PEPTIDE DERIVATIVE; PEPTIDE NUCLEIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DNA BINDING; HYBRID; STRUCTURE ACTIVITY RELATION;

EID: 0027986543     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja00097a002     Document Type: Article

References (16)

1. Uhlmann, E.; Peyman, A. Chem. Rev. 1990, 90, 544-584.
2. Crook, S. T. Curr. Opin. Biotechnol. 1992, 3, 656-661.
3. English, U.; Gauss, D. H. Angew. Chem., Int. Ed. Engl. 1991, 30, 613-722.
4. Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Science 1991, 254, 1497-1500.
5. Egholm, M.; Buchardt, O.; Nielsen, P. E.; Berg, R. H. J. Am. Chem. Soc. 1992, 114, 1895-1897.
6. Egholm, M.; Nielsen, P. E.; Buchardt, O.; Berg, R. H. J. Am. Chem. Soc. 1992, 114, 9677-9678.
7. Egholm, M.; Christensen, L.; Behrens, C.; Berg, R. H.; Nielsen, P. E.; Buchardt, O. J. Chem. Soc., Chem. Commun. 1993, 800-801.
8. Demidov, V. V.; Potaman, V. N.; Frank-Kamenetskii, M. D.; Egholm, M.; Buchanrd, O.; Sönnichsen, S. H.; Nielsen, P. E. In preparation.
9. Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. In Antisense Research and Applications; Crooke, S. T., Lebleu, B., Eds.; CRC Press: Boca Raton, FL, 1992; pp 363-372.
10. Hyrup, B.; Egholm, M.; Rolland, M.; Berg, R. H.; Nielsen, P. E.; Buchardt, O. J. Chem. Soc., Chem. Commun. 1993, 518-519.
11. Kim, S. K.; Nielsen, P. E.; Egholm, M.; Buchardt, O.; Berg, R. H.; Norden, B. J. Am. Chem. Soc. 1993, 114, 6477-6481.
12. Egholm, M.; Buchardt, O.; Christensen, L.; Behrens, C.; Freier, S. M.; Driver, D. A.; Berg, R. H.; Kim, S. K.; Nordin, B.; Nielsen, P. E. Nature 1993, 365, 566-568.
13. Wittung, P.; Nielsen, P. E.; Buchardt, O.; Egholm, M.; Norden, B. Nature 1994, 368, 561-563.
14. Almarsson, O.; Bruice, T. C. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 9542-9546.
15. Almarsson, O.; Bruice, T. C.; Kerr, J.; Zuckermann, R. N. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 7518-7522.
16. Dueholm, K.; Egholm, M.; Behrens, C.; Christensen, L.; Hansen, H. F.; Vulpius, T.; Petersen, K. H.; Berg, R. H.; Nielsen, P. E.; Buchardt, O. Submitted for publication in J. Org. Chem.