Genetic mapping of the batten disease locus (CLN3) to the interval d16s288-d16s383 by analysis of haplotypes and allelic association

Genomics

Volumn 22, Issue 2, 1994, Pages 465-468

  Mitchison, Hannah M ^a   Taschner, Peter E M ^b   O’Rawe, Angela M ^a   De Vos, Nanneke ^b   Phillips, Hilary A ^c   Thompson, Andrew D ^c   Kozman, Helen M ^c   Haines, Jonathan L ^d,e   Schlumpf, Karen ^d   D’Arigo, Kenneth ^d   Boustany, Rose Mary N ^f   Callen, David F ^c   Breuning, Martijn H ^b   Gardiner, R Mark ^a   Mole, Sara E ^a   Lerner, Terry J ^e  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b LEIDEN UNIVERSITY   (Netherlands)

^c WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 16P; GENE LOCATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MARKER GENE; NEURONAL CEROID LIPOFUSCINOSIS; PEDIGREE ANALYSIS; PRIORITY JOURNAL;

ALLELES; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 16; CROSSING OVER (GENETICS); DNA, SATELLITE; GENETIC MARKERS; HAPLOTYPES; HUMAN; LINKAGE DISEQUILIBRIUM; MALE; MOLECULAR SEQUENCE DATA; NEURONAL CEROID-LIPOFUSCINOSIS; RECOMBINATION, GENETIC; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027982645     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1006/geno.1994.1412     Document Type: Article

References (6)

1. Callen, D. F., Doggett, N. A., Stallings, R. L., Chen, L. Z., Whitmore, S. A., Lane, S. A., Nancarrow, J. K, Apostolou, S., Thompson, A. D., Lapsys, N. M., Eyre, H. J., Baker, E. G., Shun, Y., Holman, K., Phillips, H., Richards, R. I., and Sutherland, G. R. (1992). High-resolution cytogenetic-based physical map of human chromosome 16. Genomics 13: 1178-1185.
2. Lemer, T. J., Boustany, R.-M., MacCormack, K., Gleitsman, J., Schlumpf, K., Breakefield, X. O., Gusella, J. F., and Haines, J. L. (1993). Linkage disequilibrium between the juvenile NCL gene (CLN3) and marker loci on chromosome 16pl2.1. Am, J. Hum. Genet. 54: 88-94.
3. Mitchison, H. M., Thompson, A. D., Mulley, J. C., Kozman, H. M., Richards, R. I., Callen, D. F., Stallings, R. L., Doggett, N. A., Attwood, J., McKay, T. R., Sutherland, G. R., and Gardiner, R. M. (1993). Fine genetic mapping of the Batten disease locus (CLN3) by haplotype analysis and demonstration of allelic association with chromosome 16p microsatellite loci. Genomics 16: 455-460.
4. Mitchison, H. M., Williams, R. E., McKay, T. R., Callen, D. F., Thompson, A. D., Mulley, J. C., Stallings, R. L., Hildebrand, C. E., Moyzis, R. K., Jarvela, I., Pelfconen, L., Haines, J., Sutherland, G. R., and Gardiner, R. M. (1993). Refined genetic mapping of juvenile-onset Neuronal Ceroid-lipofuscinosis on chromosome 16. J. Inker. Metab. Dis. 16: 339-341.
5. Rogaev, E. I., and Keryanov, S. A. (1992). Unusual variability of the complex dinucleotide repeat block at the SPN locus. Hu m. Mol. Genet. 1: 657.
6. Shen, Y., Holman, K, Doggett, N. A., Callen, D. F., Sutherland, G. R., and Richards, R. I. (1993). Four dinucleotide repeat polymorphisms on human chromosome 16. Hum. Mol. Genet. 2: 1745.