1-Phosphatidylinositol 3-kinase activity is required for insulin- stimulated glucose transport but not for RAS activation in CHO cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 91, Issue 16, 1994, Pages 7415-7419

  Hara, K ^a   Yonezawa, K ^a   Sakaue, H ^a   Ando, A ^a   Kotani, K ^a   Kitamura, T ^a   Kitamura, Y ^a   Ueda, H ^a   Stephens, L ^a   Jackson, T R ^a   Hawkins, P T ^a   Dhand, R ^a   Clark, A E ^a   Holman, G D ^a   Waterfield, M D ^a   Kasuga, M ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

glucose transporters; insulin receptor substrate 1; translocation

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; INSULIN RECEPTOR; PHORBOL 12 ACETATE 13 MYRISTATE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; RAS PROTEIN; TRIPHOSPHOINOSITIDE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBUNIT; GENE ACTIVATION; GLUCOSE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMAL; BIOLOGICAL TRANSPORT; CHO CELLS; COMPARATIVE STUDY; DNA MUTATIONAL ANALYSIS; GLUCOSE; HAMSTERS; INSULIN; MONOSACCHARIDE TRANSPORT PROTEINS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEIN P21(RAS); SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0027981333     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.91.16.7415     Document Type: Article

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