Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein

Journal of Virology

Volumn 68, Issue 3, 1994, Pages 1689-1696

  Dorfman, Tatyana ^b   Mammano, Fabrizio ^b   Haseltine, William A ^b   Göttlinger, Heinrich G ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; MATRIX PROTEIN; SINGLE STRANDED DNA; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; VIRUS RNA;

ANTIGEN RECOGNITION; ARTICLE; CELL CULTURE; DNA TRANSFECTION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROVIRUS; RNA ANALYSIS; VIRION; VIRUS INFECTIVITY; VIRUS PARTICLE;

EID: 0027979135     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.68.3.1689-1696.1994     Document Type: Article

References (46)

1. Arthur, L. O., J. W. Bess, R. C. Sowder II, R. E. Benveniste, D. L. Mann, J.-C. Chermann, and L. E. Henderson. 1992. Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines. Science 258:1935-1938.
2. Brody, B. A., S. S. Rhee, M. A. Sommerfelt, and E. Hunter. 1992. A viral protease-mediated cleavage of the transmembrane glycoprotein of Mason-Phizer monkey virus can be suppressed by mutations within the matrix protein. Proc. Natl. Acad. Sci. USA 89:3443-3447.
3. Bryant, M., and L. Ratner. 1990. Myristoylation-dependent replication and assembly of human immunodeficiency virus 1. Proc. Natl. Acad. Sci. USA 87:523-527.
4. Cullen, B. R. 1987. Use of eukaryotic expression technology in the functional analysis of cloned genes. Methods Enzymol. 152:684-704.
5. Dorfman, T., J. Luban, S. P. Goff, W. A. Haseltine, and H. G. Göttlinger. 1993. Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein. J. Virol. 67:6159-6169.
6. Duhay, J. W., S. J. Roberts, B. H. Hahn, and E. Hunter. 1992. Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity. J. Virol. 66:6616-6625.
7. Fäcke, M., A. Janetzko, R. L. Shoeman, and H. G. Kräusslich. 1993. A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum. J. Virol. 67:4972-4980.
8. Gabuzda, D. H., A. Lever, E. Terwilliger, and J. Sodroski. 1992. Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins. J. Virol. 66:3306-3315.
9. Gallaher, W. R., J. M. Ball, R. F. Garry, M. C. Griffin, and R. C. Montelaro. 1989. A general model for the transmembrane proteins of HIV and other retroviruses. AIDS Res. Hum. Retroviruses 5:431-440.
10. Gebhardt, A., J. V. Bosch, A. Ziemiecki, and R. R. Friis. 1984. Rous sarcoma virus p19 and gp35 can be chemically crosslinked to high molecular weight complexes. J. Mol. Biol. 174:297-317.
11. Gelderblom, H. R., E. H. Hausmann, M. Özel, G. Pauli, and M. A. Koch. 1987. Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology 156:171-176.
12. Gelderblom, H. R., H. Reupke, and G. Pauli. 1985. Loss of envelope antigens of HTLV-III/LAV, a factor in AIDS pathogenesis? Lancet ii:1016-1017.
13. Göttlinger, H. G. Unpublished observation.
14. Göttlinger, H. G., T. Dorfman, E. A. Cohen, and W. A. Haseltine. 1993. Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses. Proc. Natl. Acad. Sci. USA 90:7381-7385.
15. Göttlinger, H. G., J. G. Sodroski, and W. A. Haseltine. 1989. Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 86:5781-5785.
16. Hunter, E., and R. Swanstrom. 1990. Retrovirus envelope glycoproteins. Curr. Top. Microbiol. Immunol. 157:187-253.
17. Katoh, I., H. Kyushiki, Y. Sakamoto, Y. Ikawa, and Y. Yoshinaka. 1991. Bovine leukemia virus matrix-associated protein MA (p15): further processing and formation of a specific complex with the dimer of the 5′-terminal genomic RNA fragment. J. Virol. 65: 6845-6855.
18. Kimpton, J., and M. Emerman. 1992. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene. J. Virol. 66:2232-2239.
19. Landau, N. R., and D. R. Littman. 1992. Packaging system for rapid production of murine leukemia virus vectors with variable tropism. J. Virol. 66:5110-5113.
20. Landau, N. R., K. A. Page, and D. R. Littman. 1991. Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range. J. Virol. 65:162-169.
21. Lusso, P., F. M. Veronese, B. Ensoli, G. Franchini, C. Jemma, S. E. DeRocco, V. S. Kalyanaraman, and R. C. Gallo. 1990. Expanded HIV-1 cellular tropism by phenotypic mixing with murine endogeneous retroviruses. Science 247:848-852.
22. Owens, R. J., J. W. Dubay, E. Hunter, and R. W. Compans. 1991. Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells. Proc. Natl. Acad. Sci. USA 88:3987-3991.
23. Pepinsky, R. B., and V. M. Vogt. 1979. Identification of retrovirus matrix proteins by lipid-protein cross-linking. J. Mol. Biol. 131: 819-837.
24. Pepinsky, R. B., and V. M. Vogt. 1984. Fine-structure analyses of lipid-protein and protein-protein interactions of gag protein p19 of the avian sarcoma and leukemia viruses by cyanogen bromide mapping. J. Virol. 52:145-153.
25. Perez, L. G., G. L. Davis, and E. Hunter. 1987. Mutants of the Rous sarcoma virus envelope glycoprotein that lack the transmembrane anchor and cytoplasmic domains: analysis of intracellular transport and assembly into virions. J. Virol. 61:2981-2988.
26. Queen, C., and D. Baltimore. 1983. Immunoglobulin gene transcription is activated by downstream sequence elements. Cell 33:741-748.
27. gag is essential for virus particle formation by Moloney murine leukemia virus. Proc. Natl. Acad. Sci. USA 83:7246-7250.
28. Rhee, S. S., and E. Hunter. 1987. Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids. J. Virol. 61:1045-1053.
29. Rhee, S. S., and E. Hunter. 1990. A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus. Cell 63:77-86.
30. Rhee, S. S., and E. Hunter. 1990. Structural role of the matrix protein of type D retroviruses in Gag polyprotein stability and capsid assembly. J. Virol. 64:4383-4389.
31. Rhee, S. S., and E. Hunter. 1991. Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport and membrane association of a capsid. EMBO J. 10:535-546.
32. Rice, N. R., L. E. Henderson, R. C. Sowder, T. D. Copeland, S. Oroszlan, and J. F. Edwards. 1990. Synthesis and processing of the transmembrane envelope protein of equine infectious anemia virus. J. Virol. 64:3770-3778.
33. Schultz, A. M., and S. Oroszlan. 1983. In vivo modification of retroviral gag gene-encoded polyproteins by myristic acid. J. Virol. 46:355-361.
34. Spector, D. H., E. Wade, D. A. Wright, V. Koval, C. Clark, D. Jaquish, and S. A. Spector. 1990. Human immunodeficiency virus pseudotypes with expanded cellular and species tropism. J. Virol. 64:2298-2308.
35. Staskus, K. A., E. F. Retzel, E. D. Lewis, J. L. Silsby, S. St. Cyr, J. M. Rank, S. W. Wietgrefe, A. T. Haase, R. Cook, D. Fast, P. T. Geiser, J. T. Harty, S. H. Kong, C. J. Lahti, T. P. Neufeld, T. E. Porter, E. Shoop, and K. R. Zachow. 1991. Isolation of replication-competent molecular clones of visna virus. Virology 181:228-240.
36. Stephens, R. M., J. W. Casey, and N. R. Rice. 1986. Equine infectious anemia virus gag and pol genes: relatedness to visna and AIDS virus. Science 231:589-594.
37. Terwilliger, E. F., E. A. Cohen, Y. Lu, J. G. Sodroski, and W. A. Haseltine. 1989. Functional role of human immunodeficiency virus type 1 vpu. Proc. Natl. Acad. Sci. USA 86:5163-5167.
38. Weaver, T., and A. T. Panganiban. 1990. N myristoylation of the spleen necrosis virus matrix protein is required for correct association of the Gag polyprotein with intracellular membranes and for particle formation. J. Virol. 64:3995-4001.
39. Wilk, T., T. Pfeiffer, and V. Bosch. 1992. Retained in vitro infectivity and cytopathogenicity of HIV-1 despite truncation of the C-terminal tail of the env gene product. Virology 189:167-177.
40. Wills, J. W., and R. C. Craven. 1991. Form, function, and use of retroviral Gag proteins. AIDS 5:639-654.
41. src. J. Virol. 65:3804-3812.
42. Wilson, C., M. S. Reitz, H. Okayama, and M. V. Eiden, M. V. 1989. Formation of infectious hybrid virions with gibbon ape leukemia virus and human T-cell leukemia virus retroviral envelope glycoproteins and the gag and pol proteins of Moloney murine leukemia virus. J. Virol. 63:2374-2378.
43. Yao, X. J., H. Göttlinger, W. A. Haseltine, and E. A. Cohen. 1992. Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export. J. Virol. 66:5119-5126.
44. Yu, X., Q.-C. Yu, T.-H. Lee, and M. Essex. 1992. The C terminus of human immunodeficiency virus type 1 matrix protein is involved in early steps of the virus life cycle. J. Virol. 66:5667-5670.
45. Yu, X., X. Yuan, Z. Matsuda, T.-H. Lee, and M. Essex. 1992. The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions. J. Virol. 66:4966-4971.
46. Yu, X., X. Yuan, M. F. McLane, T.-H. Lee, and M. Essex. 1993. Mutations in the cytoplasmic domain of human immunodeficiency virus type 1 transmembrane protein impair the incorporation of Env proteins into mature virions. J. Virol. 67:213-221.