Localization of Drug‐Metabolizing Enzyme Activities to Blood‐Brain Interfaces and Circumventricular Organs

Journal of Neurochemistry

Volumn 62, Issue 3, 1994, Pages 1089-1096

  Ghersi Egea J F ^a   Leninger Muller B ^a   Suleman, G ^a   Siest, G ^a   Minn, A ^a  

^a Centre du Medicament URA CNRS 597   (France)

Author keywords

Blood brain barrier; Choroid plexuses; Circumventricular organs; Cytochrome P 450; Drug metabolizing enzymes; Epoxide hydrolase; UDP glucuronosyltransferase

Indexed keywords

DRUG METABOLIZING ENZYME; EPOXIDE HYDROLASE; GLUCURONOSYLTRANSFERASE; MEMBRANE ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; TRITON X 100;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PROTECTION; BRAIN TISSUE; CHOROID PLEXUS; DRUG METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; LIVER METABOLISM; MALE; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; BLOOD-BRAIN BARRIER; BRAIN; CEREBRAL VENTRICLES; CHOROID PLEXUS; CYTOCHROME P-450 ENZYME SYSTEM; EPOXIDE HYDROLASES; GLUCURONOSYLTRANSFERASE; ISOENZYMES; MALE; PHARMACEUTICAL PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

ANIMALIA; ARACHNOIDEA;

EID: 0027976519     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1994.62031089.x     Document Type: Article

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