The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen

Journal of Experimental Medicine

Volumn 179, Issue 1, 1994, Pages 317-321

  Mullbacher A ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMAL; ANTIGENS, VIRAL; FEMALE; IMMUNOLOGIC MEMORY; INFLUENZA A VIRUS; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED;

EID: 0027972541     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.179.1.317     Document Type: Article

References (25)

1. Kocks, C., and K. Rajewsky. 1989. Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways.Annu. Rev. Immunol.7:537.
2. Medawar, P. 1944. The behaviour and fate of skin autografts and skin homografts in rabbits.J. Anat.78:176.
3. Gardner, I.D., and R.V. Blanden. 1976. The cell-mediated immune response to ectromelia virus infection. II. Secondary response in vitro and kinetics of memory T cell production in vivo.Cell, Immunol.22:283.
4. Müllbacher, A., and R.V. Blanden. 1978. Murine cytotoxic T-cell response to alphavirus is associated mainly with H-2Dk.Immunogenetics.7:551.
5. Ashman, R. 1982. Persistence of cell-mediated immunity to influenza A virus in mice.Immunology.47:165.
6. Effros, R.B., J. Bennink, and P.C. Doherty. 1978. Characteristics of secondary cytotoxic T-cell responses in mice infected with influenza A viruses.Cell. Immunol.36:345.
7. Hill, A.B., R.V. Blanden, C.R. Parrish, and A. Mullbacher. 1992. Restimulated memory Tc cells have a higher apparent avidity of interaction with targets than primary virus-immune Tc cells as indicated by anti-CD8 blocking.Immunol. Cell Biol.70:259.
8. Blanden, R.V., U. Kees, and M.B.C. Dunlop. 1977. In vitro primary induction of cytotoxic T cells against virus-infected syngeneic cells.J. Immunol. Methods.16:73.
9. Kos, F.J., and A. Müllbacher. 1992. Induction of primary antiviral cytotoxic T cells by in vitro stimulation with short synthetic peptide and interleukin-7.Eur. J. Immunol.22:3183.
10. Macatonia, S.E., P.M. Taylor, S.C. Knight, and B. A. Askonas. 1989. Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro .J. Exp. Med.169:1255.
11. Nonacs, R., C. Humborg, J.P. lam, and R.M. Steinman. 1992. Mechanisms of mouse spleen dendritic cell function in the generation of influenza-specific, cytolytic T lymphocytes.J. Exp Med.176:519.
12. Akbar, A., M. Salmon, and G. Janossy. 1991. The synergy between naive and memory T cells during activation.Immunol. Today.12:184.
13. +cytotoxic T cell activation and memory in virus infection.J. Immunol.149:1326.
14. Cerottini, J.-C., and H.R. MacDonald. 1989. The cellular basis of T-cell memory.Annu. Rev. Immunol.7:77.
15. Beverley, P.C.L. 1990. Is T-cell memory maintained by crossreactive stimulation?Immunol. Today.11:203.
16. Gray, D., and P. Matzinger. 1991. T cell memory is short-lived in the absence of antigen.J. Exp. Med.174:969.
17. Yap, K.L., and G.L. Ada. 1977. Cytotoxic T cells specific for influenza virus infected target cells.Immunology.32:151.
18. Müllbacher, A., A. Hill, R. Blanden, W. Cowden, N. King, and R. Tha Hla. 1991. Alloreactive cytotoxic T cells recognise MHC class I antigen without peptide specificity.J. Immunol.147:1765.
19. Eichelberger, M., M. Wang, W. Allan, R. Webster, and P. Doherty. 1991. Influenza virus RNA in the lung and lymphoid tissue of immunologically intact and CD4-depleted mice.J. Gen. Virol.72:1695.
20. Jamieson, B.D., and R. Ahmed. 1989. T cell memory. Longterm persistence of virus-specific cytotoxic T cells. J.Exp. Med.169:1993.
21. Miillbacher, A., G. Ada, and R. Tha Hla. 1988. Gamma-irradiated influenza A virus can prime for a cross-reactive and cross-protective immune response against influenza A virus.Immunol. Cell Biol.66:153.
22. +memory cytotoxic T cells by B cell-derived factors.Immunobiology.185:410.
23. Liu, Y., and A. Miillbacher. 1989. Activated B cells can deliver help for the in vitro generation of antiviral cytotoxic T cells.Proc. Natl. Acad. Sci. USA.86:4629.
24. Gray, D., M. Kosco, and B. Stockinger. 1991. Novel pathways of antigen presentation for the maintenance of memory.Int. Immunol.3:141.
25. Humphrey, J., D. Grennan, and V. Sundaram. 1984. The origin of follicular dendritic cells in the mouse and the mechanism of trapping of immune complexes on them.Eur. J. Immunol.14:859.