Synthesis of the A/E/F tricyclic section of the norditerpenoid alkaloid methyllycaconitine, a potent inhibitor of neurotransmission

Journal of the Chemical Society, Chemical Communications

Volumn , Issue 21, 1994, Pages 2487-2488

  Baillie, Lynn C ^a   Bearder, John R ^b   Whiting, Donald A ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Shell Research Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; NEUROTRANSMITTER UPTAKE INHIBITOR; TERPENOID DERIVATIVE; TRICYCLIC AROMATIC COMPOUND;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NEUROTRANSMISSION;

EID: 0027970564     PISSN: 00224936     EISSN: None     Source Type: Journal    
DOI: 10.1039/C39940002487     Document Type: Article

References (15)

1. M. S. Yunusov, Nat. Prod. Rep., 1991, 8, 499.
2. S. W. Pelletier, N. V. Mody, K. Varughese, J. A. Maddry and H. K. Desai, J. Am. Chem. Soc., 1981, 103, 6536.
3. R. H. F. Manske, Can. J. Res., 1938, 16B, 57.
4. S. W. Pelletier, S. A. Ross and P. Kulanthaivel, Tetrahedron, 1989, 45, 1887.
5. A. Drasdo, M. Caulfield, D. Bertrand, S. Bertrand and S. Wonnacott, Mol. Cell. NeuroSci., 1992, 3, 237.
6. S. Wonnacott, E. X. Alberquerque and D. Bertrand, Method Neurosci., 1993, 12, 263.
7. I. S. Blagborough, D. J. Hardick, S. Wonnacott and B. V. L. Potter, Tetrahedron Lett., 1994, 35, 3367.
8. I. S. Blagborough, D. J. Hardick, S. Wonnacott and B. V. L. Potter, Tetrahedron Lett., 1994, 35, 3371.
9. W. M. Roush, H. R. Gillis and A. I. Ko, J. Am. Chem. Soc., 1982, 104, 2269.
10. T. Hudlicky, F. J. Koszyk, T. M. Kutchan and J. P. Sheth, J. Org. Chem., 1980, 45, 5020.
11. S. M. Weinreb, N. A. Khatri and J. Shringarpure, J. Am. Chem. Soc., 1979, 101, 5073.
12. P. A. Grieco, K. Yoshido and P. Garner, J. Org. Chem., 1983, 48, 3137.
13. P. A. Grieco, Aldrichim. Acta, 1991, 24, 59.
14. C. W. Gribble, F. L. Switzer and R. M. Soll, J. Org. Chem., 1988, 53, 3164.
15. A. Batsanov, personal communication.