Allelic D variants of transferrin in evaluation of alcohol abuse: Differential diagnosis by isoelectric focusing-immunoblotting-laser densitometry

Clinical Chemistry

Volumn 40, Issue 11 I, 1994, Pages 2078-2083

  Bean, Pamela ^a   Peter, James B ^a  

^a Specialty Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFERRIN;

ALCOHOL ABUSE; ALCOHOL BLOOD LEVEL; ALCOHOLISM; ARTICLE; DIFFERENTIAL DIAGNOSIS; HUMAN; IMMUNOBLOTTING; ISOELECTRIC FOCUSING;

EID: 0027970447     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/40.11.2078     Document Type: Article

References (19)

1. de Jong G, van Eijk HG. Functional properties of the carbohydrate moiety of human transferrin. Int J Biochem 1989;21:258-63.
2. Giblett ER. The plasma transferrins [Review]. Prog Med Genet 1962;2:34-6.
3. van Noort WL, van Eijk HG. Separation of human serum and cerebrospinal fluid transferrins in subfractions by isoelectric focusing with Phast system and quantitations with Vetroscan XL densitometer. Sci Tools 1992;36:1-6.
4. Bean P, Peter JB. A new approach to quantitate carbohydrate-deficient transferrin isoforms in alcohol abusers: partial iron saturation in isoelectric focusing/immunoblotting and laser densitometry. Alcohol Clin Exp Res 1993;17:1163-70.
5. Stibler H. Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed. Clin Chem 1991;37:2029-37.
6. Xin Y, Lasker JM, Rosman AS, Lieber CS. Isoelectric focusing/ Western blotting: a novel and practical method for quantitation of carbohydrate-deficient transferrin in alcoholics. Alcohol Clin Exp Res 1991;15:814-21.
7. Jeppsson JO, Kristensson H, Fimiani C. Carbohydrate-deficient transferrin quantified by HPLC to determine heavy consumption of alcohol. Clin Chem 1993;39:2115-20.
8. Lof K, Koivula T, Seppa K, Fukunaga T, Sillanaukee P. Semi-automatic method for determination of different isoforms of carbohydrate-deficient transferrin. Clin Chim Acta 1993;217:175-86.
9. Anton R, Bean P. Comparison of two methods of carbohydrate-deficient transferrin measurement in inpatient alcoholics and healthy controls. Clin Chem 1994;40:364-8.
10. Xin Y, Rosman AS, Lasker JM, Lieber CS. Measurement of carbohydrate-deficient transferrin by isoelectric focusing/Western blotting and by micro anion-exchange chromatography/radioimmunoassay: comparison of diagnostic accuracy. Alcohol Alcohol 1992;27:425-33.
11. Pascali VL, Dobosz M, Destro-Bisol G, D'Aloja E. Characterization of genetic variants of human serum transferrin by isoelectric focusing: comparison between conventional and immobilized pH gradients, and application to a protocol for paternity testing. Electrophoresis 1988;9:411-7.
12. Kamboh MI, Ferrell RE. Human transferrin polymorphism [Review]. Hum Hered 1987;37:65-81.
13. Dykes DD, DeFurio CM, Polesky HF. Isoelectric focusing for transferrin (TF) subtypes in parentage testing. Am J Clin Pathol 1983;79:725-7.
14. Reinhart MP, Malamud D. Protein transfer from isoelectric focussing gels: the native blot. Anal Biochem 1982;123:229-35.
15. Blake ET. Progressive desialidation of human transferrin. J Foren Sci 1987;32:1342-7.
16. Stibler H, Jacken J. Carbohydrate-deficient serum transferrin in a new hereditary syndrome. Arch Dis Child 1990;65:107-11.
17. Wada Y, Nishikawa A, Okamoto N, Inui K, Tsukamoto H, Okada S, Taniguchi N. Structure of serum transferrin in carbohydrate-deficient glycoprotein syndrome. Biochem Biophys Res Commun 1992;189:832-6.
18. Giblett ER, Hickman CG, Smithies O. Serum transferrins. Nature 1959;183:1589-90.
19. Yuasa I, Saneshige Y, Suenaga K, Ito K, Gotoh Y. Transferrin variants in Japan and New Zealand: report of an unusually sialyzed TF variant. Hum Hered 1987;37:20-5.